Results 81 to 90 of about 1,546,271 (206)

Phosphoproteome analysis of sarcoplasmic and myofibrillar proteins in bovine longissimus muscle in response to postmortem electrical stimulation

, 2015
Protein phosphorylation changes of the sarcoplasmic and myofibrillar proteins in beef longissimus muscle in response to electrical stimulation (ES) was investigated. Sarcoplasmic and myofibrillar proteins purified from muscle samples taken at 0, 3 and 10
Sveriges lantbruksuniversitet., Lundström, Kerstin,, Karlsson, Anders,   +2 more
core   +1 more source

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

Sensitivity of myofibrillar proteins to glucocorticoid-induced muscle proteolysis

, 1987
Previous studies have reported that prolonged administration of pharmacological doses of glucocorticoids in young rats results in a rise in urinary 3-methyl-L-histidine (3-MH) excretion followed by a fall to initial levels by 8 days. To determine whether
M. N. Goodman, V. R. Young, A. G. Kayali
core   +1 more source

Desmin is not ubiquitously expressed in head and neck muscle fibers

Journal of Anatomy, EarlyView.
Desmin is not ubiquitously expressed in human head and neck muscle fibers. A subset of fibers showed absent or very weak desmin immunoreactivity, with corresponding reduction or absence of desmin mRNA expression. Abstract Desmin, a major muscle‐specific intermediate filament protein, is widely regarded as a ubiquitous component of mature skeletal ...
Per Stål, Jingxia Liu, Fatima Pedrosa Domellöf, Farhan Shah   +3 more
wiley   +1 more source

Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?

Experimental Physiology, EarlyView.
Abstract Understanding the turnover of proteins in tissues gives information as to how external stimuli result in phenotypic change. Nowhere is such phenotypic change more conspicuous than skeletal muscle, which can be effectively remodelled by increased loading, ageing and unloading (disuse), all of which are subject to modification by nutrition and ...
Changhyun Lim, James McKendry, Matthew Lees, Philip J. Atherton, Nicholas A. Burd, Andrew M. Holwerda, Luc J. C. van Loon, Chris McGlory, Cameron J. Mitchell, Kenneth Smith, Daniel J. Wilkinson, Tanner Stokes, Stuart M. Phillips   +12 more
wiley   +1 more source

An exploration of the methods to determine the protein‐specific synthesis and breakdown rates in vivo in humans

Physiological Reports, 2019
The present study explores the methods to determine human in vivo protein‐specific myofibrillar and collagenous connective tissue protein fractional synthesis and breakdown rates.
Lars Holm, Kasper Dideriksen, Rie H. Nielsen, Simon Doessing, Rasmus L. Bechshoeft, Grith Højfeldt, Marcus Moberg, Eva Blomstrand, Søren Reitelseder, Gerrit vanHall   +9 more
doaj   +1 more source

The effect of bed rest, unilateral limb immobilization and head‐down tilt on muscle protein synthesis: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Muscle disuse leads to muscle atrophy and a decrease in muscle function that is primarily driven by reduced muscle protein synthesis (MPS). The aim of this systematic review and meta‐analysis was to examine the effect of different models of muscle disuse on rates of MPS.
Konstantinos Prokopidis, Paul T. Morgan, Colleen S. Deane, Oliver C. Witard, David D. Church   +4 more
wiley   +1 more source

Applying lessons from limb muscle disuse and ageing to better understand ventilator‐induced diaphragm dysfunction

Experimental Physiology, EarlyView.
Abstract Mechanical ventilation (MV) is a life‐saving intervention applied to critically ill patients. A common consequence of MV is ventilator‐induced diaphragm dysfunction (VIDD), which is characterized by significant diaphragm atrophy and reduced contractile function. Older patients who receive MV are more likely to develop VIDD, have worse recovery,
P. H. C. Mesquita, J. L. Halle, J. D. Fuqua, B. F. Miller   +3 more
wiley   +1 more source

Influence of calpain on lamb myofibrillar proteins degradation during in vitro culture

Czech Journal of Food Sciences, 2018
Tenderness is an important indicator of meat quality, degradation plays important role during the maturation, therefore improving meat quality and tenderness.
Mukaddas MUHTAR, Ma Yi QIAO, Batur ABLIKIM, Arzugul ABDUWALI, Yusup SULAYMAN   +4 more
doaj   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source