Results 101 to 110 of about 13,149 (237)

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo   +11 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda   +5 more
wiley   +1 more source

Embryonic exposure to 4-methylimidazole leads to zebrafish myofibril misalignment [PDF]

open access: yes, 2018
4‐methylimidazole (4‐MI) is an imidazole‐derived organic chemical compound that can be used as a raw material in the manufacture of diverse chemicals and has been identified as an ingredient of caramel color in soybean sauce, beers, and other soft drinks.
Tsai, Jen‐Ning;Sun, Chiao‐Yin;Ding, Yu‐Ju;Wang, Yun‐Hsin;Wen, Kang‐Chieh Lo Chi‐Chung;Lin, Jia‐Wei;Chang, Chiung‐Fang;Hsu, Li‐Sung;Chen, Hui‐Min;Fong, Tsorng‐Harn;Chen, Yau‐Hung   +12 more
core   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

open access: yes
Brain Pathology, EarlyView.
Michele Tosi   +6 more
wiley   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li   +19 more
wiley   +1 more source

Experiment K-6-10. Effects of zero gravity on myofibril protein content and isomyosin distribution in rodent skeletal muscle [PDF]

open access: yes, 1990
The purpose of this experiment was to investigate the effects of 12 days of zero gravity (0G) exposure (Cosmos 1887 Biosputnik) on the enzymatic properties, protein content, and isomyosin distribution of the myofibril fraction of the slow-twitch vastus ...
Herrick, R., Oganov, V., Baldwin, K.
core   +1 more source

Instrumentation to Study Myofibril Mechanics from Static to Artificial Simulations of Cardiac Cycle [PDF]

open access: yes, 2016
Many causes of heart muscle diseases and skeletal muscle diseases are inherited and caused by mutations in genes of sarcomere proteins which play either a structural or contractile role in the muscle cell.
Vikhorev, PG   +5 more
core   +1 more source

Sustained Release and Therapeutic Evaluation of Simvastatin‐Loaded Bioglass–Chitosan Gel Formulation for Skin Regeneration and Wound Healing Potential

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
A multifunctional chitosan–gallic acid hydrogel incorporated with heparin modified Zn–Ag doped bioglass and simvastatin was synthesized for chronic wound healing. The system shows antioxidant, antimicrobial, and pro‐angiogenic properties, promoting cell proliferation and collagen production.
Durgesh Kumar   +4 more
wiley   +1 more source

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi   +5 more
wiley   +1 more source

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