Results 51 to 60 of about 15,535,889 (203)

Bioengineering of bacterial polymer inclusions catalyzing the synthesis of N-acetylneuraminic acid [PDF]

, 2013
N-Acetylneuraminic acid is produced by alkaline epimerization of N-acetylglucosamine to N-acetylmannosamine and then subsequent condensation with pyruvate catalyzed by free N-acetylneuraminic acid aldolase.
Hooks, David O., Blatchford, Paul A., Rehm, Bernd HA, Rehm, Bernd H.A., Hooks, David O, Blatchford, Paul A   +5 more
core   +1 more source

A New Procedure for Gangliosidic N-Acetylneuraminic Acid Analysis in Serum

The International Journal of Biological Markers, 1991
In this paper a method is presented which is suitable for the extraction, purification and analysis of serum gangliosides. The advantage in comparison with other previously published procedures is the complete extraction of sialoglycolipids without ...
R. Gornati, S. Rapelli, G. Montorfano, C. Cattaneo, B. Berra   +4 more
doaj   +1 more source

Versatile synthetic route to carbocyclic N-Acetylneuraminic acid and its derivatives

, 2018
Sialic acid (N-acetylneuraminic acid) is a carbohydrate that possess a nine carbon backbone, and it is often found at the termini of glycoconjugates in biological systems.
John R. Thompson, Pinto, BM, Bennet, AJ, Sankar Mohan, Andrew J. Bennet, Mohan, S, B. Mario Pinto, Thompson, JR   +7 more
core   +1 more source

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis

Pathogens, 2023
The sugar molecule N-glycolylneuraminic acid (Neu5Gc) is one of the most common sialic acids discovered in mammals. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) catalyses the conversion of N-acetylneuraminic acid (Neu5Ac) to Neu5Gc ...
Oluwamayowa Joshua Ogun, Opeyemi S. Soremekun, Georg Thaller, Doreen Becker   +3 more
doaj   +1 more source

Structural Insights into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution [PDF]

, 2010
The substrate specificity of Escherichia coli N-acetylneuraminic acid lyase was previously switched from the natural condensation of pyruvate with N-acetylmannosamine, yielding N-acetylneuraminic acid, to the aldol condensation generating N ...
Harman, Thomas A., Trinh, Chi H., Dennis, C., Thomas A. Harman, Campeotto, I., Pearson, Arwen R., Chi H. Trinh, Amanda H. Bolt, Phillips, S. E. V., Ivan Campeotto, Trinh, C. H., Campeotto, Ivan, Phillips, Simon E.V., Bolt, Amanda H., Berry, Alan, Caitriona Dennis, Arwen R. Pearson, Nelson, A., Pearson, A. R., Harman, T. A., Berry, A., Dennis, Caitriona, Nelson, Adam, Adam Nelson, Alan Berry, Simon E.V. Phillips   +25 more
core   +1 more source

Characterization of gangliosides by direct inlet chemical ionization mass spectrometry.

Journal of Lipid Research, 1984
Permethylated derivatives of N-acetylneuraminic acid-containing GM3, N-glycolylneuraminic acid-containing GM3, GD1a, and GD1b, were analyzed by direct inlet ammonia chemical ionization (CI) mass spectrometry.
T Argia, R K Yu, T Miyatake
doaj   +1 more source

Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando, Laora Boulo, Léonid Lavnevich, Elisa Teyssou, Stéphane Marot, Adélie Gothland, Jean‐Michel Guigner, Anne‐Geneviève Marcelin, Mickaël Ménand, Vincent Calvez, Matthieu Sollogoub   +10 more
wiley   +2 more sources

Interaction of a lectin from Psathyrella velutina mushroom with N-acetylneuraminic acid [PDF]

, 1999
A lectin from the fruiting body of Psathyrella velutina has been used as a specific probe for non-reducing terminal N-acetylglucosamine residues. We reveal in this report that P.
Saitoh, Takeshi, Ogawa, Haruko, Haruko Ueda, Ueda, Haruko, Kyoko Kojima, Takeshi Saitoh, Haruko Ogawa, Kojima, Kyoko   +7 more
core   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source

Free and bound forms of sialic acid in blood plasma of patients with chronic lymphocytic leukemia

Regulatory Mechanisms in Biosystems, 2015
The level of free and bound forms of sialic acids (SА) was investigated in chronic lymphocytic leukemia (CLL) and at different stages of receiving chemotherapy.
O. V. Netronina
doaj   +1 more source