Results 111 to 120 of about 2,944 (198)

Ets2 Is an Activity‐Dependent Transcriptional Regulator of a Fast‐Twitch Muscle Program

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Ets2 is a transcription factor rapidly (24 h) upregulated in skeletal muscle by fast 150 Hz, but not slow 20 Hz, stimulation patterns. Ets2 selectively translocates to nuclei of slow soleus muscle when stimulated by fast‐patterned, but not slow‐patterned, activity. Ets2 binds to a consensus DNA sequence in the troponin I fast intronic enhancer (TnIFIRE)
Zaheer A. Rana, Jo C. Bruusgaard, Jens R. Wendland, Ivan Winje, Ingrid M. Egner, Irina Karavanova, Einar Eftestøl, Detlef Vullhorst, Kristian Gundersen, Andres Buonanno   +9 more
wiley   +1 more source

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Scientific Reports
Previously, we showed that fluvastatin treatment induces myofibrillar damage and mitochondrial phenotypes in the skeletal muscles of Drosophila. However, the sequential occurrence of mitochondrial phenotypes and myofibril damage remains elusive.
Mohamed H. Al-Sabri, Nourhane Ammar, Stanislava Korzh, Ahmed M. Alsehli, Kimia Hosseini, Robert Fredriksson, Jessica Mwinyi, Michael J. Williams, Hadi Boukhatmi, Helgi B. Schiöth   +9 more
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, Volume 13, Issue 55, 5 October 2026.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Characterization and Selection of Contractile Actuators for Soft Robotics Operating in the Quasistatic Regime

Advanced Intelligent Systems, Volume 8, Issue 10, October 2026.
We developed methods to characterize soft contractile actuators using force–displacement measurements in the passive state and the total force in the active state and define the operational range of thermal, electrothermal, and pneumatic muscles. A graphical method enables the selection of an actuator based on the required mechanical force–displacement
Qiong Wang, Liuyang Cheng, Jeongmin Kim, Samuel Tsai, Devin Roach, Sameh Tawfick   +5 more
wiley   +1 more source

Experiment K-6-10. Effects of zero gravity on myofibril protein content and isomyosin distribution in rodent skeletal muscle [PDF]

, 1990
The purpose of this experiment was to investigate the effects of 12 days of zero gravity (0G) exposure (Cosmos 1887 Biosputnik) on the enzymatic properties, protein content, and isomyosin distribution of the myofibril fraction of the slow-twitch vastus ...
Herrick, R., Oganov, V., Baldwin, K.
core  

Overview on Epstein–Barr Virus–Host Interactions With a Focus on Host Cell Transcriptome Alterations

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT The Epstein–Barr virus (EBV) belongs to the gamma subgroup of human herpesviruses. EBV is particularly lymphotropic regarding its latency, meaning that it preferentially targets lymphocytes as its immunological niche. During the establishment of the complex virus–host relationships, the virus influences the human host cell transcriptome ...
Louise Wallot, Tim Hohmann, Urszula Hohmann, Faramarz Dehghani, Olaf Grisk, Simon Jasinski‐Bergner   +5 more
wiley   +1 more source

Fish gelatin combined with chitosan coating inhibits myofibril degradation of golden pomfret (Trachinotus blochii) fillet during cold storage

, 2016
Coating of gelatin and chitosan can improve fish fillet's quality, but the mechanism is not clear. Chitosan/gelatin coatings significantly prevented deterioration of golden pomfret fillet at 4 °C.
Feng, Xiao, Yang, Hongshun, Bansal, Nidhi   +2 more
core   +1 more source

Integrating Transcriptomic and Proteome Analysis to Understand Muscle Qualities and Related Regulatory Factors of Holstein Beef Under Transportation Stress

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
In Holstein steers subjected to 15 h of long‐distance transportation, beef exhibited marked differences in meat quality, myofibrillar structure, and flavor components compared with cattle slaughtered without prior transport. These differences included significantly increased shear force, water loss rate, and drip loss, shortened sarcomere length, and ...
Zhaomin Lei, Siyu Cheng, Ruixin Yang, Jinping Shi, Zemin Li, Wangjing Liu   +5 more
wiley   +1 more source

Proteolytic Activity of Zingiber officinale Extract: Interaction With Myofibrillar Proteins of Different Origins and Functional Effects in Meat Systems

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Ginger‐derived proteases were evaluated for their proteolytic activity toward isolated chicken and pork myofibrils and their effects during meat marination. The ginger extract showed a selective and moderate proteolytic activity, resulting in controlled protein degradation and improved meat quality, including tenderness, juiciness, flavor, and overall ...
Alessandro Crinò, Chiara Fabrizi, Andrea Menci, Katia Liburdi   +3 more
wiley   +1 more source