Results 61 to 70 of about 12,276 (167)

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

PROTEOMICS, Volume 26, Issue 7, Page 17-27, July 2026.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir, Karina Biskup, Michael Sittinger, Rudolf Tauber, Véronique Blanchard   +4 more
wiley   +1 more source

N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

Frontiers in Immunology, 2019
The two major sialic acids described in mammalian cells are the N-glycolylneuraminic acid (Neu5Gc) and the N-acetylneuraminic acid (Neu5Ac). Neu5Gc synthesis starts from the N-acetylneuraminic acid (Neu5Ac) precursor modified by an hydroxylic group ...
Andrea Perota, Cesare Galli, Cesare Galli   +2 more
doaj   +1 more source

Modular Molecular Design and Self‐Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels

Small, Volume 22, Issue 39, 13 July 2026.
Saccharide‐appended cyclic dipeptides are designed and developed as building blocks for glycosidase‐responsive supramolecular hydrogels. Their aqueous self‐assembly enables β‐galactosidase‐triggered gel‐to‐sol and neuraminidase‐triggered sol‐to‐gel transition systems, highlighting their potential as glycosidase‐responsive soft materials for biomedical ...
Shintaro Sugiura, Ryuta Tanaka, Sayuri L. Higashi, Aya Shibata, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Masato Ikeda   +6 more
wiley   +1 more source

The Potential Role of Expression of HLA‐E and HLA‐G in Organ Xenotransplantation

Xenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT Xenotransplantation offers a promising solution to the shortage of human organs for transplantation but requires overcoming numerous immune responses—particularly those mediated by the innate immune system through natural killer (NK) cells and macrophages.
Jeffrey K. Sumbo, Xiaowei Hu, Eckhard Wolf, David K. C. Cooper, Leo H. Buhler   +4 more
wiley   +1 more source

Synthesis of Molecularly Imprinted Polymerand its Molecular Recognition Propertiesof N-Acetylneuraminic Acid

E-Journal of Chemistry, 2007
A molecular imprinting technique was applied in this work to detect N-acetylneuraminic acid (Neu5Ac) and its analogue structure. Twomolecularly imprinted polymers (MIP) were prepared using Neu 5Ac as the template molecule, as well as methacrylic acid ...
Hsin-Hung Pan, Wen-Chien Lee, Chin-Yin Hung, Ching-Chiang Hwang   +3 more
doaj   +1 more source

N-Acetylneuraminic Acid Inhibits Melanogenesis via Induction of Autophagy

Cosmetics
N-acetylneuraminic acid (Neu5Ac) is the predominant form of sialic acid present in the glossy swiftlet (Collocalia esculenta). It is also the only form of sialic acid detected in the human body.
Kei Yoshikawa, Kazuhisa Maeda
doaj   +1 more source

Species-specific N-glycan patterns in animal and human breast milk samples

Frontiers in Nutrition
The main components of milk are protein, fat and carbohydrates. Glycans are complex carbohydrate structures covalently bound to proteins and lipids or exist freely in solutions.
Davide Ret, Davide Ret, Salvatore Alessio Gentile, Johanna Rohrhofer, Larissa Koidl, Francesca Cozzi, Eva Untersmayr   +6 more
doaj   +1 more source

Increasing brain N-acetylneuraminic acid alleviates hydrocephalus-induced neurological deficits. [PDF]

CNS Neurosci Ther, 2023
Wang Z, Nie X, Gao F, Tang Y, Ma Y, Zhang Y, Gao Y, Yang C, Ding J, Wang X.   +9 more
europepmc   +1 more source

Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

BMC Immunology, 2019
Background The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However,
Raghubendra Singh Dagur, Amanda Branch-Woods, Saumi Mathews, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Yan Cheng, Shana M. Miles, Samuel J. Pirruccello, Channabasavaiah B. Gurumurthy, Santhi Gorantla, Larisa Y. Poluektova   +11 more
doaj   +1 more source

Analysis of the intramolecular 1,7-lactone of N-acetylneuraminic acid using HPLC-MS: relationship between detection and stability. [PDF]

Glycoconj J, 2023
La Rocca P, Lavota I, Piccoli M, Cirillo F, Ghiroldi A, Ciconte G, Pappone C, Allevi P, Rota P, Anastasia L.   +9 more
europepmc   +1 more source