A method is described for analysis of gangliosides by GLC assay of the sialic acid component. Mild acid treatment in methanol converted the latter to methyl ketoside methyl ester, which was then chromatographed as the TMS derivative.
ROBERT K. YU, ROBERT W. LEDEEN
doaj +1 more source
Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) are new tools for producing gene knockout (KO) animals. The current study reports produced genetically modified pigs, in which two endogenous genes were knocked out.
S. Miyagawa+14 more
semanticscholar +1 more source
Role of sialic acid in brachyspira hyodysenteriae adhesion to pig colonic mucins [PDF]
Infection with Brachyspira hyodysenteriae results in mucoid hemorrhagic diarrhea. This pathogen is associated with the colonic mucus layer, mainly composed of mucins. Infection regulates mucin O-glycosylation in the colon and increases mucin secretion as
Haesebrouck, Freddy+3 more
core +2 more sources
In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino+6 more
wiley +1 more source
Label-free mass spectrometry proteome quantification of human embryonic kidney cells following 24 hours of sialic acid overproduction [PDF]
Peer ...
Joenväärä, Sakari+3 more
core +1 more source
Impact of N‐linked glycans on the dual short fibulin/LTBP‐4 axes regulating elastogenesis
Elastic fiber assembly is orchestrated by multiple glycoproteins. We delineate the molecular basis of two key axes involved in elastic fiber formation—LTBP‐4L/fibulin‐4 and LTBP‐4S/fibulin‐5. We show that N‐linked glycans on these glycoproteins regulate their interactions and conformations, both of which are critical aspects in elastic fiber formation.
Valentin Nelea+8 more
wiley +1 more source
Distribution of glycan motifs at the surface of midgut cells in the cotton leafworm (Spodoptera littoralis) demonstrated by lectin binding [PDF]
Glycans are involved in many biological phenomena, including signal transduction, cell adhesion, immune response or differentiation. Although a few papers have reported on the role of glycans in the development and proper functioning of the insect midgut,
Els J. M. Van Damme+5 more
core +2 more sources
Genetic Adaptation to Brackish Water and Spawning Season in European Cisco
ABSTRACT How species adapt to diverse environmental conditions is essential for understanding evolution and the maintenance of biodiversity. The European cisco (Coregonus albula) is a salmonid that occurs in both fresh and brackish water, and this together with the presence of sympatric spring‐ and autumn‐spawning lacustrine populations provides an ...
Qiaoling Deng+18 more
wiley +1 more source
Nitrogen assimilation by E. coli in the mammalian intestine
Nitrogen is an essential element for all living organisms, including Escherichia coli. Potential nitrogen sources are abundant in the intestine, but knowledge of those used specifically by E. coli to colonize remains limited. Here, we sought to determine
Sudhir Doranga, Tyrrell Conway
doaj +1 more source
Free and bound forms of sialic acid in blood plasma of patients with chronic lymphocytic leukemia
The level of free and bound forms of sialic acids (SА) was investigated in chronic lymphocytic leukemia (CLL) and at different stages of receiving chemotherapy.
O. V. Netronina
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