Recent Advances in Nanotechnology-Based Approaches for Ferroptosis Therapy and Imaging Diagnosis in Pancreatic Cancer. [PDF]
PharmaceuticsYang X, Luo W, Wang Y, Du Y, Yu R.
europepmc +1 more source
Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes
Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytesopenaire
c-Met and EPHA7 Receptor Tyrosine Kinases Are Related to Prognosis in Clear Cell Renal Cell Carcinoma: Focusing on the Association with Myoferlin Expression [PDF]
Cancers, 2022 Receptor tyrosine kinases (RTKs) are important targets for clear cell renal cell carcinoma (ccRCC) treatment. Myoferlin is a strong regulator of RTKs. To identify myoferlin-associated RTKs and their prognostic implications in ccRCC, we investigated the ...
Minsun Jung +2 more
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Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics’ Machinery in Pancreas Cancer Cells [PDF]
Cancers, 2020 Pancreas ductal adenocarcinoma is one of the deadliest cancers where surgery remains the main survival factor. Mitochondria were described to be involved in tumor aggressiveness in several cancer types including pancreas cancer. We have previously reported that myoferlin controls mitochondrial structure and function, and demonstrated that myoferlin ...
Sandy Anania +2 more
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Apatinib Degrades PD-L1 and Reconstitutes Colon Cancer Microenvironment via the Regulation of Myoferlin [PDF]
CancersBackground: For most colorectal cancer (CRC) patients, expanding the benefits of immunotherapy, particularly through blocking programmed cell death-1 (PD-1) and its ligand (PD-L1), is crucial, especially in cases with limited response to neoadjuvant therapy.
Lingying Zhao +2 more
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Expression of Myoferlin in Skeletal Muscles of Patients with Dysferlinopathy
Tohoku Journal of Experimental Medicine, 2006 Myoferlin is a novel protein of unknown function with high homology to dysferlin, the gene mutations of which cause limb girdle muscular dystrophy type 2B and Miyoshi myopathy. The myoferlin gene seems to be a candidate for the modifier, and because of the high homology to dysferlin myoferlin may work as a compensator for the absence of dysferlin in ...
Masahiko Inoue +2 more
exaly +4 more sources
International Journal of Cancer, 2016 peer reviewedPancreatic ductal adenocarcinoma is one of the most deadly forms of cancers with no satisfactory treatment to date. Recent studies have identified myoferlin, a ferlin family member, in human pancreas adenocarcinoma where its expression was ...
Arnaud Gonzalez +2 more
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Myoferline gene mutation сan be associated with recurrent angioedema
Russian Journal of Allergy, 2023Hereditary angioedema is a rare genetically determined disease characterized by the recurrent angioedema of various localizations with no response to systemic glucocorticosteroids, antihistamines. In the majority of hereditary angioedema cases C1-inhibitor level or its functional activity is decreased due to a mutation in the SERPING1 gene.
Daria S. Fomina +5 more
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Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation [PDF]
Cancers, 2019 peer reviewedPancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies with an overall survival of 5%, and is the second cause of death by cancer, mainly linked to its high metastatic aggressiveness.
Gilles Rademaker +2 more
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