Frontiers in Neuroscience, 2018 N,N-dimethyltryptamine (DMT) is a powerful serotonergic psychedelic whose exogenous administration elicits striking psychedelic effects in humans. Studies have identified DMT and analogous compounds (e.g., 5-hydroxy-DMT, 5-methoxy-DMT) alongside of an ...
Jon G. Dean
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Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]
, 2018 Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V +15 more
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The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells [PDF]
, 2016 N,N-dimethyltryptamine (DMT) is a potent endogenous hallucinogen present in the brain of humans and other mammals. Despite extensive research, its physiological role remains largely unknown.
Djurovic, Srdjan +5 more
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Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
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A Review of Aeruginascin and Potential Entourage Effect in Hallucinogenic Mushrooms
European Psychiatry, 2022 Introduction The 5-HT2A agonist classic psychedelic, psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a tryptophan, indole-based alkaloid present in up to 2% of certain hallucinogenic “magic” mushroom species; typically Psilocybe azurescens,
P. Chue +4 more
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The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization [PDF]
, 2016 Ayahuasca is an Amazonian psychoactive brew of two main components. Its active agents are β-carboline and tryptamine derivatives. As a sacrament, ayahuasca is still a central element of many healing ceremonies in the Amazon Basin and its ritual ...
Bokor, Petra +2 more
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A mood disorder episode with an onset under chronic cannabis consumption and accompanied with psychotic features immediately after N, N-Dimethyltryptamine (DMT) use: a case report [PDF]
Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011 , N-dimethyltryptamine (DMT) is a serotonin agonist hallucinogen, similar to lysergic acid diethylamide (LSD). Syntetic production of DMT as well as extraction from several plants of South American flora is possible.
Güliz Özgen +3 more
doaj
Potential therapeutic use of ayahuasca: A literature review [PDF]
Acta AmazonicaAyahuasca is a psychoactive decoction originally used in indigenous Amazonian culture. It consists of a dense brown liquid that most frequently results from the decoction of two plants native to the Amazon rainforest, Psychotria viridis (Rubiaceae) and ...
Salvana Priscylla Manso COSTA +9 more
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Proposal of 5-methoxy-N-methyl-N-isopropyltryptamine consumption biomarkers through identification of in vivo metabolites from mice [PDF]
, 2017 New psychoactive substances (NPS) are a new breed of synthetically produced substances designed to mimic the effects of traditional illegal drugs. Synthetic cannabinoids and synthetic cathinones are the two most common groups, which try to mimic the ...
Barneo-Muñoz, Manuela +5 more
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Novel Psychoactive Substances: : the pharmacology of stimulants and hallucinogens [PDF]
, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis in Expert Review of Clinical Pharmacology, on March 2016, available online at doi: : http://www.tandfonline.com/doi/full/10.1586/17512433.2016.1167597.There are increasing levels ...
Corkery JM +11 more
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