Results 71 to 80 of about 814,354 (242)

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Nuclei of Non-Muscle Cells Bind Centrosome Proteins upon Fusion with Differentiating Myoblasts [PDF]

, 2009
Background: In differentiating myoblasts, the microtubule network is reorganized from a centrosome-bound, radial array into parallel fibres, aligned along the long axis of the cell.
Espigat-Georger Aude, Fant, Xavier, Xavier Fant, Aude Espigat-Georger, Merdes Andreas, Fant Xavier, Andreas Merdes, Srsen Vlastimil, Vlastimil Srsen, Srsen, Vlastimil, Espigat-Georger, Aude, Merdes, Andreas   +11 more
core   +2 more sources

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

TEAD4 Promotes Myogenic Differentiation of Porcine Skeletal Muscle Satellite Cells

Animals
Skeletal muscle satellite cells are indispensable for muscle growth and regeneration, and their myogenic differentiation is precisely controlled by transcription factors.
Huanhuan Zhou, Jiayi Zeng, Xiaoyu Zhang, Xinqi Zeng, Ke Xu, Hongbo Chen   +5 more
doaj   +1 more source

Effect of replicative senescence on myogenic marker expression during myogenic differentiation of C2C12 cells.

, 2023
Panel A shows representative Western blots of MyoD1, Myogenin, myosin heavy chain (MHC), and tubulin (as an internal control) in C2C12 cells after myogenic differentiation.
Hiroshi Ikegaya (4395847), Riko Tsurumi (14439452), Kaori Shintani-Ishida (14287748)   +2 more
core   +1 more source

Requirement of the transmembrane semaphorin Sema4C for myogenic differentiation [PDF]

FEBS Letters, 2005
Semaphorins constitute a large family of signaling proteins that contribute to axonal guidance. Here we demonstrate that the transmembrane semaphorin Sema4C is up‐regulated both in the early stage of differentiation of C2C12 mouse skeletal myoblasts into myotubes and during injury‐induced muscle regeneration in vivo.
Ko, Ji-Ae, Gondo, Toshikazu, Inagaki, Shinobu, Inui, Makoto   +3 more
openaire   +2 more sources

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

Advanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang, Fan Yang, Lu Wang, Zongtai Li, Weichang Li, Xinchun Zhang   +5 more
wiley   +1 more source

Slc2a6 regulates myoblast differentiation by targeting LDHB

Cell Communication and Signaling, 2022
Background Type 2 diabetes mellitus is a global health problem. It often leads to a decline in the differentiation capacity of myoblasts and progressive loss of muscle mass, which in turn results in deterioration of skeletal muscle function.
Xuan Jiang, Ninghan Feng, Yizhou Zhou, Xianlong Ye, Rong Wang, Jingwei Zhang, Siyuan Cui, Siyu Ji, Yongquan Chen, Shenglong Zhu   +9 more
doaj   +1 more source

Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation. [PDF]

, 2010
During myogenic differentiation the short mitochondria of myoblasts change into the extensively elongated network observed in myotubes. The functional relevance and the molecular mechanisms driving the formation of this mitochondrial network are unknown.
de Palma, Clara, Cipolat, S., Bassi, Maria Teresa, R. Allevi, C Panzeri, S Cipolat, Cossu, Giulio, Panzeri C, L. Scorrano, Pozzan, T., De Palma, C., S. Cipolat, T. Pozzan, Scorrano, L., M T Bassi, Cipolat, Sara, Pambianco S, Moncada, S., L Scorrano, Pisconti, A., Moncada S, G. Cossu, C. Panzeri, Cipolat S, Brunelli, S., Panzeri, Chris, Clementi E., G Cossu, Falcone S, Bassi MT, R Allevi, Clementi, Emilio, Pambianco, Sarah, C. De Palma, S Falcone, E Clementi, Allevi, Raffaele, Pisoni, Serena, Pisoni S, POZZAN, TULLIO, S. Pambianco, Falcone, S., S Moncada, Moncada, Salvador, Cossu G, S. Moncada, Pisconti, Addolorata, Brunelli, Silvia, S Brunelli, Pisoni, S., S Pambianco, Bassi, M. T., C De Palma, Allevi, R., S Pisoni, A Pisconti, Falcone, Sestina, T Pozzan, S. Pisoni, Brunelli S, Panzeri, C., Clementi, E., S. Brunelli, SCORRANO, LUCA, A. Pisconti, S. Falcone, M. T. Bassi, Allevi R, De Palma C, Pambianco, S., E. Clementi, Pisconti A, Cossu, G.   +72 more
core   +1 more source

The Homeodomain Protein Barx2 Promotes Myogenic Differentiation and Is Regulated by Myogenic Regulatory Factors [PDF]

Journal of Biological Chemistry, 2003
The homeobox protein Barx2 is expressed in both smooth and skeletal muscle and is up-regulated during differentiation of skeletal myotubes. Here we use antisense-oligonucleotide inhibition of Barx2 expression in limb bud cell culture to show that Barx2 is required for myotube formation.
Robyn, Meech, Helen, Makarenkova, David B, Edelman, Frederick S, Jones   +3 more
openaire   +2 more sources