Results 101 to 110 of about 32,334 (225)

Exercise training to preserve vitality capacity in ageing

Experimental Physiology, EarlyView.
Abstract Ageing is an escalating global health issue, with the World Health Organization (WHO) reporting that one in six individuals will be 60 years or older by the year 2030. Therefore, understanding the mechanisms of complex biological ageing processes and associated healthcare challenges has become increasingly important.
Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford   +12 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

What determines growth potential and juvenile quality of farmed fish species? [PDF]

, 2013
Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
Alami-Durante, Alami-Durante, Albalat, Albors, Almuly, Almuly, Almuly, Andersen, Aragão, Ayala, Bai, Barresi, Baxendale, Betancor, Bizuayehu, Blaxter, Bodine, Booman, Bouraoui, Bouza, Bower, Bowman, Brent, Brix, Brodeur, Brooks, Buckingham, Bustin, Cade, Calduch-Giner, Calvo, Campinho, Campos, Campos, Campos, Canario, Canas, Carroll, Cerda, Cerda, Chatziplis, Chen, Chistiakov, Ciechanover, Cleveland, Cleveland, Codina, Cole, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Cruz-Garcia, De-Santis, Delbarre-Ladrat, Devoto, Dionísio, Dong, Douglas, Douglas, Dumont, Edvardsen, Engrola, Engrola, Erbay, Fauconneau, Fauconneau, Felip, Fernandes, Fernandes, Fernandes, Fernandes, Ferraresso, Ferraresso, Focant, Franklin, Galloway, Galloway, Galloway, Garcia De La Serrana, Gibson, Goetz, Goll, Gomez-Requeni, Gomez-Requeni, Gracey, Greer-Walker, Groves, Guyon, Hagen, Hagen, Hall, Hamre, Hayes, Hietakangas, Hinits, Hollway, Houlihan, Houlihan, Houlihan, Houlihan, Houlihan, Hubert, Hurling, Infante, Jackman, Jantzen, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Kamler, Kang, Kiørboe, Kloosterman, Koumans, Krasnov, Kuhl, Kuhl, Ladrat, Lakra, Lansard, Lecker, Liang, Link, Lopez, Lopez-Albors, Loukovitis, Louro, López-Albors, Maccatrozzo, Macqueen, Macqueen, Macqueen, Macqueen, Marschallinger, Martinez, Martinez, Martyniuk, Mascarello, Massault, Matsuoka, Merchie, Metzker, Mitter, Montserrat, Moore, Morais, Morais, Mork, Moutou, Nagasawa, Norton, Olsvik, Ostaszewska, Pajcini, Periago, Piñera, Portner, Powell, Pozios, Pérez-Sánchez, Quere, Reeds, Rehfeldt, Reid, Rescan, Rescan, Rescan, Rescan, Rowlerson, Rowlerson, Rowlerson, Roy, Roy, Saillant, Salem, Salem, Salem, Salvanes, Sanchez-Ramos, Sarropoulou, Seiliez, Seiliez, Seiliez, Shewring, Silva, Silva, Silva, Sonesson, Stears, Steinbacher, Stellabotte, Stellabotte, Stickland, Sveinsdottir, Sánchez-Ramos, Tan, Terova, Todorcevic, Valente, Valente, Valente, Veggetti, Veggetti, Vieira, Wang, Weatherley, Weil, Weinberg, West, Whitaker, Wienholds, Wienholds, Wiese, Wood, Wringe, Zane   +225 more
core   +3 more sources

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Prmt5 is a regulator of muscle stem cell expansion in adult mice. [PDF]

, 2015
Skeletal muscle stem cells (MuSC), also called satellite cells, are indispensable for maintenance and regeneration of adult skeletal muscles. Yet, a comprehensive picture of the regulatory events controlling the fate of MuSC is missing.
Braun, Thomas, Günther, Stefan, Kim, Johnny, Krüger, Marcus, Künne, Carsten, Looso, Mario, Zhang, Ting, Zhou, Yonggang   +7 more
core  

Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis [PDF]

, 1997
The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are
Adams, Aigner, Arber, Arber, Arber, Ashby, Blank, Buckingham, Chevallier, Chien, Chiquet, Chu, Condon, Connor, deLapeyriére, Duxson, Fontaine, Gatchalian, Grayson, Hauschka, Hilfer, Imaizumi-Scherrer, Jellies, Lance-Jones, Lanser, McMahon, Olson, Ontell, Rechsteiner, Ross, Schaeren-Wiemers, Schroeter, Schroeter, Shaw, Sweeney, Tucker, Witzemann, Zou   +37 more
core   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Targeting RyR Activity Boosts Antisense Exon 44 and 45 Skipping in Human DMD Skeletal or Cardiac Muscle Culture Models. [PDF]

, 2019
Systemic delivery of antisense oligonucleotides (AO) for DMD exon skipping has proven effective for reframing DMD mRNA, rescuing dystrophin expression, and slowing disease progression in animal models.
Barthélémy, Florian, Douine, Emilie D, Hsu, Christopher, Marcantonio, Eugene E, Miceli, M Carrie, Nelson, Stanley F, Wang, Richard T   +6 more
core   +1 more source