Results 31 to 40 of about 1,001,057 (271)

Prognostic Value of Elevated Levels of Plasma N-Acetylneuraminic Acid in Patients With Heart Failure

open access: yesCirculation: Heart Failure, 2021
Supplemental Digital Content is available in the text. Background: Cardiac sialylation is involved in a variety of physiological processes in the heart. Altered sialylation has been implicated in heart failure (HF) mice.
Chenze Li   +23 more
semanticscholar   +1 more source

Improved N‐acetylneuraminic acid bioproduction by optimizing pathway for reducing intermediate accumulation

open access: yesFood Bioengineering, 2022
N‐acetylneuraminic acid (NeuAc), which has been widely used as a nutraceutical and pharmaceutical intermediate, plays an important role in improving brain development and cognition while enhancing immunity. Bacillus subtilis, generally regarded as a food‐
Haoyu Guo   +6 more
doaj   +1 more source

Comparison of sialic acid content in bovine and buffalo milk and meat

open access: yesRevista Científica, 2023
Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. Two significant SIAs in mammals are N-acetyl-neuraminic acid (Neu5Ac) and N- glycolylneuraminic acid (Neu-5Gc).
Michela Contò   +2 more
doaj   +1 more source

Generation of an NANS homozygous knockout human induced pluripotent stem cell line by the insertion of GFP-P2A-Puro via CRISPR/Cas9 editing

open access: yesStem Cell Research, 2020
N-acetylneuraminic acid synthase (NANS), the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), is closely associated with infantile-onset severe developmental delay and skeletal dysplasia.
Qian Bu   +10 more
doaj   +1 more source

Corrigendum: Characterization of a novel N-acetylneuraminic acid lyase favoring industrial N-acetylneuraminic acid synthesis process. [PDF]

open access: yesSci Rep, 2017
Scientific Reports 5: Article number: 09341; published online: 23 March 2015; updated: 28 April 2017 The original version of this article contained an error in testing the kinetic parameters of CgNal towards pyruvate, in which the concentration of ManNAc (50 mM) was not in excess.
Ji W   +7 more
europepmc   +4 more sources

An Overview of the Importance and Value of Porcine Species in Sialic Acid Research

open access: yesBiology, 2022
Humans frequently interact with pigs, whose meat is also one of the primary sources of animal protein. They are one of the main species at the center of sialic acid (Sia) research.
Oluwamayowa Joshua Ogun   +2 more
doaj   +1 more source

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors [PDF]

open access: yes, 2014
Mammals express the sialic acids ​N-acetylneuraminic acid (​Neu5Ac) and ​N-glycolylneuraminic acid (​Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV). ​Neu5Gc is synthesized from ​Neu5Ac by the enzyme
Böhm, Raphael   +14 more
core   +1 more source

The effect of long-term moderate exercise on myocardial metabolome in rats

open access: yesChinese Journal of Physiology, 2023
Regular moderate physical exercise is beneficial for the cardiovascular system. Our prior study has demonstrated a long-term moderate exercise (4-week of 60-min 74.0% V̇O2max treadmill running) is optimal in protecting from exhaustive exercise-induced ...
Zheng Ping   +3 more
doaj   +1 more source

Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin

open access: yesData in Brief, 2016
The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice
Rongrong Dong   +13 more
doaj   +1 more source

Neuraminidase Activity in \u3cem\u3eDiplococcus pneumoniae\u3c/em\u3e [PDF]

open access: yes, 1966
Kelly, R. T. (Marquette University School of Medicine, Milwaukee, Wis.), D. Greiff, and S. Farmer. Neuraminidase activity in Diplococcus pneumoniae. J. Bacteriol. 91:601–603.
ADA G. L.   +9 more
core   +2 more sources

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