Results 1 to 10 of about 380,707 (403)

Non-muscle myosin II takes centre stage in cell adhesion and migration

open access: yesNature Reviews Molecular Cell Biology, 2009
Miguel Vicente-Manzanares   +1 more
exaly   +2 more sources

Multifaceted Function of Myosin-18, an Unconventional Class of the Myosin Superfamily

open access: yesFrontiers in Cell and Developmental Biology, 2021
Myosin is a diverse superfamily of motor proteins responsible for actin-based motility and contractility in eukaryotic cells. Myosin-18 family, including myosin-18A and myosin-18B, belongs to an unconventional class of myosin, which lacks ATPase motor ...
Zhaohui Ouyang   +12 more
doaj   +1 more source

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

open access: yeseLife, 2021
Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that ...
Eric T Hall   +12 more
doaj   +1 more source

Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. [PDF]

open access: yesPLoS ONE, 2010
Non-muscle cells express multiple myosin-II motor proteins myosin IIA, myosin IIB and myosin IIC transcribed from different loci in the human genome. Due to a significant homology in their sequences, these ubiquitously expressed myosin II motor proteins ...
Venkaiah Betapudi
doaj   +1 more source

Motor-driven advection competes with crowding to drive spatiotemporally heterogeneous transport in cytoskeleton composites

open access: yesFrontiers in Physics, 2022
The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion to ...
Janet Y. Sheung   +6 more
doaj   +1 more source

Multiplying myosins [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Myosins are a diverse family of actin-based molecular motors that appeared early in eukaryotic evolution. Just how early, and how diverse, has begun to become clear from work that appears in this issue of PNAS (1) and recent work from Nature (2). For most of its existence, the term “myosin” applied only to the actin-activated ATPase that forms the ...
Holly V, Goodson, Scott C, Dawson
openaire   +2 more sources

Contiguity and Structural Impacts of a Non-Myosin Protein within the Thick Filament Myosin Layers

open access: yesBiology, 2021
Myosin dimers arranged in layers and interspersed with non-myosin densities have been described by cryo-EM 3D reconstruction of the thick filament in Lethocerus at 5.5 Å resolution.
Lynda M. Menard   +2 more
doaj   +1 more source

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

open access: yesCirculation, 2020
Supplemental Digital Content is available in the text. Background: Hypertrophic cardiomyopathy (HCM) is caused by pathogenic variants in sarcomere protein genes that evoke hypercontractility, poor relaxation, and increased energy consumption by the heart
Christopher N Toepfer   +27 more
semanticscholar   +1 more source

The spreading of myosin [PDF]

open access: yesBiochemical Journal, 1935
Whereas most proteins so far studied show spreading at their isoelectric points or on strongly acid solutions (we have examined more or less thoroughly ovalbumin, zein, gliadin, insulin, pepsin, trypsin, ovoglobulin, ovomucoid, caseinogen, globin and haemoglobin) some proteins do not spread, when tested by our usual technique. Gelatin is a bad spreader
E, Gorter, H, Van Ormondt
openaire   +2 more sources

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