Results 21 to 30 of about 380,707 (403)
Current Opinion in Structural Biology, 2014 The folding and assembly of myosin motor proteins is essential for most movement processes at the cellular, but also at the organism level. Importantly, myosins, which represent a very diverse family of proteins, require the activity of general and specialized folding factors to develop their full motor function.
Hellerschmied, Doris, Clausen, Tim
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The coagulation of myosin in muscle [PDF]
, 1937 The coagulation of myosin is one of the few changes in the proteins of muscle known to take place during contraction and rigor. Although under certain conditions as much as one-third of the total protein of muscle may become insoluble, the significance ...
Mirsky, A. E.
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Myosin XVI in the Nervous System
Cells, 2020 The myosin family is a large inventory of actin-associated motor proteins that participate in a diverse array of cellular functions. Several myosin classes are expressed in neural cells and play important roles in neural functioning.
Elek Telek +2 more
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Science Advances, 2020 Hypertrophic cardiomyopathy–causing mutations disrupt a key regulatory off state of myosin in thick filaments. Hypertrophic cardiomyopathy (HCM) mutations in β-cardiac myosin and myosin binding protein-C (MyBP-C) lead to hypercontractility of the heart ...
Saswata S. Sarkar +6 more
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eLife, 2015 Myosin 5a is a dual-headed molecular motor that transports cargo along actin filaments. By following the motion of individual heads with interferometric scattering microscopy at nm spatial and ms temporal precision we found that the detached head ...
Joanna Andrecka +8 more
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Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)*
Journal of Biological Chemistry, 1996 The small GTPase Rho is implicated in physiological functions associated with actin-myosin filaments such as cytokinesis, cell motility, and smooth muscle contraction.
M. Amano +7 more
semanticscholar +1 more source
The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer [PDF]
, 2014 The contractile actin-myosin cytoskeleton provides much of the force required for numerous cellular activities such as motility, adhesion, cytokinesis and changes in morphology.
AP Somlyo +62 more
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Frontiers in Physiology, 2020 While high-load resistance training increases muscle hypertrophy, the intramuscular protein responses to this form of training remains largely unknown. In the current study, recreationally resistance-trained college-aged males (N = 15; mean ± SD: 23 ± 3 ...
Christopher G. Vann +18 more
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Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties [PDF]
, 2017 In search of myosin II inhibitors with superior research tool properties, a chemical optimization campaign of the blebbistatin scaffold was conducted in this paper. (S)-Blebbistatin is the best known small-molecule inhibitor of myosin II ATPase activity.
Bracke, Marc +6 more
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Mechanisms in the pathogenesis of poststroke spasticity
Неврология, нейропсихиатрия, психосоматика, 2011 Objective: to study the mechanisms of poststroke spasticity and the role of structural and functional impairments of skeletal muscles in its pathogenesis. Patients and methods.
E. A. Katushkina +3 more
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