Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities
MedComm, Volume 7, Issue 5, May 2026.This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng +8 more
wiley +1 more source
Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neuronal differentiation of P19 embryonal carcinoma cells [PDF]
, 1992 MASH1 and MASH2, mammalian homologues of the Drosophila neural determination genes achaete-scute, are members of the basic helix-loop-helix (bHLH) family of transcription factors.
Anderson, David J. +3 more
core
Generation of both an shRNA-resistant MEF2A over expression construct and a dominant negative construct in adenovirus for rescue and knockout experiments in muscle [PDF]
, 2015 The Myocyte Enhancer Factor-2, or MEF2, transcription factor family is necessary for the differentiation and regeneration of both skeletal and cardiac muscle tissue.
Comeau, Kathryn Marie
core +1 more source
Tat-MyoD fused proteins, together with C2c12 conditioned medium, are able to induce equine adult mesenchimal stem cells towards the myogenic fate [PDF]
, 2017 Gomiero, Chiara +5 more
core +1 more source
The myoblast methylome: multiple types of associations with chromatin and transcription
EpigeneticsEpigenetic changes are implicated in development, repair, and physiology of postnatal skeletal muscle (SkM). We generated methylomes for human myoblasts (SkM progenitor cells) and determined myoblast differentially methylated regions (DMRs) for ...
Sagnik Sen +8 more
doaj +1 more source
Journal of Cachexia, Sarcopenia and MuscleBackground Skeletal muscle injury is one of the most common sports injuries; if not properly treated or not effective rehabilitation treatment after injury, it can be transformed into chronic cumulative injury.
Mao‐yuan Wang +6 more
doaj +1 more source
康复学报ObjectiveTo observe the effect and its mechanism of massage manipulation on the repair and regeneration of skeletal muscle overuse injury in rats based on Wnt/β-catenin signaling pathway.MethodsA total of 42 SD rats were randomly divided into blank group,
DUAN Miaomiao +5 more
doaj
A hedgehog-like signal is involved in slow muscle differentation in Sepia officinalis (Mollusca)
Invertebrate Survival Journal, 2007 In the tentacle of Sepia officinalis, smooth-like, helical and cross-striated fibres deriving from different populations of myoblasts are present. Myoblasts appear at different times during the development and express two muscle-specific transcription ...
A Grimaldi +5 more
doaj
Klhl31 is assocaited with skeletal myogenesis and its expression is regulated by myogenic signals and Myf-5 [PDF]
, 2009 Adams +42 more
core +1 more source
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
, 2000 Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J. +8 more
core