Results 21 to 30 of about 161,523 (294)
Meat quality and its association with muscle fibers
This review makes an in-depth and updated exploration of the type of muscle fiber and its association with the quality characteristics of beef in bovines.
Cruz Elena Enriquez Valencia+2 more
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Nonmusclemyosin 2 (NM-2) powers cell motility and tissue morphogenesis by assembling into bipolar filaments that interact with actin. Although the enzymatic properties of purified NM-2 motor fragments have been determined, the emergent properties of ...
Luca Melli+7 more
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While the dynamin GTPase Drp1 plays a critical role during mitochondrial fission, mechanisms controlling its recruitment to fission sites are unclear. A current assumption is that cytosolic Drp1 is recruited directly to fission sites immediately prior to
Wei-ke Ji+4 more
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Mucormycosis is an emerging lethal invasive fungal infection. The infection caused by fungi belonging to the order Mucorales has been reported recently as one of the most common fungal infections among COVID-19 patients.
Trung Anh Trieu+4 more
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The precise assembly of inner ear hair cell stereocilia into rows of increasing height is critical for mechanotransduction and the sense of hearing. Yet, how the lengths of actin-based stereocilia are regulated remains poorly understood. Mutations of the
Qing Fang+9 more
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von Willebrand factor binding to myosin assists in coagulation
: von Willebrand factor (VWF) binds to platelets and collagen as a means of facilitating coagulation at sites of injury. Recent evidence has shown that myosin can serve as a surface for thrombin generation and binds to activated factor V and factor X. We
Veronica H. Flood+7 more
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Myosin II isoforms play distinct roles in adherens junction biogenesis
Adherens junction (AJ) assembly under force is essential for many biological processes like epithelial monolayer bending, collective cell migration, cell extrusion and wound healing. The acto-myosin cytoskeleton acts as a major force-generator during the
Mélina L Heuzé+9 more
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Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics
The mass spectrometric analysis of skeletal muscle proteins has used both peptide-centric and protein-focused approaches. The term ‘top-down proteomics’ is often used in relation to studying purified proteoforms and their post-translational ...
Paul Dowling+3 more
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Nuclear filaments: role in chromosomal positioning and gene expression
Nuclear lamins form an elastic meshwork underlying the inner nuclear membrane and provide mechanical rigidity to the nucleus and maintain shape. Lamins also maintain chromosome positioning and play important roles in several nuclear processes like ...
Manindra Bera, Kaushik Sengupta
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The design of compounds that can discriminate between closely related target proteins remains a central challenge in drug discovery. Specific therapeutics targeting the highly conserved myosin motor family are urgently needed as mutations in at least six
Artur Meller+9 more
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