Results 101 to 110 of about 41,288 (271)

A POTENTIAL ROLE OF MEF2C IN THE MYOGENIC PROGRESSION BESIDE TERMINAL DIFFERENTIATION

, 2012
MEF2C belongs to the family of Myocyte Enhancer Factor 2 transcription factors, which activate the muscle-specific gene expression program. Its activity is finely modulated at several levels but some aspects of this regulation still remains ...
MAGLI, Alessandro, BADODI, SARA, BARUFFALDI, Fiorenza, MOLINARI, Susanna, Margaret Buckingham, Didier Montarras, ANGELELLI, Cecilia, GANASSI, Massimo   +6 more
core  

JAK2/STAT2/STAT3 are required for myogenic differentiation

, 2008
Skeletal muscle satellite cell-derived myoblasts are mainly responsible for postnatal muscle growth and injury-induced regeneration. However, the cellular signaling pathways that control proliferation and differentiation of myoblasts remain poorly ...
Wang, Chihao, Wu, Zhenguo, Wang, Kepeng, Xiao, Fang, Wang, Haixia   +4 more
core   +1 more source

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

, 2017
Myoblast differentiation is indispensable for skeletal muscle formation and is governed by the precisely coordinated regulation of a series of transcription factors, including MyoD and myogenin, and transcriptional coregulators.
황은숙
core   +1 more source

Primary Pulmonary Mesenchymal Neoplasm With EWSR1::CREM Fusion: Cytologic Findings and Molecular Diagnosis

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay, Sanjay Mukhopadhyay, Swikrity U. Baskota   +2 more
wiley   +1 more source

Generation of skeletal muscle cells from pluripotent stem cells: advances and challenges

Frontiers in Cell and Developmental Biology, 2015
Human pluripotent stem cells (hPSCs) possess unlimited proliferative potential while maintaining the ability to differentiate into any cell type including skeletal muscle cells (SMCs). hPSCs are amenable to genetic editing and can be derived from patient
Ramzey eAbujarour, Bahram eValamehr
doaj   +1 more source

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

Developmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki, Anzu Taniguchi, Shunsuke Oka, Mizuki Mishima, Yuki Yamasaki, Yutaro Kawa, Saundra Schlesinger, Ryo Fujita, Chisa Shukunami, Hiroshi Asahara, Masafumi Inui   +10 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

High-density ZnO Nanowires as a Reversible Myogenic-Differentiation-Switch

, 2018
Mesoangioblasts are outstanding candidates for stem cell therapy and are already being explored in clinical trials. However, a crucial challenge in regenerative medicine is the limited availability of undifferentiated myogenic progenitor cells, since ...
Cesare Gargioli, Testa, Stefano, Falconi, C, Fuoco C., Fuoco, Claudia, Testa S., Fornetti, Ersilia, Giovanni Saggio, Desideri A., Rufini, Stefano, Saggio G., Arrabito G., Testa, S, Errico, Vito, Gargioli C., Fuoco, C, Errico V., Christian Falconi, Cannata, Stefano Maria, Falconi, Christian, Vito Errico, Stefano Cannata, Fornetti, E, Falconi C., Rufini S., Cannata S., Rufini, S, Errico, V, Cannata, S, Arrabito, G, Stefano Testa, Alessandro Desideri, Desideri, A, Stefano Rufini, Gargioli, Cesare, Gargioli, C, Saggio, Giovanni, Fornetti E., Arrabito, Giuseppe, Desideri, Alessandro, Ersilia Fornetti, Giuseppe Arrabito, Saggio, G, Claudia Fuoco   +43 more
core   +2 more sources

Bmi1 Is Expressed in Postnatal Myogenic Satellite Cells, Controls Their Maintenance and Plays an Essential Role in Repeated Muscle Regeneration

, 2011
PMCID: PMC3212532This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Robson, LG, Bird, K, Aleksandar Radunovic, Lesley G Robson, Di Foggia Valentina, Radunovic Aleksandar, Marino, S, Zhang, X, Xinyu Zhang, Katy Bird, Robson Lesley G., Marino Silvia, Bird Katy, Radunovic, A, Valentina Di Foggia, Zhang Xinyu, Lesley G. Robson, Di Foggia, V, Silvia Marino   +18 more
core   +1 more source