Results 151 to 160 of about 78,026 (273)

Sphingosine‐1‐Phosphate Receptor Modulators for the Treatment of Ulcerative Colitis: A Narrative Review Focusing on Safety

United European Gastroenterology Journal, EarlyView.
ABSTRACT Ulcerative colitis is a chronic immune‐mediated inflammatory disease of the colon that causes considerable morbidity and increases the risk of colorectal cancer. Several targeted therapies have been developed for moderate‐to‐severe ulcerative colitis, significantly improving its management.
Massimo C. Fantini, Diego Centonze, Giovanni Giacobazzi, Silvia Benemei, Emanuele Romeo   +4 more
wiley   +1 more source

cGMP compartments in cardiac myocytes [PDF]

BMC Pharmacology, 2007
Rodolphe Fischmeister, Liliana R.V. Castro   +1 more
openaire   +2 more sources

Characterization and differentiation of myocardial remodeling using artificial intelligence‐assisted confocal Raman spectroscopy imaging

VIEW, EarlyView.
Myocardial remodeling is a key factor in heart failure. Rats were treated with ISO to induce remodeling, confirmed by echocardiography and staining. Confocal Raman spectroscopy imaging provided detailed insights into tissue architecture and the differentiation of regions.
Renxing Song, Xunyi Yin, Manlin Zhu, Xinyu Chen, Zhen Zhang, Xiaoming Lyu, Shuang Jiang, Zhehan Liu, Yuting Li, Zhaoying Zhang, Tao Ban, Yang Li   +11 more
wiley   +1 more source

Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle

FASEB BioAdvances, EarlyView.
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn, Jeongjin J. Kim, Aaron L. Slusher, Jeffrey Y. Ying, Eric Y. Zhang, Andrew T. Ludlow   +5 more
wiley   +1 more source

Foetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal myocardial deformation in normo‐oxygenated foetuses in early labour and its relationship with intrapartum outcomes. Design Single centre prospective study. Setting Referral tertiary maternity unit. Population Uncomplicated singleton term pregnancies in early labour.
Andrea Dall'Asta, Chiara Melito, Beatrice Valentini, Mariagrazia Capurso, Maria Teresa Baffa, Olga Patey, Basky Thilaganathan, Tullio Ghi   +7 more
wiley   +1 more source

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN‐2‐Mediated Changes

Aging Cell, EarlyView.
Changes in mitochondrial structure and dynamics during aging provide a mechanism for the development of age‐related sarcopenia, a condition characterized by muscle mass loss. Through the creation of three‐dimensional models of mitochondria from quadriceps muscle tissue taken from old and young humans, a loss in mitochondrial complexity was observed to ...
Estevão Scudese, Andrea G. Marshall, Zer Vue, Vernat Exil, Benjamin I. Rodriguez, Mert Demirci, Larry Vang, Edgar Garza López, Kit Neikirk, Bryanna Shao, Han Le, Dominique Stephens, Duane D. Hall, Rahmati Rostami, Taylor Rodman, Kinuthia Kabugi, Jian‐qiang Shao, Margaret Mungai, Salma T. AshShareef, Innes Hicsasmaz, Sasha Manus, Celestine N. Wanjalla, Aaron Whiteside, Revathi Dasari, Clintoria R. Williams, Steven M. Damo, Jennifer A. Gaddy, Brian Glancy, Estélio Henrique Martin Dantas, André Kinder, Ashlesha Kadam, Dhanendra Tomar, Fabiana Scartoni, Matheus Baffi, Melanie R. McReynolds, Mark A. Phillips, Anthonya Cooper, Sandra A. Murray, Anita M. Quintana, Nelson Wandira, Okwute M. Ochayi, Magdalene Ameka, Annet Kirabo, Sepiso K. Masenga, Chanel Harris, Ashton Oliver, Pamela Martin, Amadou Gaye, Olga Korolkova, Vineeta Sharma, Bret C. Mobley, Prasanna Katti, Antentor Hinton   +52 more
wiley   +1 more source

Rare but relevant: Hydrocarbons and sudden sniffing syndrome

Addiction, EarlyView.
Abstract Inhaled hydrocarbon‐associated sudden collapse (IHASC), often referred to as ‘sudden sniffing death syndrome’ is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during
Ingrid Berling, Geoffrey Kennedy Isbister   +1 more
wiley   +1 more source

Unlocking the potential of cardiac TRP channels using knockout mice models. [PDF]

Front Physiol
Kulkarni K, Walton RD, Chaigne S.
europepmc   +1 more source

Cardiac Magnetic Resonance Elastography: Why Multiplex Approaches Hold the Key to Clinical Translation

Journal of Magnetic Resonance Imaging, EarlyView.
Johannes Castelein, Ronald J. H. Borra, Adam E. Hansen   +2 more
wiley   +1 more source

Suspected marsh mallow (Malva parviflora) toxicosis in ponies—Case cluster including an asymptomatic survivor

Australian Veterinary Journal, EarlyView.
There is limited published information on Malva parviflora toxicosis in horses. Four previously reported cases all resulted in death or euthanasia. The aim of this cluster investigation was to describe historical, clinical and clinicopathological findings of four ponies with suspected M.
J Bauquier, C Takahashi, C Rosales, J Pitt   +3 more
wiley   +1 more source