Results 121 to 130 of about 10,590,172 (275)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

“Detrás de las noticias”. Notas sobre una experiencia de relevamiento de fuentes periodísticas. Algunas consideraciones sobre la prensa local villense

Historia Regional, 2016
El presente trabajo surge en el marco de la cátedra Metodología de la Investigación dictada en la carrera Historia del Instituto Superior del Profesorado N° 3 de la ciudad de Villa Constitución, en la cual se decide realizar un relevamiento de las ...
Castro, Fabiana, Juncos, Mariángeles, Saucedo, Cintia, Sosa, Antonela   +3 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Crèdits i informació

Revista d'Innovació Docent Universitària, 2011
Crèdits i informació de la Revista d'Innovació Docent ...
RIDU n. 3
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A propósito del asesinato de Fuentealba: El discurso de poder en Sobish

Historia Regional, 2008
Desde el Análisis Crítico del Discurso, el presente trabajo analiza la solicitada que Jorge Omar Sobisch, Gobernador de la Provincia del Neuquén publicó en los periódicos nacionales el 13 de abril de 2007, luego de la muerte del Maestro Carlos Fuentealba
Delia Cejas, Cristina Di Bernardo, Alejandra Garrini, Liliana Pérez   +3 more
doaj  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Formas de subsistencia en barrio Luján de Villa Constitución

Historia Regional, 2004
Nuestro trabajo consistió en primera instancia en observar las condiciones sociales en las que vivían y viven los habitantes de Barrio Luján. Si bien este barrio está denominado con este rótulo, tiene todas las características de una villa, en cuanto a ...
Nadia Alejandra Abrigo, María Guadalupe Mercuri, Ramona Angélica Monzón, Juan Pablo Tentor   +3 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source