Results 61 to 70 of about 2,944 (198)

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Quaking RNA-Binding Proteins Control Early Myofibril Formation by Modulating Tropomyosin

open access: yes, 2017
International audienceSkeletal muscle contraction is mediated by myofibrils, complex multi-molecular scaffolds structured into repeated units, the sarcomeres.
Ernest, Sylvain   +15 more
core   +1 more source

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

open access: yes, 2021
International audienceComplex animals build specialised muscles to match specific biomechanical and energetic needs. Hence, composition and architecture of sarcomeres and mitochondria are muscle type specific.
Luis, Nuno Miguel   +23 more
core   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

Peptic digestion of beef myofibrils is modified by prior marination

open access: yesFood & Nutrition Research, 2013
Background: Preparatory steps such as seasoning, marination, and cooking may induce changes in meat which affects the ability of the stomach to adequately digest it.
Nash Patel, Simon J. M. Welham
doaj   +1 more source

Effect of PH-Shifting Treatment on the Biochemical and Thermal Properties of Myofibril Protein

open access: yes, 2011
The pH-shifting treatment (including acid treatment and alkali treatment) caused partly denaturation and degrading of myofibril. The pH-shifting treatment increased the surface hydrophobicity, surface -SH content and total -SH content, reduced the Ca ...
Zhong Hai Li   +4 more
core   +1 more source

Theoretical considerations on myofibril stiffness

open access: yesBiophysical Journal, 1997
A discrete model of the interaction between individual myofilaments was developed to study the stiffness of a sarcomere for the case in which filament compliance is not negligible. Our model retains, in the limit, the characteristics of the previously published model by Ford et al. (Ford, L. E., A. F. Huxley, and R. M. Simmons. 1981.
Forcinito, M., Epstein, M., Herzog, W.
openaire   +2 more sources

Alterations in thin filament length during postnatal skeletal muscle development and aging in mice

open access: yesFrontiers in Physiology, 2014
The lengths of the sarcomeric thin filaments vary in a skeletal muscle-specific manner and help specify the physiological properties of skeletal muscle.
David S Gokhin   +4 more
doaj   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

The Regulation of Muscle Structure and Metabolism by Mio/dChREBP in Drosophila. [PDF]

open access: yesPLoS ONE, 2015
All cells require energy to perform their specialized functions. Muscle is particularly sensitive to the availability of nutrients due to the high-energy requirement for muscle contraction.
Grzegorz L Polak   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy