Results 91 to 100 of about 64,746 (288)

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Advanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt, Joris Michaud, Ann Damgaard, Karoline Karlog, Eugenia Migliavacca, Sonia Karaz, Elham Pazirandeh‐Micol, Odd E. Johansen, Leonidas G. Karagounis, Bjørk W. Helge, William Hagemann, Michael Kjaer, Jerome N. Feige, Pascal Stuelsatz, Abigail L. Mackey   +14 more
wiley   +1 more source

Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. [PDF]

, 1996
Viral oncoproteins that inactivate the retinoblastoma tumor suppressor protein (pRb) family both block skeletal muscle differentiation and promote cell cycle progression.
Jacks, T, Lassar, AB, Mulligan, GJ, Novitch, BG   +3 more
core  

Herculin, a Fourth Member of the MyoD Family of Myogenic Regulatory Genes [PDF]

, 1990
We have identified and cloned herculin, a fourth mouse muscle regulatory gene. Comparison of its DNA and deduced amino acid sequences with those of the three known myogenic genes (MyoD, myogenin, and Myf-5) reveals scattered short spans with similarity ...
Miner, Jeffrey H., Wold, Barbara J.
core   +1 more source

The Enhanced Whey Protein Oral Bioavailability and Muscle Anabolism Ability by a Simple and Effective Piperine‐Whey Protein Synergistic Codelivery System

Advanced Science, EarlyView.
WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue, Kaiwen Wu, Bing Wei, Guiling Song, Congyu Sun, Xing Li, Xiangyu Liu, Zhaoxiang Ma, Mingchun Lv, Jasper Landman, Yuan Li   +10 more
wiley   +1 more source

Postmitotic Expression of SOD1G93A Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation

Mediators of Inflammation, 2015
To determine the role of mutant SOD1 gene (SOD1G93A) on muscle cell differentiation, we derived C2C12 muscle cell lines carrying a stably transfected SOD1G93A gene under the control of a myosin light chain (MLC) promoter-enhancer cassette.
Martina Martini, Gabriella Dobrowolny, Michela Aucello, Antonio Musarò   +3 more
doaj   +1 more source

Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration. [PDF]

, 2014
Here, we identify a role for the matrilin-2 (Matn2) extracellular matrix protein in controlling the early stages of myogenic differentiation. We observed Matn2 deposition around proliferating, differentiating and fusing myoblasts in culture and during ...
Deák, F., Dux, L., Juhász, H., Keller-Pintér, A., Kiricsi, M., Kiss, I., Korpos, E., Mendler, L., Mermod, N., Mátés, L., Ozsvári, B., Puskás, L.G., Sorokin, L., Szénási, T., Zvara, A.   +14 more
core   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Cry2 Is Critical for Circadian Regulation of Myogenic Differentiation by Bclaf1-Mediated mRNA Stabilization of Cyclin D1 and Tmem176b

Cell Reports, 2018
Summary: Circadian rhythms regulate cell proliferation and differentiation; however, little is known about their roles in myogenic differentiation. Our synchronized differentiation studies demonstrate that myoblast proliferation and subsequent myotube ...
Matthew Lowe, Jacob Lage, Ellen Paatela, Dane Munson, Reilly Hostager, Ce Yuan, Nobuko Katoku-Kikyo, Mercedes Ruiz-Estevez, Yoko Asakura, James Staats, Mulan Qahar, Michaela Lohman, Atsushi Asakura, Nobuaki Kikyo   +13 more
doaj   +1 more source

What determines growth potential and juvenile quality of farmed fish species? [PDF]

, 2013
Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
Alami-Durante, Alami-Durante, Albalat, Albors, Almuly, Almuly, Almuly, Andersen, Aragão, Ayala, Bai, Barresi, Baxendale, Betancor, Bizuayehu, Blaxter, Bodine, Booman, Bouraoui, Bouza, Bower, Bowman, Brent, Brix, Brodeur, Brooks, Buckingham, Bustin, Cade, Calduch-Giner, Calvo, Campinho, Campos, Campos, Campos, Canario, Canas, Carroll, Cerda, Cerda, Chatziplis, Chen, Chistiakov, Ciechanover, Cleveland, Cleveland, Codina, Cole, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Cruz-Garcia, De-Santis, Delbarre-Ladrat, Devoto, Dionísio, Dong, Douglas, Douglas, Dumont, Edvardsen, Engrola, Engrola, Erbay, Fauconneau, Fauconneau, Felip, Fernandes, Fernandes, Fernandes, Fernandes, Ferraresso, Ferraresso, Focant, Franklin, Galloway, Galloway, Galloway, Garcia De La Serrana, Gibson, Goetz, Goll, Gomez-Requeni, Gomez-Requeni, Gracey, Greer-Walker, Groves, Guyon, Hagen, Hagen, Hall, Hamre, Hayes, Hietakangas, Hinits, Hollway, Houlihan, Houlihan, Houlihan, Houlihan, Houlihan, Hubert, Hurling, Infante, Jackman, Jantzen, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Kamler, Kang, Kiørboe, Kloosterman, Koumans, Krasnov, Kuhl, Kuhl, Ladrat, Lakra, Lansard, Lecker, Liang, Link, Lopez, Lopez-Albors, Loukovitis, Louro, López-Albors, Maccatrozzo, Macqueen, Macqueen, Macqueen, Macqueen, Marschallinger, Martinez, Martinez, Martyniuk, Mascarello, Massault, Matsuoka, Merchie, Metzker, Mitter, Montserrat, Moore, Morais, Morais, Mork, Moutou, Nagasawa, Norton, Olsvik, Ostaszewska, Pajcini, Periago, Piñera, Portner, Powell, Pozios, Pérez-Sánchez, Quere, Reeds, Rehfeldt, Reid, Rescan, Rescan, Rescan, Rescan, Rowlerson, Rowlerson, Rowlerson, Roy, Roy, Saillant, Salem, Salem, Salem, Salvanes, Sanchez-Ramos, Sarropoulou, Seiliez, Seiliez, Seiliez, Shewring, Silva, Silva, Silva, Sonesson, Stears, Steinbacher, Stellabotte, Stellabotte, Stickland, Sveinsdottir, Sánchez-Ramos, Tan, Terova, Todorcevic, Valente, Valente, Valente, Veggetti, Veggetti, Vieira, Wang, Weatherley, Weil, Weinberg, West, Whitaker, Wienholds, Wienholds, Wiese, Wood, Wringe, Zane   +225 more
core   +3 more sources

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source