Results 81 to 90 of about 2,944 (198)

Correlative X‐ray imaging and fluorescence microscopy in hydrated environments

Journal of Synchrotron Radiation, EarlyView.
We present a combined imaging platform that integrates beamline‐compatible fluorescence microscopy with scanning small‐angle X‐ray scattering to enable sequential multimodal investigations of hydrated cells under near‐native conditions. We apply our method to ordered cytoskeletal structures in different cell types and demonstrate the direct correlation
Mangalika Sinha, Boram Yu, Rita Mendes Da Silva, Ulrike Rölleke, Peter Luley, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Manfred Burghammer, Sarah Köster   +8 more
wiley   +1 more source

Myofibril diameter is set by a finely tuned mechanism of protein oligomerization in Drosophila

eLife, 2019
Myofibrils are huge cytoskeletal assemblies embedded in the cytosol of muscle cells. They consist of arrays of sarcomeres, the smallest contractile unit of muscles.
Nicanor González-Morales, Yu Shu Xiao, Matthew Aaron Schilling, Océane Marescal, Kuo An Liao, Frieder Schöck   +5 more
doaj   +1 more source

Dual acellular subnormothermic machine perfusion for enhanced uterus preservation in a swine model

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In a porcine uterus transplantation model, subnormothermic machine perfusion reduced graft edema and better‐preserved post‐reperfusion contractility than static cold storage, highlighting its potential for uterus preservation, assessment, and future graft‐conditioning applications.
Lucile Cabanel, Haïzam Oubari, Bradley W. Ellis, Ludivine Dion, Vincent Lavoué, Carla Sousa, Loïc Van Dieren, Olivier Morel, Mark A. Randolph, Curtis L. Cetrulo Jr., Korkut Uygun, Alexandre G. Lellouch, Yanis Berkane, Basak E. Uygun   +13 more
wiley   +1 more source

Effect of Sarcoplasmic Protein Solutions Dried at Different Times and Rates on Water Migration in Lamb Myofibril In Vitro

Foods
To determine whether sarcoplasmic proteins affected water migration in myofibrils during air-drying, with protein denaturation as an indicator of sarcoplasmic protein changes, the extent of sarcoplasmic protein changes in lamb during air-drying was first
Weili Rao, Sijia Liu, Shiquan Kong, Zhenyu Wang, Zidan Shi, Jianming Cai   +5 more
doaj   +1 more source

Decreasing Mio levels results in abnormal myofibril ultrastructure.

, 2015
Transmission Electron Microscopy of Indirect Flight Muscles of adult Mef2-Gal4>MiodsRNA and Mef2-Gal4>Mio-IR females compared to Mef2-Gal4>GFP controls.
Grzegorz L. Polak (787000), Justin R. DiAngelo (351415), Anthony Pasqualino (787001), Stephen J. Beck (787003), James E. B. Docherty (787002)   +4 more
core   +1 more source

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang, Chunlan Deng, Xiaogang Guo, Hui Yan   +3 more
wiley   +1 more source

Identifying regulatory muscle processes in infantile and adult Pompe patients using a multi‐omic and morphological approach

Brain Pathology, EarlyView.
The study highlights differences in the regulatory processes of skeletal muscle, such as sarcomeric contractility, lysosomal and autophagic function, metabolic activity and immune regulation, at transcriptomic and proteomic levels in infantile and adult Pompe disease.
Alexander Schaiter, Keerthika Lohanadan, Alexander Mensch, Andreas Hentschel, Angela Rosenbohm, Cornelia Kornblum, Angela Roth, Tara Procida‐Kowalski, Heidrun H. Krämer, Andreas Hahn, Jörg Höhfeld, Dieter O. Fürst, Werner Stenzel, Peter F. M. van der Ven, Andreas Roos, Marek Bartkuhn, Anne Schänzer   +16 more
wiley   +1 more source

INTRINSIC BIREFRINGENCE OF GLYCERINATED MYOFIBRILS [PDF]

The Journal of Cell Biology, 1971
Patterns of intrinsic birefringence were revealed in formalin-fixed, glycerinated myofibrils from rabbit striated muscle, by perfusing them with solvents of refractive index near to that of protein, about 1.570. The patterns differ substantially from those obtained in physiological salt solutions, due to the elimination of edge- and form birefringence.
openaire   +2 more sources

Effects of creatine and taurine on myofibril sensitivity to calcium

, 2000
Effects of creatine and taurine on myofibril sensitivity to ...
Lebacq, Jean, Gailly, Philippe, Francaux, Marc, Cuisinier, C.   +3 more
core  

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source