Results 71 to 80 of about 1,281 (134)

Mitochondrial fusion–fission dynamics and its involvement in colorectal cancer

Molecular Oncology, Volume 18, Issue 5, Page 1058-1075, May 2024.
Disruption of the mitochondrial fusion–fission dynamics balance plays a dual role in colorectal cancer development. Mitochondrial fission promotes cancer cell proliferation, invasion, migration, and chemoresistance, while excessive fission induces apoptosis.
Zihong Wu, Chong Xiao, Fang Li, Wenbo Huang, Fengming You, Xueke Li   +5 more
wiley   +1 more source

Chemical crosslinking analysis of β-dystroglycan in dystrophin-deficient skeletal muscle [version 2; peer review: 2 approved]

HRB Open Research, 2018
Background: In Duchenne muscular dystrophy, primary abnormalities in the membrane cytoskeletal protein dystrophin trigger the loss of sarcolemmal linkage between the extracellular matrix component laminin-211 and the intracellular cortical actin membrane
Sandra Murphy, Margit Zweyer, Rustam R. Mundegar, Dieter Swandulla, Kay Ohlendieck   +4 more
doaj   +1 more source

The role of myoferlin and dysferlin in lung epithelial cell membrane functions and lung cancer

, 2015
Lung cancer is the deadliest cancer in the world. Almost all lung cancers originate from epithelial tissues within the lung. Lung epithelium provides a barrier to inhaled particulate matter and pathogens; hence, maintaining the normal epithelial ...
Leung, Suk Kei
core   +1 more source

Managing Diagnosis, Treatment, and Burden of Disease in Hereditary Angioedema Patients with Normal C1-Esterase Inhibitor

Journal of Asthma and Allergy, 2023
Douglas Jones,1 Heidi Zafra,2 John Anderson3 1Rocky Mountain Allergy, Tanner Clinic, Layton, UT, USA; 2Division of Allergy and Clinical Immunology, Medical College of Wisconsin, Milwaukee, WI, USA; 3AllerVie Health, Birmingham, AL, USACorrespondence ...
Jones D, Zafra H, Anderson J
doaj  

Modulation de la radiosensibilité par ciblage pharmacologique de la myoferline dans des lignées cellulaires cancéreuses du pancréas humain

Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths worldwide. Radiotherapy alone or combined with chemotherapy is a therapeutic modality implemented in different circumstances (neoadjuvant, adjuvant, symptomatic)
Gullo, Charlotte, Peiffer, Raphaël, Colin, Gilles, Coucke, Philippe, Boumahd, Yasmine, Agirman, Ferman, Maloujahmoum, Naïma, Bellahcene, Akeila, Peulen, Olivier   +8 more
core   +1 more source

Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Investigation of STAT3 involvement.

, 2022
Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths worldwide. Myoferlin is a protein implicated in membrane fusion and in receptor recycling. It allows the formation of vesicles for the trafficking in cells.
Gullo, Charlotte, Peiffer, Raphaël, Boumahd, Yasmine, Rademaker, Gilles, Agirman, Ferman, Maloujahmoum, Naïma, Bellahcene, Akeila, Peulen, Olivier, Anania, Sandy   +8 more
core  

Contribution towards understanding the role of Myoferlin during breast cancer progression

, 2014
Contribution Towards Understanding the Role of Myoferlin During Breast Cancer ProgressionMyoferlin is a member of the ferlin protein family that has key physiological functions in plasma membrane fusion, repair and endocytosis events.
Blomme, Arnaud
core  

Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer

, 2017
International audienceMyoferlin is a multiple C2-domain-containing protein that regulates membrane repair, tyrosine kinase receptor function and endocytosis in myoblasts and endothelial cells.
Bellahcène, A, Le Goff, C, de Tullio, P, Müller, R., Lifrange, E, Goldman, S, Blomme, A, Doumont, G, Castronovo, V, Cusumano, P, Turtoi, A, Di Valentin, E, Yokobori, T, Delvenne, P, Peulen, O, Boutry, S., Cavalier, E., Costanza, B, Mouithys-Mickalad, A, De Pauw, E., Boutry, Sébastien, Sherer, F, Gofflot, S, Jouret, F, Thiry, M., Van Simaeys, G, Nishiyama, M, Hirano, T.   +27 more
core   +2 more sources

Dynamic distribution of mud crab reovirus (MCRV) and haemolymph transcriptome analysis in experimentally infected mud crab (Scylla paramamosain)

Aquaculture Reports
As a commercially valuable crustacean species in mariculture systems, mud crab (Scylla paramamosain) has a broad geographical distribution across intertidal zones of the Indo-Pacific region, particularly in Southeast Asian.
Yuhang Zhan, Weijia Zhang, Michaël Bekaert, Ronghua Li, Suming Zhou, Xiaona Zhang, Chunlin Wang, Changkao Mu, Herve Migaud, Weiwei Song   +9 more
doaj   +1 more source

Modulation de la radiosensibilité des cellules pancréatiques cancéreuses par le ciblage pharmacologique de la myoferline.

, 2023
Pancreatic ductal adenocarcinoma (PDAC) will become the second leading cause of cancer-related deaths by 2030. Myoferlin is a protein involved in membrane fusion and in membrane receptors recycling and is overexpressed in PDAC where it was reported to be
Gullo, Charlotte, Peiffer, Raphaël, Colin, Gilles, Coucke, Philippe, Boumahd, Yasmine, Agirman, Ferman, Maloujahmoum, Naïma, Bellahcene, Akeila, Peulen, Olivier   +8 more
core