Results 81 to 90 of about 1,001,057 (271)
PROTEOMICS, EarlyView.ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir +4 more
wiley +1 more source
Role of sialic acid in brachyspira hyodysenteriae adhesion to pig colonic mucins [PDF]
, 2019 Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins. Infection regulates mucin O-glycosylation in the colon and increases mucin secretion as
Haesebrouck, Freddy +3 more
core +2 more sources
Sialylation in Colorectal Cancer Rewires Antitumor Immunity at the Peritoneal Metastatic Site
European Journal of Immunology, Volume 56, Issue 5, May 2026.This study shows that loss of sialylation in CT26 cells reduces peritoneal tumor burden, correlating with a lower peritoneal cancer index score. These tumors exhibited increased immune infiltration with prominent alterations in the myeloid compartment and immune cell correlations unique to desialylated tumors, indicating profound reshaping of antitumor
Irene van der Haar Àvila +8 more
wiley +1 more source
Label-free mass spectrometry proteome quantification of human embryonic kidney cells following 24 hours of sialic acid overproduction [PDF]
, 2013 Peer ...
Joenväärä, Sakari +3 more
core +1 more source
Overproduction of N-Acetylneuraminic Acid (Sialic Acid) by Sialuria Fibroblasts [PDF]
Pediatric Research, 1985 Fibroblasts from the original sialuria patient are shown to contain high levels of free sialic acid, i.e., an average of 87 versus a normal average of 2 nmol/mg of protein. Gas liquid chromatography-mass spectrometry analysis confirmed that the accumulated material is N-acetylneuraminic acid.
G H, Thomas, L W, Reynolds, C S, Miller
openaire +2 more sources
Food Science &Nutrition, Volume 14, Issue 5, May 2026.This study reveals that edible bird's nest (EBN) and sialic acid (SA) efectively reverse sepsis‐induced immunosuppression. EBN and SA enhance T cell proliferation via the activation of the mTOR signaling pathway, and this enhanced proliferation mediates the protective effect.
Shentang Li +9 more
wiley +1 more source
Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]
, 2016 There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico +9 more
core +2 more sources
Molecular Characterization of a Novel N-Acetylneuraminate Lyase from a Deep-Sea Symbiotic Mycoplasma
Marine Drugs, 2018 N-acetylneuraminic acid (Neu5Ac) based novel pharmaceutical agents and diagnostic reagents are highly required in medical fields. However, N-acetylneuraminate lyase（NAL）for Neu5Ac synthesis is not applicable for industry due to its low catalytic ...
Shao-lu Wang +6 more
doaj +1 more source
Lipase-catalyzed acetylation of N-acetylneuraminic acid deiivative [PDF]
Bioorganic & Medicinal Chemistry Letters, 1999 A facile preparation of triacetylated derivative of 2-phenylthioglycoside of N-acetylneuraminic acid (4) was achieved by treatment with lipase PS in vinyl acetate. The major product 4 has a free hydroxyl group at C-7. Results of time-course HPLC analysis indicate that the reactivity of the hydroxyl groups under this condition is in the following order;
Lo, Lee-Chiang +3 more
openaire +3 more sources
Environmental Microbiology, Volume 28, Issue 5, May 2026.The human gut outer mucus layer hosts specific microbes. Using a synthetic mucin glycan‐degrading microbial community to mimic this mucosal microbiome, we show that mucin type affects microbial community composition, glycan degradation and metabolite production.
Maryse D. Berkhout +5 more
wiley +1 more source