Results 81 to 90 of about 1,884 (173)
Clinical and Translational Allergy, Volume 15, Issue 6, June 2025.Abstract Background Hereditary angioedema (HAE) is a rare, autosomal dominantly inherited disease characterised by mucocutaneous oedema attacks. Vasoactive mediators and the endothelium play an important role in the pathogenesis of HAE. We aimed to evaluate the endothelial dysfunction in HAE. Methods The study included 35 C1 inhibitor deficient (C1‐INH)
Gokce Gul Atay Sensoy +7 more
wiley +1 more source
Myoferlin is required for insulin‐like growth factor response and muscle growth
The FASEB Journal, 2009 ABSTRACT Insulin‐like growth factor (IGF) is a potent stimulus of muscle growth. Myoferlin is a membraneassociated protein important for muscle development and regeneration. Myoferlin‐null mice have smaller muscles and defective myoblast fusion.
Alexis R, Demonbreun +6 more
openaire +3 more sources
Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network [PDF]
, 2015 The dynamics of filopodia interacting with the surrounding extracellular matrix (ECM) play a key role in various cell-ECM interactions, but their mechanisms of interaction with the ECM in 3D environment remain poorly understood. Based on first principles,
Asada, Harry +4 more
core +3 more sources
, 2015 BACKGROUND: Hypertension is a complex disease with many contributory genetic and environmental factors. We aimed to identify common targets for therapy by gene expression profiling of a resistance artery taken from animals representing two different ...
Brackenbury, Therese +8 more
core +1 more source
The Journal of Dermatology, Volume 52, Issue 2, Page 256-269, February 2025.Abstract Hereditary angioedema (HAE) symptoms can vary greatly. Disease burden evaluation is essential for providing adequate treatments for patients. Patient‐reported outcome measures (PROMs), including the 12‐Item Short Form Health Survey (SF‐12), the Angioedema Quality of Life (AE‐QoL), the Hospital Anxiety and Depression Scale (HADS), and the Work ...
Michihiro Hide +6 more
wiley +1 more source
Multiple testing procedures under confounding
, 2008 While multiple testing procedures have been the focus of much statistical research, an important facet of the problem is how to deal with possible confounding. Procedures have been developed by authors in genetics and statistics.
Ghosh, Debashis
core +1 more source
Mediators of Inflammation, Volume 2025, Issue 1, 2025.Background: Wilson’s disease (WD) is an abnormal copper metabolism disease. GanDouFuMu decoction (GDFMD) is a traditional Chinese medicine, whicn has shown good therapeutic effects in clinical treatment of WD liver fibrosis;but its regulatory mechanism is still unclear.
Peng Huang +10 more
wiley +1 more source
Journal of Extracellular Biology, Volume 3, Issue 11, November 2024.Abstract The promise of urinary extracellular vesicles (uEVs) in biomarker discovery is emerging. However, the characteristics and compositions of different uEV subpopulations across normal physiological and pathological states require rigorous explication.
Susannah M. Hallal +7 more
wiley +1 more source
Marine Drugs, 2019 To investigate the variation in the condition factor of the sea urchin Strongylocentrotus nudus (S. nudus), gonads were collected in May (MAY), June (JUN), and July (JUL), at the beginning (AUG-b) and end of August (AUG-e).
Wen-Hui Shang +8 more
doaj +1 more source
Targeting lysosomal quality control as a therapeutic strategy against aging and diseases
Medicinal Research Reviews, Volume 44, Issue 6, Page 2472-2509, November 2024.Abstract Previously, lysosomes were primarily referred to as the digestive organelles and recycling centers within cells. Recent discoveries have expanded the lysosomal functional scope and revealed their critical roles in nutrient sensing, epigenetic regulation, plasma membrane repair, lipid transport, ion homeostasis, and cellular stress response ...
Yuchen He +6 more
wiley +1 more source