Results 21 to 30 of about 159,767 (320)

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

open access: yeseLife, 2021
Morphogens function in concentration-dependent manners to instruct cell fate during tissue patterning. The cytoneme morphogen transport model posits that specialized filopodia extend between morphogen-sending and responding cells to ensure that ...
Eric T Hall   +12 more
doaj   +1 more source

Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration

open access: yeseLife, 2020
Collective cell migration is central to many developmental and pathological processes. However, the mechanisms that keep cell collectives together and coordinate movement of multiple cells are poorly understood. Using the Drosophila border cell migration
Yujun Chen   +9 more
doaj   +1 more source

Motor-driven advection competes with crowding to drive spatiotemporally heterogeneous transport in cytoskeleton composites

open access: yesFrontiers in Physics, 2022
The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion to ...
Janet Y. Sheung   +6 more
doaj   +1 more source

Characterization and analysis of myosin gene family in the whitefly (Bemisia tabaci)

open access: yesAIMS Molecular Science, 2022
Myosin is an actin-based motor protein that widely exists in muscle tissue and non-muscle tissue, and myosin of a diverse subfamily has obvious differences in structure and cell function.
Kui Wang   +7 more
doaj   +1 more source

Model for processive movement of myosin V and myosin VI [PDF]

open access: yesChinese Physics, Vol.14, No.4 (2005) 744-752, 2003
Myosin V and myosin VI are two classes of two-headed molecular motors of the myosin superfamily that move processively along helical actin filaments in opposite directions. Here we present a hand-over-hand model for their processive movements. In the model, the moving direction of a dimeric molecular motor is automatically determined by the relative ...
arxiv   +1 more source

Distinct roles of two myosins in C. elegans spermatid differentiation.

open access: yesPLoS Biology, 2019
During spermatogenesis, interconnected haploid spermatids segregate undesired cellular contents into residual bodies (RBs) before detaching from RBs. It is unclear how this differentiation process is controlled to produce individual spermatids or motile ...
Junyan Hu   +7 more
doaj   +1 more source

Actin reorganization throughout the cell cycle mediated by motor proteins [PDF]

open access: yes, 2021
Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over the course of the cell cycle, when cortical actin transitions between open patched meshworks, homogeneous distributions, and aligned bundles.
arxiv   +1 more source

HLH-1 Modulates Muscle Proteostasis During Caenorhabditis elegans Larval Development

open access: yesFrontiers in Cell and Developmental Biology, 2022
Muscle proteostasis is shaped by the myogenic transcription factor MyoD which regulates the expression of chaperones during muscle differentiation. Whether MyoD can also modulate chaperone expression in terminally differentiated muscle cells remains open.
Khairun Nisaa, Anat Ben-Zvi
doaj   +1 more source

Stochastic dynamics and mechanosensitivity of myosin II minifilaments [PDF]

open access: yesPhilipp J Albert et al 2014 New J. Phys. 16 093019, 2014
Tissue cells are in a state of permanent mechanical tension that is maintained mainly by myosin II minifilaments, which are bipolar assemblies of tens of myosin II molecular motors contracting actin networks and bundles. Here we introduce a stochastic model for myosin II minifilaments as two small myosin II motor ensembles engaging in a stochastic tug ...
arxiv   +1 more source

Sensitivity of small myosin II ensembles from different isoforms to mechanical load and ATP concentration [PDF]

open access: yesPhys. Rev. E 94, 052403 (2016), 2016
Based on a detailed crossbridge model for individual myosin II motors, we systematically study the influence of mechanical load and adenosine triphosphate (ATP) concentration on small myosin II ensembles made from different isoforms. For skeletal and smooth muscle myosin II, which are often used in actomyosin gels that reconstitute cell contractility ...
arxiv   +1 more source

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