Results 101 to 110 of about 13,464,291 (195)

Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine

, 2017
Dimethyltryptamines are hallucinogenic serotonin-like molecules present in traditional Amerindian medicine (e.g.Ayahuasca)recently associated with cognitive gains, antidepressant effects and changes in brain areas related to attention.
Juliana Minardi Nascimento, Daniel Martins-de-Souza, Renata de Moraes Maciel, Draulio B. de Araujo, Rafaela Costa Sartore, Sidarta Ribeiro, Stevens Rehen, Vanja Dakic   +7 more
core   +1 more source

Computational evaluation of aluminum and zinc doped C20 fullerenes as advanced sensors for the detection of the narcotic dimethyltryptamine

Scientific Reports
N, N-Dimethyltryptamine (N, N-DMT) is a potent psychedelic substance whose detection is crucial in medical and forensic contexts. In this study, we computationally evaluate the potential of aluminum- and zinc-doped C20 fullerenes (AlC19 and ZnC19) as ...
Saad M. Alshahrani
doaj   +1 more source

Reaction of N,N‑Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions

ACS Omega, 2018
Lee E. Dunlap, David E. Olson
doaj   +1 more source

Optimized infusion rates for N,N-dimethyltryptamine to achieve a target psychedelic intensity based on a modeling and simulation framework. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2023
Eckernäs E, Koomen J, Timmermann C, Carhart-Harris R, Röshammar D, Ashton M.   +5 more
europepmc   +1 more source

Antinociceptive effect of N,N-dimethyltryptamine (DMT) involving serotonergic, opioidergic, cannabinoidergic, and nitrergic systems in PGE2-induced hyperalgesia in rats

1. Dos Santos RG, Hallak JEC. Ayahuasca: pharmacology, safety, and therapeutic effects. CNS Spectr. 2024 Nov 20;30(1):e2. 2. Bouso JC, González D, Fondevila S, Cutchet M, Fernández X, Ribeiro Barbosa PC, et al.
Flávia C.S. Fonseca, Daniel P.D. Machado, Igor D.G. Duarte, André D. Cavalcante, Andrea C. Perez, Thiago R.L. Romero   +5 more
core   +1 more source

sj-docx-1-jop-10.1177_02698811241246857 – Supplemental material for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants

Supplemental material, sj-docx-1-jop-10.1177_02698811241246857 for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N ...
Allan H. Young (5677769), Frank Wiegand (11800677), James Jonathan Rucker (18367867), Claire Roberts (3613646), Fiona Dunbar (11591210), Takahiro Yamamoto (159582), Ben Suttle (18367873), Mathieu Seynaeve (18367870), Anna O. Ermakova (18367876)   +8 more
core   +1 more source

sj-docx-2-jop-10.1177_02698811241246857 – Supplemental material for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants

Supplemental material, sj-docx-2-jop-10.1177_02698811241246857 for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N ...
Allan H. Young (5677769), Frank Wiegand (11800677), James Jonathan Rucker (18367867), Claire Roberts (3613646), Fiona Dunbar (11591210), Takahiro Yamamoto (159582), Ben Suttle (18367873), Mathieu Seynaeve (18367870), Anna O. Ermakova (18367876)   +8 more
core   +1 more source

<i>Incilius alvarius</i> Cell-Based Synthesis of 5-Methoxy-N,N-Dimethyltryptamine. [PDF]

Psychedelic Med (New Rochelle), 2023
Lerer L, Reynolds E, Varia J, Blakolmer K, Lerer B.   +4 more
europepmc   +1 more source

sj-docx-3-jop-10.1177_02698811241246857 – Supplemental material for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants

Supplemental material, sj-docx-3-jop-10.1177_02698811241246857 for Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N ...
Allan H. Young (5677769), Frank Wiegand (11800677), James Jonathan Rucker (18367867), Claire Roberts (3613646), Fiona Dunbar (11591210), Takahiro Yamamoto (159582), Ben Suttle (18367873), Mathieu Seynaeve (18367870), Anna O. Ermakova (18367876)   +8 more
core   +1 more source

Combined Neuroprotective Effects of N,N-Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats. [PDF]

J Neurochem
Aponte PAC, Montoya EH, Mazali IO, Sussulini A, Barraviera B, Ferreira RS, Cartarozzi LP, de Oliveira ALR.   +7 more
europepmc   +1 more source