Results 61 to 70 of about 1,001,057 (271)

Characterization of gangliosides by direct inlet chemical ionization mass spectrometry.

Journal of Lipid Research, 1984
Permethylated derivatives of N-acetylneuraminic acid-containing GM3, N-glycolylneuraminic acid-containing GM3, GD1a, and GD1b, were analyzed by direct inlet ammonia chemical ionization (CI) mass spectrometry.
T Argia, R K Yu, T Miyatake
doaj   +1 more source

Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus. [PDF]

, 2017
Sialic acids (Sias) are important glycans displayed on the cells and tissues of many different animals and are frequent targets for binding and modification by pathogens, including influenza viruses.
Ajit Varki, Brian R. Wasik, Colin R. Parrish, Daniel R. Perez, Hai Yu, Karen N. Barnard, Kurtis H. Feng, Robert J. Ossiboff, W. Paul Duprex, Xi Chen, Zahra Khedri   +10 more
core   +3 more sources

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis

Pathogens, 2023
The sugar molecule N-glycolylneuraminic acid (Neu5Gc) is one of the most common sialic acids discovered in mammals. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) catalyses the conversion of N-acetylneuraminic acid (Neu5Ac) to Neu5Gc ...
Oluwamayowa Joshua Ogun, Opeyemi S. Soremekun, Georg Thaller, Doreen Becker   +3 more
doaj   +1 more source

N-Acetylneuraminic acid attenuates hypercoagulation on high fat diet-induced hyperlipidemic rats

Food & Nutrition Research, 2015
Background and objective: N-Acetylneuraminic acid (Neu5Ac), a type of sialic acid, has close links with cholesterol metabolism and is often used as a biomarker in evaluating the risk of cardiovascular diseases.
Zhang Yida, Mustapha Umar Imam, Maznah Ismail, WaiTeng Wong, Maizaton Atmadini Abdullah, Aini Ideris, Norsharina Ismail   +6 more
doaj   +1 more source

N-Acetylneuraminic Acid (NANA) in Measles Virus

Experimental Biology and Medicine, 1978
The envelope glycoproteins and glycolipids of paramyxoviruses appear to be derived from the host cell plasma membrane during viral release (1, 2). Measles envelope glycoprotein spikes effect attachment of the virion to cell surfaces, thereby initiating either he-magglutination (HA) or infection (3,4).
P, Dore-Duffy, C, Howe
openaire   +2 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Sialic Acid Mutarotation Is Catalyzed by the Escherichia coli β-Propeller Protein YjhT [PDF]

, 2008
The acquisition of host-derived sialic acid is an important virulence factor for some bacterial pathogens, but in vivo this sugar acid is sequestered in sialoconjugates as the {alpha}-anomer.
Leech, Andrew, Müller, Axel, Potts, Jennifer R., Severi, Emmanuele, Thomas, Gavin H., Williamson, David, Wilson, Keith S.   +6 more
core   +1 more source

Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]

, 2012
BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L, Matthias, Michael A, Ricaldi, Jessica N, Vinetz, Joseph M   +3 more
core   +3 more sources

(1R,2R,3S,4R)-1-(Acetylamino)-2,4,5-tris(acetyloxy)-1-((2S)-4-(benzyloxy)-5-oxo-2,5-dihydrofuran-2-yl)pentan-3-yl Acetate

Molbank, 2022
Treatment of N-acetylneuraminic acid with excess base in the presence of benzyl bromide gives a polyhydroxylated 1,4 lactone which after acetylation gave the title compound in 20% overall yield.
Liam S. Fitzgerald, Ciaran O’Malley, Paul V. Murphy   +2 more
doaj   +1 more source

High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats

Journal of Biomedical Sciences, 2015
Serum sialic acid levels are positively correlated with coronary artery disease and inflammation. Although sialic acid is a non-specific marker, it is considered sensitive likely due to its influence in sialylation of glycoprotein structures all over the
Zhang Yida, M. Imam, M. Ismail, N. Ismail, A. Ideris, M. Abdullah   +5 more
semanticscholar   +1 more source