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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das +4 more
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MicroRNAs in skeletal myogenesis [PDF]
Cell Cycle, 2011 MicroRNAs (miRNAs) have emerged as critical regulators of numerous biological processes by modulating gene expression at the post-transcriptional level. It has become increasingly clear that almost all aspects of skeletal muscle development involve regulation by miRNAs.
Yejing, Ge, Jie, Chen
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Frontiers in Pharmacology, 2023 Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and ...
Miguel Marco-Bonilla +8 more
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HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes [PDF]
, 2018 Skeletal muscle exhibits a high regenerative capacity, mainly due to the ability of satellite cells to replicate and differentiate in response to appropriate stimuli. Epigenetic control is effective at different stages of this process.
Adamo, Sergio +9 more
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Molecular regulation of skeletal muscle tissue formation and development
Veterinární Medicína, 2018 This article provides a complex overview of the different stages of myogenesis with an emphasis on the molecular, genetic and cellular bases for skeletal muscle growth.
M. Nesvadbova, G. Borilova
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Hox Genes Regulate Muscle Founder Cell Pattern Autonomously and Regulate Morphogenesis Through Motor Neurons [PDF]
, 2010 The differentiation of myoblasts to form functional muscle fibers is a consequence of interactions between the mesoderm and ectoderm. The authors examine the role of segment identity in directing these interactions by studying the role of Hox genes in ...
Dutta, Devkanya +4 more
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The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis
Skeletal Muscle, 2011 Myogenesis is a complex and tightly regulated process, the end result of which is the formation of a multinucleated myofibre with contractile capability.
Knight James DR, Kothary Rashmi
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A novel in vitro model for the assessment of postnatal myonuclear accretion
Skeletal Muscle, 2018 Background Due to the post-mitotic nature of myonuclei, postnatal myogenesis is essential for skeletal muscle growth, repair, and regeneration. This process is facilitated by satellite cells through proliferation, differentiation, and subsequent fusion ...
Anita Kneppers +7 more
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Adaptive Myogenesis under Hypoxia [PDF]
Molecular and Cellular Biology, 2005 Previous studies have indicated that myoblasts can differentiate and repair muscle injury after an ischemic insult. However, it is unclear how hypoxia or glucose deprivation in the ischemic microenvironment affects myoblast differentiation. We have found that myogenesis can adapt to hypoxic conditions.
Zhong, Yun, Qun, Lin, Amato J, Giaccia
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myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis [PDF]
, 2014 Myogenesis involves the stable commitment of progenitor cells followed by the execution of myogenic differentiation, processes that are coordinated by myogenic regulatory factors, microRNAs and BAF chromatin remodeling complexes.
Bajard +52 more
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