Results 11 to 20 of about 180,856 (396)
Nature Communications, 2018 How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify ...
Ralf Gilsbach +2 more
exaly +3 more sources
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling
Nature Communications, 2017 Chronic cardiac stress induces pathologic hypertrophy and fibrosis of the myocardium. The microRNA-29 (miR-29) family has been found to prevent excess collagen expression in various organs, particularly through its function in fibroblasts.
Yassine Sassi +2 more
exaly +2 more sources
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2003 It is generally believed that increase in adult contractile cardiac mass can be accomplished only by hypertrophy of existing myocytes. Documentation of myocardial regeneration in acute stress has challenged this dogma and led to the proposition that ...
Anversa P. +9 more
core +2 more sources
A Broad-Spectrum Chemokine Inhibitor Drives M2 Macrophage Polarization Through Modulation of the Myometrial Secretome [PDF]
CellsThe uterine smooth muscle (myometrium) is an immunomodulatory tissue capable of secreting multiple chemokines during pregnancy. We propose that before term labor, chemokines secreted as a result of mechanical stretch of the uterine walls by the growing ...
Adam Boros-Rausch +4 more
doaj +2 more sources
Deciphering the Epigenetic Code of Cardiac Myocyte Transcription
Circulation Research, 2015 Sebastian Preissl +2 more
exaly +2 more sources
Cells, 2022 Cells actively sense differences in topology, matrix elasticity and protein composition of the extracellular microenvironment and adapt their function and morphology.
Judith Brock +3 more
doaj +1 more source
A method to increase reproducibility in adult ventricular myocyte sizing and flow cytometry: Avoiding cell size bias in single cell preparations. [PDF]
, 2017 RATIONALE:Flow cytometry (FCM) of ventricular myocytes (VMs) is an emerging technology in adult cardiac research that is challenged by the wide variety of VM shapes and sizes.
Aminololama-Shakeri, Shadi +4 more
core +10 more sources
Calsarcin-2 May Play a Compensatory Role in the Development of Obese Sarcopenia
Biomedicines, 2023 Although obese sarcopenia is a major public health problem with increasing prevalence worldwide, the factors that contribute to the development of obese sarcopenia are still obscure.
Yu-Cheng Liang +7 more
doaj +1 more source
International Journal of Translational Medicine, 2023 Normal contractile function of the myocardium is essential for optimal cardiovascular health. Evaluating drug effects on cardiomyocyte function at the cellular level is difficult for long-term studies.
Leonard M. Eisenberg +4 more
doaj +1 more source
Changes in Cardiomyocyte Cell Cycle and Hypertrophic Growth During Fetal to Adult in Mammals
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 The failure of adult cardiomyocytes to reproduce themselves to repair an injury results in the development of severe cardiac disability leading to death in many cases.
Sanford P. Bishop +3 more
doaj +1 more source