Results 121 to 130 of about 836,707 (292)

N-Acetylneuraminic Acid Inhibits Melanogenesis via Induction of Autophagy

Cosmetics
N-acetylneuraminic acid (Neu5Ac) is the predominant form of sialic acid present in the glossy swiftlet (Collocalia esculenta). It is also the only form of sialic acid detected in the human body.
Kei Yoshikawa, Kazuhisa Maeda
doaj   +1 more source

B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen [PDF]

, 2018
Analysis of non-Gal antibody induced after pig-to-baboon cardiac xenotransplantation identified the glycan produced by porcine beta-1,4-N-acetyl-galactosaminyltransferase 2 (B4GALNT2) as an immunogenic xenotransplantation antigen.
Ahmad-Villiers, S, Byrne, G, Du, Z, McGregor, C   +3 more
core   +1 more source

Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates. [PDF]

, 2019
Dietary habits have been associated with alterations of the human gut resident microorganisms contributing to obesity, diabetes and cancer1. In Western diets, red meat is a frequently eaten food2, but long-term consumption has been associated with ...
Alisson-Silva, Frederico, Chang, Geoffrey, Chuzel, Léa, Diaz, Sandra L, Ganatra, Mehul B, Huang, Jianbo, Martino, Cameron, Rees, Steven D, Secrest, Patrick, Siegel, Dionicio, Taron, Christopher H, Varki, Ajit, Zaramela, Livia S, Zengler, Karsten, Zuñiga, Cristal   +14 more
core  

Erythrocytes from GGTA1/CMAH knockout pigs: implications for xenotransfusion and testing in non-human primates [PDF]

, 2014
Background Pig erythrocytes are potentially useful to solve the worldwide shortage of human blood for transfusion. Domestic pig erythrocytes, however, express antigens that are bound by human preformed antibodies.
Burlak, Christopher, Estrada, Jose L., Li, Ping, Tector, A. Joseph, Tector, Alfred, Tector, Matthew F., Wang, Zheng-Yu   +6 more
core   +1 more source

Increasing brain N-acetylneuraminic acid alleviates hydrocephalus-induced neurological deficits. [PDF]

CNS Neurosci Ther, 2023
Wang Z, Nie X, Gao F, Tang Y, Ma Y, Zhang Y, Gao Y, Yang C, Ding J, Wang X.   +9 more
europepmc   +1 more source

O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia

Journal of Experimental Medicine, 2013
Removal of 9-O-acetyl residues from the cell surface N-acetylneuraminic acid makes ALL cells drug sensitive.
Reshmi Parameswaran, M. Lim, A. Arutyunyan, H. Abdel-Azim, C. Hurtz, Kam Y. Lau, M. Müschen, R. Yu, M. von Itzstein, N. Heisterkamp, J. Groffen   +10 more
semanticscholar   +1 more source

Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans-An Evolutionary Perspective. [PDF]

, 2019
The glycocalyx of human cells differs from that of many other mammals by the lack of the sialic acid N-glycolylneuraminic acid (Neu5Gc) and increased abundance of its precursor N-acetylneuraminic acid (Neu5Ac).
Altman, Meghan O, Gagneux, Pascal
core   +1 more source

Интратекальная терапия при острой лимфобластной лейкемии и нейролейкемии у детей [PDF]

, 2017
Проводится оценка проведенной интратекальной терапии на состояние ГЭБ и ЦСЖ по панели биомаркеров при острой лимфобластной лейкемии и нейролейкемией у детей в динамике наблюдения и определение их диагностической и прогностической значимости при ...
Джаныбекова, И. А.
core   +2 more sources

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

Львівський клінічний вісник, 2019
Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the ...
Pliatsko M.
doaj   +1 more source

Analysis of the intramolecular 1,7-lactone of N-acetylneuraminic acid using HPLC-MS: relationship between detection and stability. [PDF]

Glycoconj J, 2023
La Rocca P, Lavota I, Piccoli M, Cirillo F, Ghiroldi A, Ciconte G, Pappone C, Allevi P, Rota P, Anastasia L.   +9 more
europepmc   +1 more source