Results 101 to 110 of about 14,619 (195)
1H MRS, in combination with quantification methods using model functions based on prior knowledge of chemical shifts and coupling constants, allows the determination of characteristic metabolic processes in healthy and diseased tissue. Using the functional relationships δpHT$$ \delta \left( pH,T\right) $$ and JpHT$$ J\left( pH,T\right) $$ enables this ...
Felizitas C. Wermter +2 more
wiley +1 more source
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila +10 more
wiley +1 more source
A Novel Homozygous Variant in the Aspartoacylase Gene Causes Canavan Disease-Case Report
Glu178 is the active site residue essential for substrate affinity and catalytic activity of the aspartoacylase enzyme. Sanger sequencing in an infant with Canavan disease revealed a homozygous ASPA: c.532G>A: p. (Glu178Lys) variant.
Archana Vaddinahalli Kariyappa +7 more
doaj +1 more source
Lithium from mood stabilizer to putative cognitive enhancer [PDF]
This study is the first to have demonstrated, by means of a highly sensitive test of visual memory, a potential hippocampus neuroprotective effect of lithium in patients with BD. Undoubtedly, other studies are needed to finally recognize lithium as a
Bersani, Giuseppe +2 more
core +2 more sources
Catatonia an Unexpected Side Effect of Electroconvulsive Therapy: A Case Report
This case report highlights an unexpected development of catatonia following electroconvulsive therapy in a patient with schizoaffective disorder. The catatonia resolved promptly after discontinuing psychotropic interventions, emphasizing the need for careful monitoring during ECT, especially in patients with complex psychiatric histories.
Fatemeh sheikhmoonesi +3 more
wiley +1 more source
Tine Maria Hansen,1 Anne Estrup Olesen,2 Carsten Wiberg Simonsen,1 Asbjørn Mohr Drewes,2,3 Jens Brøndum Frøkjær11Mech-Sense, Department of Radiology, 2Mech-Sense, Department of Gastroenterology, 3Center for Sensory-Motor ...
Hansen TM +4 more
doaj
Abstract Objective This systematic review synthesizes evidence on multimodal machine learning (ML) decision support systems for epilepsy surgery focusing on postsurgical outcome prediction, with emphasis on methodological quality and implications for clinical practice.
Mattia Mercier +2 more
wiley +1 more source
Metabolic changes in concussed American football players during the acute and chronic post-injury phases [PDF]
Background Despite negative neuroimaging findings many athletes display neurophysiological alterations and post-concussion symptoms that may be attributable to neurometabolic alterations.
Luke C Henry +6 more
core +2 more sources
N-acetylaspartate: Genomics, phenomics and metabonomics
N-acetylaspartate (NAA) is the second most abundant metabolite in the brain. Its physiological roles have eluded researchers for sixty years and hypotheses on its functions are contentious. Clinical evidence suggests both absence and accumulation of NAA are poorly tolerated. Hypoacetylaspartia is caused by a null-mutation of the NAA-synthesizing enzyme
openaire +2 more sources
Chorioamnionitis and Early Brain Development
The association of chorioamnionitis and early postnatal risk factors for white matter injury (WMI) and its effect on early brain development were determined in a study at University of British Columbia, Vancouver, Canada.
J Gordon Millichap
doaj +1 more source

