Results 91 to 100 of about 15,535,889 (203)

Total Synthesis of Native 5,7-Diacetylpseudaminic Acid from N-Acetylneuraminic Acid [PDF]

, 2016
The pseudaminic acids are a family of 5,7-diamino-3,5,7,9-tetradeoxynonulosonic acids that are functional components of flagellin and pili proteins within clinically relevant Gram-negative bacteria.
Williams, James T, Williams, James T., Payne, Richard, Payne, Richard J., Kiefel, Milton, Kiefel, Milton J., Kiefel, Milton J, Payne, Richard J, Corcilius, Leo   +8 more
core   +1 more source

N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

Frontiers in Immunology, 2019
The two major sialic acids described in mammalian cells are the N-glycolylneuraminic acid (Neu5Gc) and the N-acetylneuraminic acid (Neu5Ac). Neu5Gc synthesis starts from the N-acetylneuraminic acid (Neu5Ac) precursor modified by an hydroxylic group ...
Andrea Perota, Cesare Galli, Cesare Galli   +2 more
doaj   +1 more source

Effect of Intramolecular Hydrogen Bonds on the Binding Efficiency of Compounds Containing Aminoalcohol‐Based Subunits in Combination with Heterocyclic Groups

European Journal of Organic Chemistry, Volume 29, Issue 29, 7 August 2026.
This study broadens our understanding of the role of intramolecular interactions in molecular recognition and highlights the importance of considering their formation when designing artificial receptors, new drugs, and related systems. Aminoalcohols represent an important class of compounds and serve as building blocks for numerous biologically active ...
Manuel Stapf, Monika Mazik
wiley   +1 more source

Synthesis of Molecularly Imprinted Polymerand its Molecular Recognition Propertiesof N-Acetylneuraminic Acid

E-Journal of Chemistry, 2007
A molecular imprinting technique was applied in this work to detect N-acetylneuraminic acid (Neu5Ac) and its analogue structure. Twomolecularly imprinted polymers (MIP) were prepared using Neu 5Ac as the template molecule, as well as methacrylic acid ...
Hsin-Hung Pan, Wen-Chien Lee, Chin-Yin Hung, Ching-Chiang Hwang   +3 more
doaj   +1 more source

N-Acetylneuraminic Acid Inhibits Melanogenesis via Induction of Autophagy

Cosmetics
N-acetylneuraminic acid (Neu5Ac) is the predominant form of sialic acid present in the glossy swiftlet (Collocalia esculenta). It is also the only form of sialic acid detected in the human body.
Kei Yoshikawa, Kazuhisa Maeda
doaj   +1 more source

Migration of O-acetyl groups in N,O-acetylneuraminic acids [PDF]

, 1987
Highly purified N-acetyl-4-O-acetylneuraminic acid (Neu4,5Ac2), N-acetyl-7-O-acetylneuraminic acid (Neu5,7Ac2) and N-acetyl-7,9-di-O-acetylneuraminic acid (Neu5,7,9Ac3) were used to study spontaneous migrations of acetyl groups between hydroxyl groups ...
Schauer, R., Stoll, S., Shukla, Ashok K., Vliegenthart, J.F.G., Kamerling, J.P., Halbeek, H. van   +5 more
core  

Reaction of N-acetylneuraminic acid derivatives with perfluorinated anhydrides : a short access to N-perfluoracylated glycals with antiviral properties

, 2010
An efficient short protocol for the preparation of N-perfluoroacylated glycals of neuraminic acid, by simple short treatment of differently protected N-acetylneuraminic acid with perfluorinated anhydrides in acetonitrile at 135 °C, is reported, together ...
M. Anastasia, R. Mattina, P. Allevi, P. Rota   +3 more
core   +1 more source

Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation [PDF]

, 2015
The authors acknowledge the support of the Biotechnology and Biological Sciences Research Council (BBSRC), this research was partly funded by the BBSRC Institute Strategic Programme for The Gut Health and Food Safety (BB/J004529/1) and by the BB/L008602 ...
Vos, W.M., de, Hardy-Goddard, Jemma, Crost, Emmanuelle H., de Vos, Willem M., Gall, G., Le, Taylor, Garry L., Walshaw, J., Tailford, L.E., Crost, E.H., Taylor, G.L., Juge, N., Owen, C.D., Tailford, Louise E., Owen, C. David, Le Gall, G., Le Gall, Gwenaelle, Hardy-Goddard, J., Juge, Nathalie, Walshaw, John, de Vos, W.M.   +19 more
core   +1 more source

Diastereocontrolled Synthesis of Carbon Glycosides of N-Acetylneuraminic Acid via Glycosyl Samarium(III) Intermediates

, 2016
Diastereocontrolled Synthesis of Carbon Glycosides of N-Acetylneuraminic Acid via Glycosyl Samarium(III ...
Petinka I. Vlahova (1838632), Iontcho R. Vlahov (2293993), Robert J. Linhardt (710659)   +2 more
core   +1 more source

Chemical Communications / Distinguishing N-acetylneuraminic acid linkage isomers on glycopeptides by ion mobility-mass spectrometry [PDF]

, 2016
in deutscher Sprache nicht verfügbarDifferentiating the structure of isobaric glycopeptides represents a major challenge for mass spectrometry-based characterisation techniques.
Seeberger, PH, Pagel, Kevin, Pagel, K, Kolarich, D, Hofmann, Johanna, Varon Silva, Daniel, Kolarich, Daniel, Altmann, F, Altmann, Friederich, Struwe, WB, Hofmann, J, Seeberger, Peter H., Varón Silva, D., Thader, Andreas, Hinneburg, Hannes, Pagel, K., Kolarich, D., Struwe, Weston B., Hofmann, J., Seeberger, P., Seeberger, P. H., Hinneburg, H., Struwe, W., Hinneburg, H, Struwe, W. B., Altmann, F., Thader, A, Thader, A., Silva, D Varon   +28 more
core   +1 more source