Results 11 to 20 of about 61,662 (273)

Coupling between Myogenesis and Angiogenesis during Skeletal Muscle Regeneration Is Stimulated by Restorative Macrophages

Stem Cell Reports, 2017
Summary: In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (
Claire Latroche, Michèle Weiss-Gayet, Laurent Muller, Cyril Gitiaux, Pascal Leblanc, Sophie Liot, Sabrina Ben-Larbi, Rana Abou-Khalil, Nicolas Verger, Paul Bardot, Mélanie Magnan, Fabrice Chrétien, Rémi Mounier, Stéphane Germain, Bénédicte Chazaud   +14 more
doaj   +2 more sources

Circular RNAs in myogenesis

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020
Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das, Aniruddha, Das, Debojyoti, Das, Kotb, Abdelmohsen, Amaresh C, Panda   +4 more
openaire   +4 more sources

The Role of Oxidative Stress in Skeletal Muscle Myogenesis and Muscle Disease

Antioxidants, 2022
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle cause it to continuously produce moderate levels of oxidant species, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS).
Di Lian, Ming-Ming Chen, Hanyu Wu, Shoulong Deng, Xiaoxiang Hu   +4 more
doaj   +2 more sources

Metabolic reprogramming promotes myogenesis during aging [PDF]

Frontiers in Physiology, 2019
Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Belli, R, Bonato, A, Caruso, M, Costelli, P, De Angelis, L, Ferraro, E., Leigheb, M, Mirabilii, S, Molfino, A, Muscaritoli, M, Ricciardi, Mr, Tafuri, A   +11 more
core   +4 more sources

Non-Coding RNA Regulates the Myogenesis of Skeletal Muscle Satellite Cells, Injury Repair and Diseases

Cells, 2019
Skeletal muscle myogenesis and injury-induced muscle regeneration contribute to muscle formation and maintenance. As myogenic stem cells, skeletal muscle satellite cells have the ability to proliferate, differentiate and self-renew, and are involved in ...
Yue Zhao, Mingming Chen, Di Lian, Yan Li, Yao Li, Jiahao Wang, Shoulong Deng, Kun Yu, Zhengxing Lian   +8 more
doaj   +2 more sources

Lnc-mg is a long non-coding RNA that promotes myogenesis

Nature Communications, 2017
Recent studies indicate important roles for long noncoding RNAs (lncRNAs) as essential regulators of myogenesis and adult skeletal muscle regeneration. However, the specific roles of lncRNAs in myogenic differentiation of adult skeletal muscle stem cells
Mu Zhu, Jiafan Liu, Jia Xiao, Li Yang, Mingxiang Cai, Hongyu Shen, Xiaojia Chen, Yi Ma, Sumin Hu, Zuolin Wang, An Hong, Yingxian Li, Yao Sun, Xiaogang Wang   +13 more
doaj   +2 more sources

Commitment to Myogenic Differentiation Significantly Aggravates the RNA Phenotype in Myotonic Dystrophy Type 1. [PDF]

Neuropathol Appl Neurobiol
DM1 myoblasts show mild defects, but RNA toxicity intensifies upon differentiation, where broad gene‐expression changes and escalating MBNL1‐driven splicing defects disrupt muscle‐specific pathways, underscoring a key vulnerability at the transition from myogenic precursor cells to myofibres in patients. ABSTRACT Aims Myotonic dystrophy type 1 (DM1) is
Ripken L, van den Broek WJAA, van Cruchten RTP, Smits JGA, Riepe TV, 't Hoen PAC, Wansink DG.   +6 more
europepmc   +2 more sources

circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop

Journal of Cachexia, Sarcopenia and Muscle, 2021
Circular RNAs (circRNAs) represent a novel class of non‐coding RNAs formed by a covalently closed loop and play crucial roles in many biological processes. Several circRNAs associated with myogenesis have been reported.
Junyu Yan, Yalan Yang, Xinhao Fan, G. Liang, Zishuai Wang, Jiju Li, Liyuan Wang, Yun Chen, A. A. Adetula, Yijie Tang, Kui Li, Da-Zhi Wang, Zhonglin Tang   +12 more
semanticscholar   +1 more source

Functional Non-coding RNA During Embryonic Myogenesis and Postnatal Muscle Development and Disease

Frontiers in Cell and Developmental Biology, 2021
Skeletal muscle is a highly heterogeneous tissue that plays a crucial role in mammalian metabolism and motion maintenance. Myogenesis is a complex biological process that includes embryonic and postnatal development, which is regulated by specific ...
Hongmei Luo, Wei Lv, Qian Tong, Jianjun Jin, Zaiyan Xu, B. Zuo   +5 more
semanticscholar   +1 more source

Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook

Nutrition & Metabolism, 2021
Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or satellite cells, differentiate (by a process
Josiane Joseph, Jason D. Doles
doaj   +1 more source