Results 141 to 150 of about 15,535,889 (203)

Untargeted Metabolomics Analysis Reveals Potential Metabolic Targets in Gemcitabine-Treated Pancreatic Cancer Cells. [PDF]

Metabolites
Tiwari AP, Rushing BR, Silva L, Sumner SJ, Mukherjee P.   +4 more
europepmc   +1 more source

Pre-diagnostic metabolites in peripheral blood of Langerhans cell histiocytosis children with posterior pituitary involvement. [PDF]

Metabolomics
Li N, Zhao X, Shi L, Ma H, Lian H, Ren N, Wang D, Cui L, Zhang L, Zhao Y, Zhang L, Yang Y, Wang C, Song W, Wang T, Zhang R, Li Z.   +16 more
europepmc   +1 more source

Studies on the glycosylation of N-acetylneuraminic acid

, 1987
openaire   +1 more source

The first synthesis of N-acetylneuraminic acid 1,7-lactone

Chemical Communications, 2008
N -Acetylneuraminic acid is transformed into its until now unavailable and rather unwieldy 1,7-lactone, via the manageable 2-benzyloxycarbonyl N -acetylneuraminic acid 1,7-lactone which generates the free lactone in quantitative ...
R. Colombo, M. Anastasia, P. Rota, P. Allevi   +3 more
openaire   +4 more sources

Asymmetric synthesis of N-acetylneuraminic acid

Chemical Communications, 2000
A highly diastereoselective synthesis of N-acetylneuraminic acid 1 has been completed by stereoselective functionalization of cis-olefin 6 and trans-olefin 10 via intramolecular phenylselenoamidation and osmylation, respectively.
Sung Ho Kang, Hyeong-wook Choi, Joon Seop Kim, Joo-Hack Youn   +3 more
core   +3 more sources

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The biosynthesis of N-acetylneuraminic acid

Biochemical and Biophysical Research Communications, 1961
Abstract This communication describes a new enzyme system which catalyzes the synthesis of N -acetylneuraminic acid (NANA) from N -acetylmannosamine and phosphoenolpyruvic acid in the presence of ATP. It differs from N -acetylneuraminic acid aldolase (Comb and Roseman, 1960) which catalyzes the synthesis of NANA from N ...
L, WARREN, H, FELSENFELD
openaire   +2 more sources

Configuration of N-acetylneuraminic Acid

Nature, 1958
RECENTLY, Comb and Roseman1 observed that N-acetyl-d-mannosamine and not N-acetyl-d-glucosamine was a substrate for the enzyme synthesizing N-acetylneuraminic acid (nanaldolase) isolated from Clostridium perfringens. These results seem to be in conflict with the synthesis of N-acetylneuramic acid from N-acetyl-d-glucosamine as reported by Corn-forth ...
J, BRUG, G B, PAERELS
openaire   +2 more sources

Synthesis of N-acetylneuraminic acid

Experientia, 1963
Die Synthese der N-Acetylneuraminsaure aus N-Acetylmannosamin und Oxalessigsaure und die Isolierung eines Zwischenproduktes, 2-Keto-3-deoxy-3-carboxy-5-N-acetylnonulosaminsaure wird beschrieben.
H, RINDERKNECHT, T, REBANE
openaire   +2 more sources

An efficient process for production of n-acetylneuraminic acid using n-acetylneuraminic acid aldolase

Enzyme and Microbial Technology, 1997
N-acetyl-D-neuraminic acid (Neu5Ac) aldolase (EC 4.1.3.3) has bee reported for synthesis of Neu5Ac,1-5 but there are no reports of processes which do not have significant drawbacks for large-scale operation. Here, Neu5Ac aldolase from an overexpressing recombinant strain of Escherichia coli has been used to develop an immobilized enzyme process for ...
M, Mahmoudian, D, Noble, C S, Drake, R F, Middleton, D S, Montgomery, J E, Piercey, D, Ramlakhan, M, Todd, M J, Dawson   +8 more
openaire   +2 more sources

N-Acetylneuraminic Acid: Neoglycoproteins and Pseudopolysaccharides

Journal of Carbohydrate Chemistry, 1987
Abstract A simplified procedure for the synthesis of acetochloroneuraminic acid is described starting from the methyl ester. N-acetyl neuraminic acid α-allyl glycoside was prepared in high yield using silver salicylate as catalyst. Reductive ozonolysis of the allyl group, followed by direct reductive ami nation to protein carriers, gave immunogenic ...
Roy, René, Laferrière, Craig A., Gamian, Andrzej, Jennings, Harold J.   +3 more
openaire   +2 more sources