Results 101 to 110 of about 1,180 (165)
, 2017 Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the third leading cause of cancer related death. Therapeutic options remain very limited and are still based on classical chemotherapies.
Durieux, Florence +17 more
core
, 2019 International audienceDysferlin has been implicated in acute membrane repair processes, whereas myoferlin's activity is maximal during the myoblast fusion stage of early skeletal muscle cell development.
Anne M. Rice +17 more
core +1 more source
Breast Cancer Cell Adhesion Strength Following Lentivirus-Mediated Myoferlin Depletion [PDF]
, 2011 This project has earned the author the BME Senior Research Achievement AwardThe purpose of this project was to quantify the effect of lentiviral-based knockdown of myoferlinon the adhesion and spreading of MDA-MB-231 human breast cancer cells ...
Bechel, Meagan
core
Myoferlin knockdown induces changes in cell detachment and apoptosis but not inflammation.
, 2012 16HBE cells were treated with control media (con), transfection control (TF con), scrambled siRNA (S), or myoferlin siRNA at 50 nM, 75 nM and 100 nM for 72 h.
Tillie-Louise Hackett (92016) +3 more
core +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths worldwide. Radiotherapy alone or combined with chemotherapy is a therapeutic modality implemented in different circumstances (neoadjuvant, adjuvant, symptomatic)
Gullo, Charlotte +8 more
core
Myoferlin depletion attenuates MMP1 expression and collagen I invasion capacity of MDA-MB-231 cells.
, 2012 (A) Representative (n = 3) immunoblotting results of secreted MMP1 in 24 h serum starved supernatant of MDA-MB-231 lentiviral control (LTV-ctrl) and myoferlin knockdown (MYOF-KD) cells. Recombinant human matrix metalloproteinase-1 was used as a standard.
Samir Ghadiali (155520) +5 more
core +1 more source
Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer
, 2019 Pancreatic cancer is the 7th most common cause of cancer mortality in the world. It is predicted to become the second leading cause of cancer-related death in 2030. Myoferlin is a 230 kDa protein overexpressed in pancreatic cancer.
Wissocq, Tom +5 more
core
Expression of EMT markers following myoferlin depletion in MDA-MB-231 cells.
, 2012 (A) Representative immunoblots (n = 3) of select EMT markers in lentiviral control (LTV-ctrl) and myoferlin depleted (MYOF-KD) cells serum-starved for 24 h.
Samir Ghadiali (155520) +5 more
core +1 more source
A novel oncogenic protein in the Progranulin\EphA2 axis: the role of Myoferlin in bladder cancer
, 2022 reservedThe growth factor progranulin plays a key role in bladder cancer by promoting cell motility and invasion. Until recently, the progranulin signaling receptor remained unknown precluding a full comprehension of progranulin action in cancer.
RUGGIERO, VALENTINA
core
, 2012 /Western blot for the myoferlin protein in Dysf prmd and TgMyof/Dysf prmd FDB muscles shows the overexpression of myoferlin in TgMyof/Dysf prmd (results for 2 animals are shown for each muscle and condition). A-Actin was used as loading control.
Carinne Roudaut (162223) +13 more
core +1 more source