Results 91 to 100 of about 32,334 (225)

Sinensetin regulates age-related sarcopenia in cultured primary thigh and calf muscle cells

BMC Complementary and Alternative Medicine, 2019
Background Sarcopenia, the decline of skeletal muscle tissue attributed to primary aging is a major concern in older adults. Flavonoids might have potential benefits by modulating the regulation of satellite cells, thus preventing muscle loss. Sinensetin
Jin-A Kim, Seong Min Kim, Sang Eun Ha, Preethi Vetrivel, Venu Venkatarame Gowda Saralamma, Eun Hee Kim, Gon Sup Kim   +6 more
doaj   +1 more source

Efficient transgene expression system using a cumate-inducible promoter and Cre-loxP recombination in avian cells [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective Transgenic technology is widely used for industrial applications and basic research. Systems that allow for genetic modification play a crucial role in biotechnology for a number of purposes, including the functional analysis of specific genes ...
Tae Sub Park, Si Won Kim, Jeong Hyo Lee
doaj   +1 more source

Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy [PDF]

, 2015
Spinal and bulbar muscular atrophy (SBMA) is characterized by loss of motoneurons and sensory neurons, accompanied by atrophy of muscle cells. SBMA is due to an androgen receptor containing a polyglutamine tract (ARpolyQ) that misfolds and aggregates ...
Aggarwal, Tanya, Cicardi, Maria Elena, Crippa, Valeria, Cristofani, Riccardo, Galbiati, Mariarita, Giorgetti, Elisa, Lieberman, Andrew P., Meroni, Marco, Messi, Elio, Milioto, Carmelo, Pennuto, Maria, Piccolella, Margherita, Polanco, Maria Josefa, Poletti, Angelo, Rocchi, Anna, Rusmini, Paola   +15 more
core   +2 more sources

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Coordinate actions of BMPs, Wnts, Shh and noggin mediate patterning of the dorsal somite [PDF]

, 1997
Shortly after their formation, somites of vertebrate embryos differentiate along the dorsoventral axis into sclerotome, myotome and dermomyotome.
Bronner-Fraser, Marianne, Marcelle, Christophe, Stark, Michael R.   +2 more
core  

Suv4-20h Histone Methyltransferases Promote Neuroectodermal Differentiation by Silencing the Pluripotency-Associated Oct-25 Gene [PDF]

, 2013
Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression. During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted
A Barski, A Magklara, AK Teo, Anne C. Ferguson-Smith, BM Lee, CD Rogers, CS Hinkley, Dario Nicetto, E Meshorer, E Meshorer, G Schotta, G Schotta, GM Morrison, Gunnar Schotta, H Niwa, I Munoz-Sanjuan, JH Lee, Julia Jung, K Takebayashi-Suzuki, L Yang, LA Banaszynski, LA Boyer, LA Boyer, M Hemberger, M Snir, M Tachibana, M Thomson, Matthias Hahn, N Singhal, NL Vastenhouw, NS Christophersen, P Kapoor-Vazirani, R Cao, R David, Ralph A. W. Rupp, RC Akkers, Robert David, S Dambacher, S Rea, SA Blythe, SC Dillon, SR Bhaumik, SV Saladi, T Hashimshony, T Hollemann, T Kwon, TD Schneider, Tobias D. Schneider, Tobias Straub, TS Mikkelsen, U Hellsten, VL Biron, WA Harris, Y Cao, Y Cao, Y Cao, Y Zhang, Z Li   +57 more
core   +3 more sources

Basic helix‐loop‐helix protein MyoD displays modest DNA binding specificity

FEBS Letters, 1996
The expression of MyoD can activate muscle specific genes and myogenic differentiation in many cell types. The hypothesis that the DNA binding specificity of MyoD is responsible for its biological specificity was tested. Homodimers of MyoD bind to E‐box containing DNA with high affinity, but do not form stable and well defined complexes with ...
Künne AG, Meierhans D, Allemann RK
openaire   +3 more sources

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

IMPACT OF L-CARNITINE SUPPLEMENTATION ON GROWTH OF BROILER CHICKEN THROUGH DETERMINATION OF CHANGES IN THE EXPRESSION OF CAT2, MYOD AND MYF5 GENES

Slovenian Veterinary Research, 2019
This study explored the impact of supplementation of L- carnitine on the performance of broiler chicken, biochemical parameters and expression of cationic amino acid transporter (CAT2), myogenic determining factor (MYOD) and myogenic factor 5 (MYF5 ...
Tarek Abouzed, Doaa Dorghamm, Khaled Kahilo, Azza Elkattawy, Eldsokey Nassef, Hanan El-sawy   +5 more
doaj   +1 more source

Pbx Marks Genes for Activation by MyoD Indicating a Role for a Homeodomain Protein in Establishing Myogenic Potential [PDF]

Molecular Cell, 2004
Skeletal muscle differentiation is initiated by the transcription factor MyoD, which binds directly to the regulatory regions of genes expressed during skeletal muscle differentiation and initiates chromatin remodeling at specific promoters. It is not known, however, how MyoD initially recognizes its binding site in a chromatin context.
Berkes, Charlotte A., Bergstrom, Donald A., Penn, Bennett H., Seaver, Karen J., Knoepfler, Paul S., Tapscott, Stephen J.   +5 more
openaire   +2 more sources