Results 41 to 50 of about 13,149 (237)

Architecture and molecular machinery of skeletal myofibers: a systematic review of the structure–function relationships

Frontiers in Cell and Developmental Biology
The skeletal muscle, one of the largest tissues in mammals, plays a crucial role in maintaining body movement and energy metabolism. Dysfunction or damage to the skeletal muscle can lead to various muscle diseases, such as muscular dystrophy, myasthenia,
Jing Zhao, Xu Du, Wei Fang, Hongxia Zhu, Binglin Yue   +4 more
doaj   +1 more source

Relationship between pre-rigor temperature of pork longissimus muscle, myofibril-bound calpain activity and protein degradation [PDF]

, 2023
The effect of pre-rigor temperature incubation on the activity and distribution in sarcoplasmic and myofibrillar fractions of calpains, and meat quality attributes was investigated. Porcine longissimus thoracis muscles were incubated pre-rigor at 14, 22,
Ertbjerg, Per, Puolanne, Eero, Lyu, Jian
core   +1 more source

Shrinkage Properties and Their Relationship with Degradation of Proteins Linking the Endomysium and Myofibril in Lamb Meat Submitted to Heating or Air Drying

Foods, 2022
The shrinkage of the connective tissue and myofiber of lamb meat submitted to heat treatment or air drying at different storage stages (1, 5 and 7 days) was evaluated herein. The longitudinal and transverse shrinkage of heated lamb meat was significantly
Weili Rao, Zhenxiao Shi, Sijia Liu, Ying Shu, Xiaoyu Chai, Zhisheng Zhang   +5 more
doaj   +1 more source

Myofibrils put the squeeze on nuclei [PDF]

Nature Cell Biology, 2017
During muscle development, nuclei travel from the centre of the myofibre to the periphery, a process defective in certain diseases. A new study reveals that this movement is due to centripetal forces imposed on nuclei by the crosslinking and contraction of myofibrils.
Jonathan N, Rosen, Mary K, Baylies
openaire   +2 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

Effect of PH-Shifting Treatment on the Biochemical and Thermal Properties of Myofibril Protein [PDF]

, 2011
The pH-shifting treatment (including acid treatment and alkali treatment) caused partly denaturation and degrading of myofibril. The pH-shifting treatment increased the surface hydrophobicity, surface -SH content and total -SH content, reduced the Ca ...
Zhong Hai Li, Qin Lu Lin, Jin Moon Kim, Xiang Jin Fu, Shi Ying Xu   +4 more
core   +1 more source

Video1_Cooperation between myofibril growth and costamere maturation in human cardiomyocytes.AVI [PDF]

, 2022
Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils ...
Huaiyu Shi (8795675), Bruce Z. Gao (9576083), James H. Henderson (8194806), Zhen Ma (281909), Chenyan Wang (8795678)   +4 more
core   +1 more source

High-intensity interval training alleviates exhaustive exercise-induced HSP70-assisted selective autophagy in skeletal muscle

Journal of Physiological Sciences, 2023
This study was designed to probe the effect of chaperone-assisted selective autophagy (CASA) on the maintenance of proteostasis during exhaustive exercise and uncover the alteration of CASA in muscle fibers with pre-high-intensity interval training (HIIT)
Jiao Lu, Liu-mei Zhang, Jing-jing Liu, Yu-ting Liu, Xiao-ye Lin, Xue-qi Wang, Yuan Zhang, Qiang Tang, Lin Liu   +8 more
doaj   +1 more source