Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells [PDF]
Inflammation and RegenerationCa2+ signals play a crucial role in maintaining cardiovascular homeostasis, including regulation of the heartbeat, blood pressure, and adaptation to changes in the external environment.
Tsukasa Koide +5 more
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Neural network tissue and myocytes co-culture system reveals effects of different myocytes on postnatal development of spinal cord neural network [PDF]
Cellular and Molecular Life SciencesSUMMARY The interaction between spinal cord neural networks and myocytes in postnatal mammals plays a crucial role in development, and the neural regulation of motor and visceral functions. Here, spinal cord neural network tissue (SC-NNT) was constructed
Shangbin Yang +17 more
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Defining cardiac cell populations and relative cellular composition of the early fetal human heart
PLoS ONE, 2022 While the adult human heart is primarily composed of cardiomyocytes, fibroblasts, endothelial and smooth muscle cells, the cellular composition during early development remains largely unknown.
Jennifer M. Dewing +3 more
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Frontiers in Pharmacology, 2021 Diabetic gastroparesis (DGP) is a common complication of diabetes mellitus (DM). Our previous study suggested that the expression of the long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is closely related to ...
Yanjuan Wang +7 more
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Nitric oxide mediates stretch-induced Ca2+ release via activation of phosphatidylinositol 3-kinase-Akt pathway in smooth muscle. [PDF]
PLoS ONE, 2008 Hollow smooth muscle organs such as the bladder undergo significant changes in wall tension associated with filling and distension, with attendant changes in muscle tone. Our previous study indicated that stretch induces Ca(2+) release occurs in the form
Bin Wei +9 more
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Biochemical and molecular-physiological aspects of the nitric oxide action in the utera [PDF]
The Ukrainian Biochemical Journal, 2021 The sources of the nitric oxide (NO) formation in the uterus and the dynamics of changes in its content in different periods of organ functioning in human and animals are analyzed.
H. V. Danylovych, Yu. V. Danylovych
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Immunocytochemical characteristics of submucosal uterine myomas [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. Myomas of the uterus, the most common benign tumors, have been studied for decades from the aspects of different basic and clinical disciplines. Despite this fact, their pathogenesis is still poorly understood.
Mladenović-Mihailović Aleksandra +5 more
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Key role for Kv11.1 (ether‐a‐go‐go related gene) channels in rat bladder contractility
Physiological Reports, 2023 In addition, to their established role in cardiac myocytes and neurons, ion channels encoded by ether‐a‐go‐go‐related genes (ERG1‐3 or kcnh2,3 and 6) (kcnh2) are functionally relevant in phasic smooth muscle.
Vincenzo Barrese +7 more
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The World Journal of Men's Health, 2023 Purpose: We aimed to investigate the mechanism of phenotypic transformation of corporal cavernosum smooth muscle cells (CCSMCs) under hypoxic conditions in vitro.
Xiongcai Zhou +6 more
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Scientific Reports, 2023 Cell-based therapy is a major focus for treatment of stress urinary incontinence (SUI). However, derivation of primary cells requires tissue biopsies, which often have adverse effects on patients. A recent study used human induced pluripotent stem cells (
M. Kibschull +6 more
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