Results 31 to 40 of about 15,535,889 (203)
Synthetic Strategy towards a Carbocyclic N-Acetylneuraminic Acid [PDF]
, 2022 In the study of glycosidases, a class of activity-based probes (ABPs), that are carbocyclic mimics of natural carbohydrates and can covalently bind the enzyme, have proven to be useful tools.
Wennekes, Tom +4 more
core +3 more sources
Facile synthesis of C5-azido derivatives of thiosialosides and 2,3-didehydro-5-N-acetylneuraminic acid (DANA) [PDF]
, 2023 Neuraminic acid (Neu5Ac, also known as sialic acid) is an important monosaccharide found in glycoproteins and glycolipids which plays a vital role in regulation of physiological functions and pathological conditions.
Manas, Jana +2 more
core +2 more sources
Comparison of sialic acid content in bovine and buffalo milk and meat
Revista Científica, 2023 Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. Two significant SIAs in mammals are N-acetyl-neuraminic acid (Neu5Ac) and N- glycolylneuraminic acid (Neu-5Gc).
Michela Contò +2 more
doaj +1 more source
Stem Cell Research, 2020 N-acetylneuraminic acid synthase (NANS), the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), is closely associated with infantile-onset severe developmental delay and skeletal dysplasia.
Qian Bu +10 more
doaj +1 more source
An Overview of the Importance and Value of Porcine Species in Sialic Acid Research
Biology, 2022 Humans frequently interact with pigs, whose meat is also one of the primary sources of animal protein. They are one of the main species at the center of sialic acid (Sia) research.
Oluwamayowa Joshua Ogun +2 more
doaj +1 more source
Synthesis of 4-O-Alkylated N-Acetylneuraminic Acid Derivatives [PDF]
, 2020 N-acetyl neuraminic acid (Neu5Ac) is a densely functionalized nine-carbon monosaccharide. It ubiquitously decorates the surface of mammalian cells were it is found in terminal positions of glycolipids and glycoproteins.
Emil, Johansson +2 more
core +1 more source
Single-channel measurements of an N-acetylneuraminic acid-inducible outer membrane channel in Escherichia coli [PDF]
, 2012 NanC is an Escherichia coli outer membrane protein involved in sialic acid (Neu5Ac, i.e., N-acetylneuraminic acid) uptake. Expression of the NanC gene is induced and controlled by Neu5Ac. The transport mechanism of Neu5Ac is not known.
Peneff, Caroline M. +4 more
core +1 more source
The effect of long-term moderate exercise on myocardial metabolome in rats
Chinese Journal of Physiology, 2023 Regular moderate physical exercise is beneficial for the cardiovascular system. Our prior study has demonstrated a long-term moderate exercise (4-week of 60-min 74.0% V̇O2max treadmill running) is optimal in protecting from exhaustive exercise-induced ...
Zheng Ping +3 more
doaj +1 more source
Estimation of Salivary and Serum Total Sialic Acid Levels in Periodontal Health and Disease [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Chronic gingivitis and periodontitis are inflammatory diseases. An important function of host sialic acid is to regulate innate immunity. The aim of the study was to assess the concentration of Total sialic acid (TSA) in saliva and serum ...
SUREKHA R RATHOD +3 more
doaj +1 more source
Scientific Reports, 2017 The design, synthesis and application of N-acetylneuraminic acid-derived compounds bearing anomeric sulfo functional groups are described. These novel compounds, which we refer to as sulfo-sialic acid analogues, include 2-decarboxy-2-deoxy-2-sulfo-N ...
Christopher J. Vavricka +9 more
doaj +1 more source