Results 61 to 70 of about 161,523 (294)

Differential activation of AKT isoforms by growth factors in human myotubes

open access: yesPhysiological Reports, 2023
AKT signaling plays a crucial role in muscle physiology, and is activated by stimuli, including insulin, growth factors, and exercise. Three AKT isoforms have been identified in mammals, and they possess both distinct and redundant functions. However, it
Brandon M. Roberts   +2 more
doaj   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

open access: yesAdvanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue   +3 more
wiley   +1 more source

Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton

open access: yesViruses, 2018
Viruses have a dual nature: particles are “passive substances” lacking chemical energy transformation, whereas infected cells are “active substances” turning-over energy.
I-Hsuan Wang   +3 more
doaj   +1 more source

Myosin Mechanochemistry [PDF]

open access: yesStructure, 2007
With several dozen high-resolution structures of various myosin motor domains available, there remains a problem of identifying their relevance to intermediates in the ATPase cycle. In this issue of Structure, Yang et al. (2007) add to the discussion in the light of new molluscan myosin structures.
openaire   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

open access: yesAdvanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu   +7 more
wiley   +1 more source

Entosis Is Induced by Glucose Starvation

open access: yesCell Reports, 2017
Entosis is a mechanism of cell death that involves neighbor cell ingestion. This process occurs in cancers and promotes a form of cell competition, where winner cells engulf and kill losers.
Jens C. Hamann   +6 more
doaj   +1 more source

Skeletal muscle single fiber force production declines early in juvenile male mice with chronic kidney disease

open access: yesPhysiological Reports, 2023
Children with chronic kidney disease (CKD) frequently exhibit delayed physical development and reduced physical performance, presumably due to skeletal muscle dysfunction.
Brent A. Momb   +3 more
doaj   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John   +5 more
wiley   +1 more source

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

open access: yesAdvanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer   +8 more
wiley   +1 more source

Gamma-radiation induced agglomeration of chicken muscle myosin and actin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2004
Radiolytic behaviour of the major vertebrate muscle proteins: fibrillar myosin (molar mass, Mm = 520,000 g/mol) and filament forming actin (Mm = 42,050 g/mol) was studied using a SDS-polyacrylamide gel electrophoresis and quantified by high precision ...
BRATOLJUB H. MILOSAVLJEVIC   +2 more
doaj  

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