Results 11 to 20 of about 53,888 (279)
Pitx2 in Embryonic and Adult Myogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2017 Skeletal muscle is a heterogeneous tissue that represents between 30 and 38% of the human body mass and has important functions in the organism, such as maintaining posture, locomotor impulse, or pulmonary ventilation.
Amelia E. Aranega +7 more
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Mitochondria as a Potential Regulator of Myogenesis [PDF]
The Scientific World Journal, 2013 Recent studies have shown that mitochondria play a role in the regulation of myogenesis. Indeed, the abundance, morphology, and functional properties of mitochondria become altered when the myoblasts differentiate into myotubes.
Akira Wagatsuma, Kunihiro Sakuma
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Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model
Frontiers in Cell and Developmental Biology, 2021 Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene.
Xiaopeng Shen +27 more
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iScience, 2022 Summary: Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified, knowledge of the global signaling networks and their downstream substrates during ...
Di Xiao +7 more
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Current Biology, 2016 The skeletal muscle system is the largest organ in motile animals, constituting between 35 and 55% of the human body mass, and up to 75% of the body mass in flying organisms like Drosophila. The flight muscles alone in flying insects comprise up to 65% of total body mass.
Ingo, Bothe, Mary K, Baylies
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006 Important functions in myogenesis have been proposed for FGF6, a member of the fibroblast growth factor family accumulating almost exclusively in the myogenic lineage. However, the analyses of Fgf6 (-/-) mutant mice gave contradictory results and the role of FGF6 during myogenesis remained largely unclear.
Christophe Chanoine +2 more
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RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin. [PDF]
Adv Sci (Weinh)Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Hossain MN +9 more
europepmc +2 more sources
Nutrition & Metabolism, 2021 Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or satellite cells, differentiate (by a process
Josiane Joseph, Jason D. Doles
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Wnt signaling in myogenesis [PDF]
Trends in Cell Biology, 2012 The formation of skeletal muscle is a tightly regulated process that is critically modulated by Wnt signaling. Myogenesis is dependent on the precise and dynamic integration of multiple Wnt signals allowing self-renewal and progression of muscle precursors in the myogenic lineage.
Natasha C. Chang +3 more
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Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. [PDF]
PLoS ONE, 2011 Understanding the dynamics of muscle transcriptome during development and between breeds differing in muscle growth is necessary to uncover the complex mechanism underlying muscle development.
Xiao Zhao +14 more
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