Journal of Biomedical Sciences, 2013 BackgroundA recessive mutation “c” in the Mexican axolotl, Ambystoma mexicanum, results in the failure of normal heart development. In homozygous recessive embryos, the hearts do not have organized myofibrils and fail to beat. In our previous studies, we
A. Kochegarov +5 more
semanticscholar +1 more source
Thymoquinone Protects Against Cardiac Hypertrophy via PPAR‐γ/PI3K/Akt Pathway
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Thymoquinone (TQ), the principal active constituent of Nigella stativa, has demonstrated numerous biological properties and therapeutic effects on various diseases. However, its therapeutic potential against cardiac hypertrophy remains uncertain.
Rong‐bin Qiu +10 more
wiley +1 more source
Establishing laboratory standards for biological flight experiments [PDF]
The general objective of this research was to assess the effects of exposure to simulated microgravity on ultrastructural aspects of the contractile system in chicken skeletal muscle cells. This general objective had two specific experimental components:
Moriarity, Debra M., Young, Ronald B.
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Glucose and Palmitic Acid Induce Degeneration of Myofibrils and Modulate Apoptosis in Rat Adult Cardiomyocytes [PDF]
, 2001 Daniela Dyntar +6 more
openalex +1 more source
Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure
Disease Models & Mechanisms, 2013 An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction. Much remains unknown about the molecular mechanisms governing the formation of the contractile apparatus.
Kandice C. Fero +7 more
semanticscholar +1 more source
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Firstly, we determined the content of the components in the co‐products of Epimedium wine and oil. Secondly, the clinical indications of the co‐products of Epimedium wine and oil were determined by in vitro cell experiments. Finally, the in vivo animal model was used for experimental verification.
Jinling Liang +9 more
wiley +1 more source
Effects of Removal and Reconstitution of Troponin and Tropomyosin on Ca2+-Activated Tension Generation in Cardiac Myofibrils [PDF]
, 2009 Beatrice Scellini +3 more
openalex +1 more source
Thin , a Trim32 ortholog, is essential for myofibril stability and is required for the integrity of the costamere in Drosophila [PDF]
, 2012 Elisa M. LaBeau-DiMenna +5 more
openalex +1 more source
New indexes for myofibril linearity in muscle image analysis
, 2022 Ettore Rocchi +3 more
openalex +2 more sources
Sarcomere dynamics during muscular contraction and their implications to muscle function [PDF]
, 2018 This article attempts to identify the key aspects of sarcomere inhomogeneity and the dynamics of sarcomere length changes in muscle contraction experiments and focuses on understanding the mechanics of myofibrils or muscle fibres when viewed as ...
Denoth, Jachen, Telley, Ivo
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