Results 1 to 10 of about 281,418 (301)
The order of things: phosphate release or the power stroke, which does actomyosin do first? [PDF]
Frontiers in PhysiologyMyosins are a highly conserved super family of motor proteins that are responsible for driving a host of intracellular processes in eukaryotes, from muscle contraction to vesicular transport.
Edward P. Debold +2 more
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eLife, 2021 Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that ...
Eric T Hall +12 more
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Frontiers in Physics, 2022 The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion to ...
Janet Y. Sheung +6 more
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Myosin II motor proteins with different functions determine the fate of lamellipodia extension during cell spreading. [PDF]
PLoS ONE, 2010 Non-muscle cells express multiple myosin-II motor proteins myosin IIA, myosin IIB and myosin IIC transcribed from different loci in the human genome. Due to a significant homology in their sequences, these ubiquitously expressed myosin II motor proteins ...
Venkaiah Betapudi
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Myosin II filament dynamics in actin networks revealed with interferometric scattering microscopy [PDF]
, 2020 The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the remodeling acto-myosin network modifies local membrane organization, but the molecular details are ...
Fineberg, A. +7 more
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Proceedings of the National Academy of Sciences, 2006 Myosins are a diverse family of actin-based molecular motors that appeared early in eukaryotic evolution. Just how early, and how diverse, has begun to become clear from work that appears in this issue of PNAS (1) and recent work from Nature (2). For most of its existence, the term “myosin” applied only to the actin-activated ATPase that forms the ...
Holly V, Goodson, Scott C, Dawson
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Contiguity and Structural Impacts of a Non-Myosin Protein within the Thick Filament Myosin Layers
Biology, 2021 Myosin dimers arranged in layers and interspersed with non-myosin densities have been described by cryo-EM 3D reconstruction of the thick filament in Lethocerus at 5.5 Å resolution.
Lynda M. Menard +2 more
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Stratification relieves constraints from steric hindrance in the generation of compact acto-myosin asters at the membrane cortex [PDF]
, 2020 Recent in-vivo studies have revealed that several membrane proteins are driven to form nanoclusters by active contractile flows arising from F-actin and myosin at the cortex. The mechanism of clustering was shown to be arising from the dynamic patterning
Bhat, Abrar +5 more
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Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure
Biology, 2021 Structural changes in the myosin II light meromyosin (LMM) that influence thick filament mechanical properties and muscle function are modulated by LMM-binding proteins.
Lynda M. Menard +2 more
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Biomolecules, 2020 Cardiovascular diseases are one of the leading causes of death in developing countries, generally originating as coronary artery disease (CAD) or hypertension. In later stages, many CAD patients develop left ventricle dysfunction (LVD).
Surendra Kumar +2 more
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