Results 41 to 50 of about 34,551 (223)
A. Huxley’s equations were used to determine the mechanical properties of muscle myosin II (MII) at the molecular level, as well as the probability of the occurrence of the different stages in the actin–myosin cycle.
Yves Lecarpentier +7 more
doaj +1 more source
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks +14 more
wiley +1 more source
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source
Distribution of Major Basic Protein on Human Airway following In Vitro Eosinophil Incubation
Major basic protein (MBP) released from activated eosinophils may influence airway hyperresponsiveness (AHR) by either direct effects on airway myocytes or by an indirect effect.
Ailing Xue +3 more
doaj +1 more source
Active Movement of the Tunic in Halocynthia roretzi
Halocynthia roretzi, a solitary ascidian, can swell and deflate its solid, leather-like tunic largely, but it is not clear whether the tunic deforms actively.
Yoko KATO
doaj +1 more source
Early pathohistological changes in dysfunction of arteriovenous fistula for hemodialysis [PDF]
Background. In hemodialysis patients the most common cause of vascular access failure is neointimal hyperplasia of vascular smooth muscle cells at the venous anastomosis of arteriovenous fistulas. Case report.
Stolić Radojica +3 more
doaj +1 more source
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
Evidence For Phosphorylation-Dependent Modulation of BK Channel Activity in Vascular Smooth Muscle (VSM) Myocytes and Resistance Arteries [PDF]
VSM excitability is regulated by large conductance, calcium-activated K+ (BK) channels. We have previously reported that type I cGMP-dependent protein kinase (cGKI) phosphorylates the BK channel at key serine residues, leading to augmented BK current magnitude. Here, we investigate the cellular mechanisms regulating the temporal pattern (i.e. onset and
Kyle, Barry D. +2 more
openaire +1 more source

