Results 31 to 40 of about 18,427 (259)
Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
, 2002 The effect of 3 different commercial starter cultures (Staphylococcus carnosus, Staphylococcus carnosits + Lactobocillus pentosus and Staphylococcus xylosus + Lactobacillus sakei on the myofibrillar proteins of pastirma was investigated.
Kaya, Mükerrem +2 more
core +1 more source
Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts
Advanced Functional Materials, EarlyView.Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett +15 more
wiley +1 more source
Degradation of myofibrillar proteins by cathepsins B and D [PDF]
Biochemical Journal, 1977 Cathepsin B and cathepsin D were purified from rat liver and skeletal muscle. Electrophoretic analyses revealed that the enzymes were highly purified, and isoelectric focusing demonstrated multiple forms of both enzymes. Purified actin and myosin, as well as actin and myosin in myofilaments and myofibrils, were degraded by the purified cathepsins B and
J W, Bird, W N, Schwartz, A M, Spanier
openaire +4 more sources
The Influence of Chopping Duration on the Degree of Proteins Extraction
Scientific Papers Animal Science and Biotechnologies, 2023 The quality of meat preparations, in terms of binding compositions, is directly influenced by the degree of extractibility of structural proteins, which in turn is influenced by a number of factors such as quality of raw and auxiliary materials, how ...
Daniela Ianițchi +5 more
doaj
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Foods, 2021 The objective of this study was to investigate the proteomic characteristics for the sarcoplasmic and myofibrillar proteomes of M. longissimus lumborum (LL) and M. psoasmajor (PM) from Small-tailed Han Sheep. During post-mortem storage periods (1, 3, and
Xiaoguang Gao +7 more
doaj +1 more source
AGING MEDICINE, EarlyView.Resistance training combined with ursolic acid supplementation restores anabolic signaling (PI3K/mTORC1) suppressed by diabetes, helping preserve muscle mass. This strategy may offer a potential therapeutic approach to combat muscle atrophy and support healthy aging in diabetic conditions.
Ashkan Sadeghi +4 more
wiley +1 more source
Oxidation of Myofibrillar Proteins in Human Heart Failure
Journal of the American College of Cardiology, 2011 We investigated the incidence and contribution of the oxidation/nitrosylation of tropomyosin and actin to the contractile impairment and cardiomyocyte injury occurring in human end-stage heart failure (HF) as compared with nonfailing donor hearts.Although there is growing evidence that augmented intracellular accumulation of reactive oxygen/nitrogen ...
CANTON, MARCELLA +5 more
openaire +3 more sources
Biotechnology and Bioengineering, EarlyView.ABSTRACT Cultivated meat production requires efficient differentiation of muscle progenitor cells into myotubes without relying on animal‐derived serum, which poses ethical and scalability challenges. This study aimed to develop a chemically defined, serum‐free medium optimized for bovine satellite cell differentiation.
Aysenaz Tavsanli +3 more
wiley +1 more source