Results 121 to 130 of about 32,334 (225)
Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries +2 more
wiley +1 more source
Cellular retinoic acid binding protein 2 (CRABP2), a member of a family of specific carrier proteins for Vitamin A, belongs to a family of small cytosolic lipid binding proteins.
Jing Yuan +3 more
doaj +1 more source
Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza +8 more
wiley +1 more source
Pitfalls and missing links in current understanding of 4D genomes
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley +1 more source
Skeletal muscle atrophy is a critical component of the ageing process. Age-related muscle wasting is due to disrupted muscle protein turnover, a process mediated in part by the ubiquitin proteasome pathway (UPP).
Renae Jane Stefanetti +5 more
doaj +1 more source
A hedgehog-like signal is involved in slow muscle differentation in Sepia officinalis [PDF]
In the tentacle of Sepia officinalis, smooth-like, helical and cross-striated fibres deriving from different populations of myoblasts are present. Myoblasts appear at different times during the development and express two muscle-specific transcription ...
A Grimaldi +5 more
doaj
ABSTRACT By 2050, the global population is projected to reach ~10 billion, leading to 50% increase in food demand. This growth will place immense pressure on agricultural systems that are already struggling with the impacts of climate change and resource depletion.
Chaquayla Katam +3 more
wiley +1 more source
MyoD and the regulation of myogenesis by helix-loop-helix proteins. [PDF]
S J, Tapscott, H, Weintraub
openaire +2 more sources
The fabricated cell scaffolds in this work facilitated enhanced satellite cell infiltration, preserved their differentiation potential, and promoted the initiation of myogenesis. ABSTRACT Stem cells are usually sensitive to extracellular matrix (ECM), and an effective synthetic ECM to mimic there in vivo growth surroundings is always desired.
Qun Chen +5 more
wiley +1 more source
Regulation of Pax7 protein levels by caspase-3 and proteasome activity in differentiating myoblasts
The transcription factor Pax7 negatively regulates the activity of the muscle regulatory transcription factor MyoD, preventing muscle precursor cells from undergoing terminal differentiation.
Hugo C Olguín
doaj

