Results 91 to 100 of about 41,288 (271)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen   +5 more
wiley   +1 more source

The Effect of Pax3 Over-expression on Myoblast Function

open access: yes, 2009
The paired-box transcription factor 3 (Pax3), is a powerful myogenic regulatory factor during embryo-myogenesis. The expression of Pax3 is involved in determining somitic cell fate, resulting in the formation of the first differentiated muscle, the ...
Brijs, Erik
core  

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

open access: yesAnimal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar   +8 more
wiley   +1 more source

The characterisation and role of mighty during myogenesis

open access: yes, 2006
Myogenesis, or skeletal muscle formation, begins during embryogenesis and involves the proliferation of myoblasts followed by their exit from the cell-cycle to differentiate and form myotubes.
Davies, Todd John
core  

Nuclei of Non-Muscle Cells Bind Centrosome Proteins upon Fusion with Differentiating Myoblasts

open access: yes, 2009
Background: In differentiating myoblasts, the microtubule network is reorganized from a centrosome-bound, radial array into parallel fibres, aligned along the long axis of the cell.
Espigat-Georger Aude   +11 more
core   +1 more source

Effect of replicative senescence on myogenic differentiation of C2C12 cells.

open access: yes, 2023
Panel A shows representative images of C2C12 cells after culture with differentiation medium for 7 days. Myogenic differentiation was induced in cells subjected to passage once (passage 1), 10 times (passage 10), or 20 times (passage 20).
Hiroshi Ikegaya (4395847)   +2 more
core   +1 more source

ZBED6 Knockout Promotes Skeletal Muscle Development in Bama Pigs by Relieving Transcriptional Repression of CDKN1A

open access: yesAnimal Research and One Health, EarlyView.
Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma   +8 more
wiley   +1 more source

Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

open access: yesStem Cell Research & Therapy, 2020
Background Skeletal muscle is a complex and heterogeneous tissue accounting for approximately 40% of body weight. Excessive ectopic lipid accumulation in the muscle fascicle would undermine the integrity of skeletal muscle in humans but endow muscle with
Xin Zhang   +5 more
doaj   +1 more source

Schisandrae fructus enhances myogenic differentiation and inhibits atrophy through protein synthesis in human myotubes

open access: yes, 2016
Cy Hyun Kim,1,2,* Jin-Hong Shin,1,3,* Sung Jun Hwang,1,2 Yung Hyun Choi,4 Dae-Seong Kim,1,3 Cheol Min Kim2,51Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, 2Center for Anti ...
Hwang SJ   +5 more
core  

Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat production requires efficient differentiation of muscle progenitor cells into myotubes without relying on animal‐derived serum, which poses ethical and scalability challenges. This study aimed to develop a chemically defined, serum‐free medium optimized for bovine satellite cell differentiation.
Aysenaz Tavsanli   +3 more
wiley   +1 more source

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