Results 91 to 100 of about 19,949 (187)
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Dnajb5, a member of the heat shock protein family, has not been previously reported to play a role in muscle differentiation. We identify Dnajb5 as a negative regulator of myogenesis via mammalian target of rapamycin (mTOR) and histone deacetylase 4 (HDAC4) signalling, functioning as a central controller of muscle growth and ...
Sun‐Hee Cho +8 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy, primarily affecting skeletal muscle and leading to premature death. Although the loss of dystrophin has long been recognised as the primary cause of the disease, no definitive cure is currently available. As a consequence, therapeutic efforts
Raffaele Epis +5 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Skeletal muscle dysfunction (SMD) is a common extrapulmonary complication of chronic obstructive pulmonary disease (COPD). Histone deacetylase 2 (HDAC2) is closely involved in the suppression of inflammatory transcription and is progressively reduced during COPD progression.
Chao Li +4 more
wiley +1 more source
A hedgehog-like signal is involved in slow muscle differentation in Sepia officinalis [PDF]
Invertebrate Survival Journal, 2007 In the tentacle of Sepia officinalis, smooth-like, helical and cross-striated fibres deriving from different populations of myoblasts are present. Myoblasts appear at different times during the development and express two muscle-specific transcription ...
A Grimaldi +5 more
doaj
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He +6 more
wiley +1 more source
Regulation of Pax7 protein levels by caspase-3 and proteasome activity in differentiating myoblasts
Biological Research, 2011 The transcription factor Pax7 negatively regulates the activity of the muscle regulatory transcription factor MyoD, preventing muscle precursor cells from undergoing terminal differentiation.
Hugo C Olguín
doaj
MyoD and the regulation of myogenesis by helix-loop-helix proteins. [PDF]
Journal of Clinical Investigation, 1991 S J, Tapscott, H, Weintraub
openaire +2 more sources
A Myocyte‐Enriched Long Non‐Coding RNA NRMLncR Enhances Myogenesis in Mouse
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.We identified a novel myocyte‐enriched, Notch‐repressed myogenic lncRNA, NRMLncR, that is induced by myogenic regulatory factors (MRFs) during myogenic progression in mouse. NRMLncR localizes to cytoplasmic and nuclear compartments, associates with the RNA‐binding protein CUGBP Elav‐like family member 1 (CELF1), and is linked to neighboring gene Tbx1 ...
Yufen Li +12 more
wiley +1 more source
针刺研究, 2019 Objective To explore the effect of electroacupuncture(EA)serum on expression of myogenic differentiation antigen(Myod)and autophagy-related protein Beclin 1 in cultured muscle satellite cells of rats under starvation conditions.MethodsThe primary ...
LIU Tong +8 more
doaj
The myoblast methylome: multiple types of associations with chromatin and transcription
EpigeneticsEpigenetic changes are implicated in development, repair, and physiology of postnatal skeletal muscle (SkM). We generated methylomes for human myoblasts (SkM progenitor cells) and determined myoblast differentially methylated regions (DMRs) for ...
Sagnik Sen +8 more
doaj +1 more source