Results 61 to 70 of about 836,707 (292)

Characterization of gangliosides by direct inlet chemical ionization mass spectrometry.

Journal of Lipid Research, 1984
Permethylated derivatives of N-acetylneuraminic acid-containing GM3, N-glycolylneuraminic acid-containing GM3, GD1a, and GD1b, were analyzed by direct inlet ammonia chemical ionization (CI) mass spectrometry.
T Argia, R K Yu, T Miyatake
doaj   +1 more source

Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]

, 2012
BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L, Matthias, Michael A, Ricaldi, Jessica N, Vinetz, Joseph M   +3 more
core   +3 more sources

N-Acetylneuraminic Acid (NANA) in Measles Virus

Experimental Biology and Medicine, 1978
The envelope glycoproteins and glycolipids of paramyxoviruses appear to be derived from the host cell plasma membrane during viral release (1, 2). Measles envelope glycoprotein spikes effect attachment of the virion to cell surfaces, thereby initiating either he-magglutination (HA) or infection (3,4).
C. Howe, P. Dore-Duffy
openaire   +3 more sources

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis

Pathogens, 2023
The sugar molecule N-glycolylneuraminic acid (Neu5Gc) is one of the most common sialic acids discovered in mammals. Cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) catalyses the conversion of N-acetylneuraminic acid (Neu5Ac) to Neu5Gc ...
Oluwamayowa Joshua Ogun, Opeyemi S. Soremekun, Georg Thaller, Doreen Becker   +3 more
doaj   +1 more source

Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives [PDF]

, 2017
Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases).
Andrew Bell, Angata, Bednarski, Chen, Chokhawala, Chokhawala, Crost, Crost, Dimitrios Latousakis, Etzold, Furuhata, Gerardy-Schahn, Gwenaelle Le Gall, Hai Yu, Ian J. Colquhoun, Juge, Juge, Lee, Lewis, Li, Li, Lifely, Louise E. Tailford, Luo, Luo, Marie Monestier, Martin Rejzek, Nathalie Juge, Ouwerkerk, Robert A. Field, Rohrer, Sandra Tribolo, Savage, Schauer, Schroder, Simone Dedola, Suzuki, Tailford, Tailford, Varki, Xi Chen, Yu   +41 more
core   +1 more source

(1R,2R,3S,4R)-1-(Acetylamino)-2,4,5-tris(acetyloxy)-1-((2S)-4-(benzyloxy)-5-oxo-2,5-dihydrofuran-2-yl)pentan-3-yl Acetate

Molbank, 2022
Treatment of N-acetylneuraminic acid with excess base in the presence of benzyl bromide gives a polyhydroxylated 1,4 lactone which after acetylation gave the title compound in 20% overall yield.
Liam S. Fitzgerald, Ciaran O’Malley, Paul V. Murphy   +2 more
doaj   +1 more source

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning

Journal of reproduction and development, 2016
Gene-knockout pigs hold great promise as a solution to the shortage of organs from donor animals for xenotransplantation. Several groups have generated gene-knockout pigs via clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR ...
Hanchao Gao, Chengjiang Zhao, Xi Xiang, Yong Li, Yanli Zhao, Zesong Li, D. Pan, Yifan Dai, H. Hara, D. Cooper, Z. Cai, Lisha Mou   +11 more
semanticscholar   +1 more source

Overproduction of N-Acetylneuraminic Acid (Sialic Acid) by Sialuria Fibroblasts [PDF]

Pediatric Research, 1985
Fibroblasts from the original sialuria patient are shown to contain high levels of free sialic acid, i.e., an average of 87 versus a normal average of 2 nmol/mg of protein. Gas liquid chromatography-mass spectrometry analysis confirmed that the accumulated material is N-acetylneuraminic acid.
George H. Thomas, Carol S. Miller, Linda W. Reynolds   +2 more
openaire   +3 more sources

Sialic acid acquisition in bacteria - one substrate many transporters [PDF]

, 2016
The sialic acids are a family of 9-carbon sugar acids found predominantly on the cell-surface glycans of humans and other animals within the Deuterostomes and are also used in the biology of a wide range of bacteria that often live in association with ...
Thomas, Gavin Hugh
core   +1 more source

Differential carbohydrate recognition by Campylobacter jejuni strain 11168: influences of temperature and growth conditions. [PDF]

PLoS ONE, 2009
The pathogenic clinical strain NCTC11168 was the first Campylobacter jejuni strain to be sequenced and has been a widely used laboratory model for studying C. jejuni pathogenesis. However, continuous passaging of C.
Christopher J Day, Joe Tiralongo, Regan D Hartnell, Carie-Anne Logue, Jennifer C Wilson, Mark von Itzstein, Victoria Korolik   +6 more
doaj   +1 more source