Results 41 to 50 of about 13,101 (238)

Identifying the Structural Adaptations that Drive the Mechanical Load-Induced Growth of Skeletal Muscle: A Scoping Review

Cells, 2020
The maintenance of skeletal muscle mass plays a critical role in health and quality of life. One of the most potent regulators of skeletal muscle mass is mechanical loading, and numerous studies have led to a reasonably clear understanding of the ...
Kent W. Jorgenson, Stuart M. Phillips, Troy A. Hornberger   +2 more
doaj   +1 more source

Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament

FEBS Open Bio, 2022
Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura, Koichi Ojima, Susumu Muroya, Ken Kobayashi, Takanori Nishimura   +4 more
doaj   +1 more source

The ubiquitin ligase Ozz decreases the replacement rate of embryonic myosin in myofibrils

Physiological Reports, 2021
Myosin, the most abundant myofibrillar protein in skeletal muscle, functions as a motor protein in muscle contraction. Myosin polymerizes into the thick filaments in the sarcomere where approximately 50% of embryonic myosin (Myh3) are replaced within 3 h
Emi Ichimura, Koichi Ojima, Susumu Muroya, Takahiro Suzuki, Ken Kobayashi, Takanori Nishimura   +5 more
doaj   +1 more source

Cellular Aspects of Muscle Specialization Demonstrate Genotype – Phenotype Interaction Effects in Athletes

Frontiers in Physiology, 2019
IntroductionGene polymorphisms are associated with athletic phenotypes relying on maximal or continued power production and affect the specialization of skeletal muscle composition with endurance or strength training of untrained subjects.
Martin Flück, Manuel Kramer, Daniel P. Fitze, Stephanie Kasper, Martino V. Franchi, Paola Valdivieso   +5 more
doaj   +1 more source

Perturbation of cytosolic calcium by 2-aminoethoxydiphenyl borate and caffeine affects zebrafish myofibril alignment

, 2015
The objective of the current study was to investigate the effects of Ca2+ levels on myofibril alignment during zebrafish embryogenesis. To investigate how altered cytoplasmic Ca2+ levels affect myofibril alignment, we exposed zebrafish embryos to 2 ...
Yun‐Hsin Wang, I‐Jong Wang, Shen‐Liang Chen, Jen‐Cheng Wei, Hsin‐Ju Wu, Tsorng‐Harn Fong, Chen, Yau-hung, Wang, Yun-hsin, Juin‐Lin Horng, Xing‐Guang Chen, Hui‐Min Chen, Chi‐Chung Wen, Wei‐Yu Chen, Chao‐Yuan Chang, Yau‐Hung Chen   +14 more
core   +1 more source

Mio affects myofibril size.

, 2015
Scanning Electron Microscopy of Indirect Flight Muscles of adult Mef2-Gal4>MiodsRNA and Mef2-Gal4>Mio-IR females compared to Mef2-Gal4>GFP controls. Panels (A), (B) and (C) show cross sections of the myofibrils; bars indicate 0.5μm.
Grzegorz L. Polak (787000), Justin R. DiAngelo (351415), Anthony Pasqualino (787001), Stephen J. Beck (787003), James E. B. Docherty (787002)   +4 more
core   +1 more source

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

, 2021
International audienceComplex animals build specialised muscles to match specific biomechanical and energetic needs. Hence, composition and architecture of sarcomeres and mitochondria are muscle type specific.
Luis, Nuno Miguel, Rodier, Clement, Rival, Thomas, Avellaneda, Jerome, Brouilly, Nicolas, Schnorrer, Frank, Daian, Fabrice   +6 more
core   +1 more source

Architecture and molecular machinery of skeletal myofibers: a systematic review of the structure–function relationships

Frontiers in Cell and Developmental Biology
The skeletal muscle, one of the largest tissues in mammals, plays a crucial role in maintaining body movement and energy metabolism. Dysfunction or damage to the skeletal muscle can lead to various muscle diseases, such as muscular dystrophy, myasthenia,
Jing Zhao, Xu Du, Wei Fang, Hongxia Zhu, Binglin Yue   +4 more
doaj   +1 more source

The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila

, 2014
M.B. was funded by a Wellcome Trust Senior Investigator Award to P. Lawrence (WT096645MA).Muscle differentiation requires the assembly of high-order structures called myofibrils, composed of sarcomeres.
Estrada, B, Pérez-Moreno, J J, Martín-Bermudo, M D, Bischoff, M   +3 more
core   +1 more source

Shrinkage Properties and Their Relationship with Degradation of Proteins Linking the Endomysium and Myofibril in Lamb Meat Submitted to Heating or Air Drying

Foods, 2022
The shrinkage of the connective tissue and myofiber of lamb meat submitted to heat treatment or air drying at different storage stages (1, 5 and 7 days) was evaluated herein. The longitudinal and transverse shrinkage of heated lamb meat was significantly
Weili Rao, Zhenxiao Shi, Sijia Liu, Ying Shu, Xiaoyu Chai, Zhisheng Zhang   +5 more
doaj   +1 more source