Results 111 to 120 of about 15,563 (197)

Optimal neuromuscular performance requires motor neuron phosphagen kinases

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 2027-2059, 1 March 2026.
Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs   +10 more
wiley   +1 more source

Dynamic balance of myoplasmic energetics, redox state and protons in a fast‐twitch oxidative glycolytic skeletal muscle fibre

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 1840-1871, 1 March 2026.
Abstract figure legend We have developed a computational model of energy metabolism in fast‐twitch oxidative glycolytic muscle fibres. The model considers thermodynamically constrained enzyme kinetics derived from in vitro data and was validated against in vivo data from phosphorus magnetic resonance spectroscopy.
Jana Disch   +4 more
wiley   +1 more source

Oral amino acid tracer delivery detects feeding and exercise changes in myofibrillar protein synthesis rates in male adults

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Male participants were randomly assigned to consume [13C]leucine and [D5]phenylalanine tracers alone (FAST) or with a complete mixture of amino acids (0.25 g/kg) and carbohydrate (0.75 g/kg) at rest (FED) or after a bout of resistance exercise (EXFED). Plasma enrichment of both tracers increased rapidly after ingestion and remained elevated for up to 4–
Michael Mazzulla   +7 more
wiley   +1 more source

Lactate supplementation modulates molecular and functional responses during chronic neuromuscular electrical stimulation in male rats

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Abstract Lactate is increasingly recognized as a signaling molecule that modulates muscle plasticity. We examined the effects of oral L‐sodium lactate supplementation on skeletal muscle adaptation to chronic neuromuscular electrical stimulation (NMES) in rats.
Toshinori Yoshihara   +3 more
wiley   +1 more source

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