Results 81 to 90 of about 809,751 (208)

Species-specific N-glycan patterns in animal and human breast milk samples

Frontiers in Nutrition
The main components of milk are protein, fat and carbohydrates. Glycans are complex carbohydrate structures covalently bound to proteins and lipids or exist freely in solutions.
Davide Ret, Davide Ret, Salvatore Alessio Gentile, Johanna Rohrhofer, Larissa Koidl, Francesca Cozzi, Eva Untersmayr   +6 more
doaj   +1 more source

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

Львівський клінічний вісник, 2019
Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the ...
Pliatsko M.
doaj   +1 more source

Increasing brain N-acetylneuraminic acid alleviates hydrocephalus-induced neurological deficits. [PDF]

CNS Neurosci Ther, 2023
Wang Z, Nie X, Gao F, Tang Y, Ma Y, Zhang Y, Gao Y, Yang C, Ding J, Wang X.   +9 more
europepmc   +1 more source

Chemistry of N-Acetylneuraminic Acid (Neu5Ac)

Trends in Glycoscience and Glycotechnology, 2004
シアル酸 (Neu5Ac, Neu5Gc, andKDN) は単糖の中で最も複雑な構造もつ化合物である。シアル酸は分子量320程度の小さな分子にもかかわらず多くの官能基から構成されている。またそれらの官能基が条件によって糖特有の平衡状態とる。このことがシアル酸の合成化学を始めるにあたり難くしている。シアル酸は種々の試薬に大変敏感に反応する性質を持っているので、目的化合物を合成するには経験的な反応条件が必要となる。ここでは、既に報告されている沢山の論文の中からシアル酸の中で最も代表的なN-アセチルノイラミン酸についてNeu5Ac特有の反応と基本的な反応の紹介と、簡単な反応によるNeu5Acの挙動からその化学的な多様性について述べる。
openaire   +2 more sources

Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

BMC Immunology, 2019
Background The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However,
Raghubendra Singh Dagur, Amanda Branch-Woods, Saumi Mathews, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Yan Cheng, Shana M. Miles, Samuel J. Pirruccello, Channabasavaiah B. Gurumurthy, Santhi Gorantla, Larisa Y. Poluektova   +11 more
doaj   +1 more source

Analysis of the intramolecular 1,7-lactone of N-acetylneuraminic acid using HPLC-MS: relationship between detection and stability. [PDF]

Glycoconj J, 2023
La Rocca P, Lavota I, Piccoli M, Cirillo F, Ghiroldi A, Ciconte G, Pappone C, Allevi P, Rota P, Anastasia L.   +9 more
europepmc   +1 more source

N-Acetylneuraminic Acid Analogues

Journal of Biological Chemistry, 1971
Robert L. McLean, Maitree Suttajit, Janice Beidler, Richard J. Winzler   +3 more
openaire   +2 more sources

Crosstalk between Breast Milk N-Acetylneuraminic Acid and Infant Growth in a Gut Microbiota-Dependent Manner. [PDF]

Metabolites, 2023
Ouyang R, Zheng S, Wang X, Li Q, Ding J, Ma X, Zhuo Z, Li Z, Xin Q, Lu X, Zhou L, Ren Z, Mei S, Liu X, Xu G.   +14 more
europepmc   +1 more source

EFFECTS OF MODULATING NF ΚB AND NRF2 SIGNALING PATHWAYS ON THE DEPOLYMERIZATION OF CONNECTIVE TISSUE BIOPOLYMERS IN THE RAT SMALL INTESTINE UNDER SURGICAL TRAUMA FOLLOWING SINGLE PROLONGED STRESS

Проблеми екології та медицини
This study aimed to investigate the effects of ammonium pyrrolidinedithiocarbamate (an inhibitor of NF κB activation) and sulforaphane (an inducer of the Nrf2/antioxidant response element (ARE) signaling pathway) on the depolymerization processes of ...
R.M. Ryabushko, Z.O. Boiarska, V.O. Kostenko   +2 more
doaj   +1 more source

Neurodevelopmental defects in human cortical organoids with N-acetylneuraminic acid synthase mutation. [PDF]

Sci Adv, 2023
Bu Q, Dai Y, Zhang H, Li M, Liu H, Huang Y, Zeng A, Qin F, Jiang L, Wang L, Chen Y, Li H, Wang X, Zhao Y, Qin M, Zhao Y, Zhang N, Kuang W, Zhao Y, Cen X.   +19 more
europepmc   +1 more source