Results 81 to 90 of about 13,464,291 (195)
DMT alters cortical travelling waves
eLife, 2020 Psychedelic drugs are potent modulators of conscious states and therefore powerful tools for investigating their neurobiology. N,N, Dimethyltryptamine (DMT) can rapidly induce an extremely immersive state of consciousness characterized by vivid and ...
Andrea Alamia +4 more
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Psilocybin as a novel treatment for chronic pain
British Journal of Pharmacology, Volume 183, Issue 14, Page 3992-4005, July 2026.Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey +3 more
wiley +1 more source
Behavioral effects of 5-methoxy-N:N-dimethyltryptamine, other tryptamines, and LSD
, 1962 The effect of 5-methoxy-N:N-dimethyltryptamine on the conditioned avoidance response of trained rats was compared quantitatively, using a shuttle-box, with that of several substituted tryptamines and LSD-25.
Peter K. Gessner, Irvine H. Page
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Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
British Journal of Pharmacology, Volume 183, Issue 14, Page 3935-3949, July 2026.Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Frontiers in Molecular BiosciencesIntroductionAyahuasca is a psychedelic preparation containing N,N-dimethyltryptamine (DMT) and the β-carboline harmine (HRM), a reversible monoamine oxidase A inhibitor that enables DMT oral bioavailability.
Gabriella de Souza Gomes Ribeiro +15 more
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N, N-dimethyltryptamine forms oxygenated metabolites via CYP2D6 - an in vitro investigation
, 2023 N, N-dimethyltryptamine (DMT) is a psychedelic compound that has shown potential in the treatment of depression. Aside from the primary role of monoamine oxidase A (MAO-A) in DMT metabolism, the metabolic pathways are poorly understood.
Alicia Macan-Schönleben (17344598) +5 more
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Parkinson's disease is a progressive neurodegenerative disorder with increasing global prevalence, primarily driven by population ageing. A hallmark of the disease is the degeneration of nigrostriatal dopaminergic neurons, accompanied by marked ...
Giné Domínguez, Elena +8 more
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Acta Crystallographica Section E: Crystallographic CommunicationsThe title compound, C12H16N2O, is a hydroxy-substituted monoamine alkaloid, and the primary metabolite of the naturally occurring psychedelic compound psilocybin.
Matthias Zeller +2 more
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Safety and tolerability profile of N,N-Dimethyltryptamine: a systematic review of clinical trials
N,N-Dimethyltryptamine (DMT) is presently emerging as a candidate in clinical trials aimed at addressing treatment-resistant depression. This condition is characterized by its chronic and incapacitating nature, featuring heightened severity and prolonged
Wiesław Jerzy Cubała +2 more
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Psychotria viridis: Chemical constituents from leaves and biological properties
Anais da Academia Brasileira de CiênciasThe phytochemical study of hexane, chloroform and methanol extracts from leaves of Psychotria viridis resulted in the identification of: the pentacyclic triterpenes, ursolic and oleanolic acid; the steroids, 24-methylene-cycloartanol, stigmasterol and β ...
DÉBORA B.S. SOARES +7 more
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