Results 121 to 130 of about 32,334 (225)

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries   +2 more
wiley   +1 more source

CRABP2 promotes myoblast differentiation and is modulated by the transcription factors MyoD and Sp1 in C2C12 cells.

open access: yesPLoS ONE, 2013
Cellular retinoic acid binding protein 2 (CRABP2), a member of a family of specific carrier proteins for Vitamin A, belongs to a family of small cytosolic lipid binding proteins.
Jing Yuan   +3 more
doaj   +1 more source

Heme Metabolism‐Derived Carbon Monoxide Regulates Skeletal Muscle Function

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Heme oxygenases, HO‐1 (Hmox1) and HO‐2 (Hmox2), regulate skeletal muscle homeostasis by degrading heme and generating carbon monoxide (CO), a bioactive signalling molecule. Although HO‐1 is known to influence muscle fibre composition and mitochondrial function, the role of HO‐2 in activity‐dependent neuromuscular plasticity remains ...
Rodrigo W. Alves de Souza   +8 more
wiley   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise

open access: yesFrontiers in Physiology, 2014
Skeletal muscle atrophy is a critical component of the ageing process. Age-related muscle wasting is due to disrupted muscle protein turnover, a process mediated in part by the ubiquitin proteasome pathway (UPP).
Renae Jane Stefanetti   +5 more
doaj   +1 more source

A hedgehog-like signal is involved in slow muscle differentation in Sepia officinalis [PDF]

open access: yesInvertebrate Survival Journal, 2007
In the tentacle of Sepia officinalis, smooth-like, helical and cross-striated fibres deriving from different populations of myoblasts are present. Myoblasts appear at different times during the development and express two muscle-specific transcription ...
A Grimaldi   +5 more
doaj  

Next‐Generation Sustainable Food Production Through Integrative Biotechnology, AI, and Climate‐Resilient Innovations

open access: yesFood and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT By 2050, the global population is projected to reach ~10 billion, leading to 50% increase in food demand. This growth will place immense pressure on agricultural systems that are already struggling with the impacts of climate change and resource depletion.
Chaquayla Katam   +3 more
wiley   +1 more source

Hemoglobin Nanofibrils as Electrospun Cell Scaffolds to Enhance Primary Satellite Cell Proliferation and Differentiation for Muscle Regeneration

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
The fabricated cell scaffolds in this work facilitated enhanced satellite cell infiltration, preserved their differentiation potential, and promoted the initiation of myogenesis. ABSTRACT Stem cells are usually sensitive to extracellular matrix (ECM), and an effective synthetic ECM to mimic there in vivo growth surroundings is always desired.
Qun Chen   +5 more
wiley   +1 more source

Regulation of Pax7 protein levels by caspase-3 and proteasome activity in differentiating myoblasts

open access: yesBiological Research, 2011
The transcription factor Pax7 negatively regulates the activity of the muscle regulatory transcription factor MyoD, preventing muscle precursor cells from undergoing terminal differentiation.
Hugo C Olguín
doaj  

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