Results 51 to 60 of about 13,568,693 (193)
Psychedelics and immunomodulation: Novel approaches and therapeutic opportunities
Frontiers in Immunology, 2015 Classical psychedelics are psychoactive substances, which, besides their psychopharmacological activity, have also been shown to exert significant modulatory effects on immune responses by altering signaling pathways involved in inflammation, cellular ...
Attila eSzabo
doaj +1 more source
N,N-dimethyltryptamine and Amazonian ayahuasca plant medicine [PDF]
, 2022 Objective Reports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post-traumatic stress disorder, anxiety and specific psychoneuroendocrine immune system pathologies.
Robertshaw, Thomas L. +8 more
core +1 more source
Addiction, EarlyView.Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden +10 more
wiley +1 more source
Who smokes dimethyltryptamine (DMT)? Characteristics of recreational DMT use
, 2023 This project is a examination of characteristics of individuals who smoke recreational dimethyltryptamine (DMT)
Mitchell Earleywine, Jamie Parnes
core +1 more source
Frontiers in Psychiatry, 2021 While psychedelics may have therapeutic potential for treating mental health disorders such as depression, further research is needed to better understand their biological effects and mechanisms of action when considering the development of future novel ...
Sylvana Vilca-Melendez +3 more
doaj +1 more source
Addiction, EarlyView.Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve +6 more
wiley +1 more source
Para-psychology, N, N-dimethyltryptamine and the pineal gland [PDF]
, 2018 In the last decades, one of the psychedelic substances which has gained high attention for its implications in several para-psychological phenomena (including out-of-body states, deep changes in sensory perception, mood, and thought, travels in ...
Firenzuoli F. +9 more
core
Frontiers in PsychiatryIntroductionPsychedelic agents have regained the attention of pharmaceutical companies as promising treatments for depressive episodes. 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), an atypical psychedelic, is emerging as a potentially effective, novel ...
Aleksander Kwaśny +2 more
doaj +1 more source
Safety pharmacology of acute mescaline administration in healthy participants
British Journal of Clinical Pharmacology, EarlyView.Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber +4 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 10, Page 1244-1255, October 2026.First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman +8 more
wiley +1 more source