Advances in separation and identification of biologically important milk proteins and peptides
ELECTROPHORESIS, Volume 45, Issue 1-2, Page 101-119, January 2024.Abstract Milk is a rich source of biologically important proteins and peptides. In addition, milk contains a variety of extracellular vesicles (EVs), including exosomes, that carry their own proteome cargo. EVs are essential for cell–cell communication and modulation of biological processes. They act as nature carriers of bioactive proteins/peptides in
Miroslava Stastna
wiley +1 more source
Myoferlin knockdown induces changes in cell detachment and apoptosis but not inflammation. [PDF]
, 2012 16HBE cells were treated with control media (con), transfection control (TF con), scrambled siRNA (S), or myoferlin siRNA at 50 nM, 75 nM and 100 nM for 72 h.
Tillie-Louise Hackett (92016) +3 more
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HRB Open Research, 2018 Background: In Duchenne muscular dystrophy, primary abnormalities in the membrane cytoskeletal protein dystrophin trigger the loss of sarcolemmal linkage between the extracellular matrix component laminin-211 and the intracellular cortical actin membrane
Sandra Murphy +4 more
doaj +1 more source
Modulation de la radiosensibilité par ciblage pharmacologique de la myoferline dans des lignées cellulaires cancéreuses du pancréas humain [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths worldwide. Radiotherapy alone or combined with chemotherapy is a therapeutic modality implemented in different circumstances (neoadjuvant, adjuvant, symptomatic)
Gullo, Charlotte +8 more
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Myoferlin depletion attenuates MMP1 expression and collagen I invasion capacity of MDA-MB-231 cells. [PDF]
, 2012 (A) Representative (n = 3) immunoblotting results of secreted MMP1 in 24 h serum starved supernatant of MDA-MB-231 lentiviral control (LTV-ctrl) and myoferlin knockdown (MYOF-KD) cells. Recombinant human matrix metalloproteinase-1 was used as a standard.
Samir Ghadiali (155520) +5 more
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Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [PDF]
, 2019 Pancreatic cancer is the 7th most common cause of cancer mortality in the world. It is predicted to become the second leading cause of cancer-related death in 2030. Myoferlin is a 230 kDa protein overexpressed in pancreatic cancer.
Wissocq, Tom +5 more
core
Expression of EMT markers following myoferlin depletion in MDA-MB-231 cells. [PDF]
, 2012 (A) Representative immunoblots (n = 3) of select EMT markers in lentiviral control (LTV-ctrl) and myoferlin depleted (MYOF-KD) cells serum-starved for 24 h.
Samir Ghadiali (155520) +5 more
core +1 more source
The membrane trafficking protein myoferlin is a novel interactor of p97 [PDF]
p97 uses the energy of ATP hydrolysis to unfold and thereby segregate proteins. It is involved in various cellular processes such as proteasomal degradation, DNA damage repair, autophagy, and endo-lysosomal trafficking. The specificity for these processes is controlled by more than 30 regulatory cofactors.
openaire +1 more source
A novel oncogenic protein in the Progranulin\EphA2 axis: the role of Myoferlin in bladder cancer [PDF]
, 2022 reservedThe growth factor progranulin plays a key role in bladder cancer by promoting cell motility and invasion. Until recently, the progranulin signaling receptor remained unknown precluding a full comprehension of progranulin action in cancer.
RUGGIERO, VALENTINA
core
Myoferlin overexpression improves sarcolemmal repair after laser wounding but do not improve muscle histology. A [PDF]
, 2012 /Western blot for the myoferlin protein in Dysf prmd and TgMyof/Dysf prmd FDB muscles shows the overexpression of myoferlin in TgMyof/Dysf prmd (results for 2 animals are shown for each muscle and condition). A-Actin was used as loading control.
Carinne Roudaut (162223) +13 more
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