Results 101 to 110 of about 14,619 (195)

¹H NMR Chemical Shifts and J‐Coupling Constants Dependence on Temperature and pH: Implications for the Quantification of Relevant Metabolites

open access: yesNMR in Biomedicine, Volume 39, Issue 3, March 2026.
1H MRS, in combination with quantification methods using model functions based on prior knowledge of chemical shifts and coupling constants, allows the determination of characteristic metabolic processes in healthy and diseased tissue. Using the functional relationships δpHT$$ \delta \left( pH,T\right) $$ and JpHT$$ J\left( pH,T\right) $$ enables this ...
Felizitas C. Wermter   +2 more
wiley   +1 more source

Noninvasive 11.7‐T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure

open access: yesNMR in Biomedicine, Volume 39, Issue 3, March 2026.
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila   +10 more
wiley   +1 more source

A Novel Homozygous Variant in the Aspartoacylase Gene Causes Canavan Disease-Case Report

open access: yesJournal of Pediatric Research
Glu178 is the active site residue essential for substrate affinity and catalytic activity of the aspartoacylase enzyme. Sanger sequencing in an infant with Canavan disease revealed a homozygous ASPA: c.532G>A: p. (Glu178Lys) variant.
Archana Vaddinahalli Kariyappa   +7 more
doaj   +1 more source

Lithium from mood stabilizer to putative cognitive enhancer [PDF]

open access: yes, 2016
This study is the first to have demonstrated, by means of a highly sensitive test of visual memory, a potential hippocampus neuroprotective effect of lithium in patients with BD. Undoubtedly, other studies are needed to finally recognize lithium as a
Bersani, Giuseppe   +2 more
core   +2 more sources

Catatonia an Unexpected Side Effect of Electroconvulsive Therapy: A Case Report

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
This case report highlights an unexpected development of catatonia following electroconvulsive therapy in a patient with schizoaffective disorder. The catatonia resolved promptly after discontinuing psychotropic interventions, emphasizing the need for careful monitoring during ECT, especially in patients with complex psychiatric histories.
Fatemeh sheikhmoonesi   +3 more
wiley   +1 more source

Cingulate metabolites during pain and morphine treatment as assessed by magnetic resonance spectroscopy

open access: yesJournal of Pain Research, 2014
Tine Maria Hansen,1 Anne Estrup Olesen,2 Carsten Wiberg Simonsen,1 Asbjørn Mohr Drewes,2,3 Jens Brøndum Frøkjær11Mech-Sense, Department of Radiology, 2Mech-Sense, Department of Gastroenterology, 3Center for Sensory-Motor ...
Hansen TM   +4 more
doaj  

Multimodal machine learning for surgical decision support in epilepsy: Current evidence and translational gaps

open access: yesEpilepsia, Volume 67, Issue 3, Page 1118-1131, March 2026.
Abstract Objective This systematic review synthesizes evidence on multimodal machine learning (ML) decision support systems for epilepsy surgery focusing on postsurgical outcome prediction, with emphasis on methodological quality and implications for clinical practice.
Mattia Mercier   +2 more
wiley   +1 more source

Metabolic changes in concussed American football players during the acute and chronic post-injury phases [PDF]

open access: yes, 2011
Background Despite negative neuroimaging findings many athletes display neurophysiological alterations and post-concussion symptoms that may be attributable to neurometabolic alterations.
Luke C Henry   +6 more
core   +2 more sources

N-acetylaspartate: Genomics, phenomics and metabonomics

open access: yes, 2018
N-acetylaspartate (NAA) is the second most abundant metabolite in the brain. Its physiological roles have eluded researchers for sixty years and hypotheses on its functions are contentious. Clinical evidence suggests both absence and accumulation of NAA are poorly tolerated. Hypoacetylaspartia is caused by a null-mutation of the NAA-synthesizing enzyme
openaire   +2 more sources

Chorioamnionitis and Early Brain Development

open access: yesPediatric Neurology Briefs, 2009
The association of chorioamnionitis and early postnatal risk factors for white matter injury (WMI) and its effect on early brain development were determined in a study at University of British Columbia, Vancouver, Canada.
J Gordon Millichap
doaj   +1 more source

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