Results 51 to 60 of about 809,751 (208)
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang +5 more
wiley +2 more sources
Free and bound forms of sialic acid in blood plasma of patients with chronic lymphocytic leukemia
Regulatory Mechanisms in Biosystems, 2015 The level of free and bound forms of sialic acids (SА) was investigated in chronic lymphocytic leukemia (CLL) and at different stages of receiving chemotherapy.
O. V. Netronina
doaj +1 more source
Macromolecular Rapid Communications, EarlyView.Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley +1 more source
Molecular Characterization of a Novel N-Acetylneuraminate Lyase from a Deep-Sea Symbiotic Mycoplasma
Marine Drugs, 2018 N-acetylneuraminic acid (Neu5Ac) based novel pharmaceutical agents and diagnostic reagents are highly required in medical fields. However, N-acetylneuraminate lyase（NAL）for Neu5Ac synthesis is not applicable for industry due to its low catalytic ...
Shao-lu Wang +6 more
doaj +1 more source
Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
Mass Spectrometry Reviews, EarlyView.ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source
Journal of Lipid Research, 1970 A method is described for analysis of gangliosides by GLC assay of the sialic acid component. Mild acid treatment in methanol converted the latter to methyl ketoside methyl ester, which was then chromatographed as the TMS derivative.
ROBERT K. YU, ROBERT W. LEDEEN
doaj +1 more source
Overproduction of N-Acetylneuraminic Acid (Sialic Acid) by Sialuria Fibroblasts [PDF]
Pediatric Research, 1985 Fibroblasts from the original sialuria patient are shown to contain high levels of free sialic acid, i.e., an average of 87 versus a normal average of 2 nmol/mg of protein. Gas liquid chromatography-mass spectrometry analysis confirmed that the accumulated material is N-acetylneuraminic acid.
G H, Thomas, L W, Reynolds, C S, Miller
openaire +2 more sources
SusMat, EarlyView.The study uses rapidly prepared Cr NPs with controllable fluorescence, enabling co‐regulation of quenching and enhancement for dyes and DNA of differing structures. By assembling a CD63‐specific aptamer with Cr NPs, it creates a quantitative readout for CD63‐positive TDEs.
Meng Yao Wu +5 more
wiley +1 more source
Cell Proliferation, EarlyView.Decreased sialic acid increases the adhesion of RBC membranes to immunoglobulins leading to an increased erythrocyte sedimentation rate (ESR). The increase in reactive oxygen species (ROS) damages the sialic acid glycosyl chains on the surface of RBC membrane proteins, causing the membrane proteins to be overexposed to the plasma environment due to the
Sicheng Bian +16 more
wiley +1 more source
Journal of reproduction and development, 2015 Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) are new tools for producing gene knockout (KO) animals. The current study reports produced genetically modified pigs, in which two endogenous genes were knocked out.
S. Miyagawa +14 more
semanticscholar +1 more source