Results 11 to 20 of about 13,562,347 (304)

Serum N-Glycan Profiling Predicts Prognosis in Patients Undergoing Hemodialysis [PDF]

The Scientific World Journal, 2013
Background. The aim of this study is to evaluate the usefulness of serum N-glycan profiling for prognosis in hemodialysis patients. Methods. Serum N-glycan analysis was performed in 100 hemodialysis patients in June 2008 using the glycoblotting method ...
Shingo Hatakeyama, Maho Amano, Yuki Tobisawa, Tohru Yoneyama, Megumi Tsushima, Kazuko Hirose, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Hisao Saitoh, Kanemitsu Yamaya, Tomihisa Funyu, Shin-Ichiro Nishimura, Chikara Ohyama   +13 more
doaj   +2 more sources

N-Glycans in cancer progression [PDF]

Glycobiology, 2008
N-Glycan branching in the medial-Golgi generates ligands for lattice-forming lectins (e.g., galectins) that regulate surface levels of glycoproteins including epidermal growth factor (EGF) and transforming growth factor-beta (TGF-beta) receptors. Moreover, functional classes of glycoproteins differ in N-glycan multiplicities (number of N-glycans ...
Ken S, Lau, James W, Dennis
openaire   +2 more sources

Identification of novel high mannose N-glycan isomers undescribed by current multicellular eukaryotic biosynthetic pathways [PDF]

, 2022
N-linked glycosylation is one of the most important post-translational modifications of proteins. Current knowledge of multicellular eukaryote N-glycan biosynthesis suggests high mannose N-glycans are generated in the endoplasmic reticulum and Golgi ...
Charles Pin-Kuang, Lai, Chia Yen, Liew, Ting-Yi, Yang, An-Ti, Hung, Bryan John Abel, Magoling, Chi-Kung, Ni, Hong-Sheng, Luo   +6 more
core   +1 more source

Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies

iScience, 2020
Summary: HIV-1 envelope (Env) N-glycosylation impact virus-cell entry and immune evasion. How each glycan interacts to shape the Env-protein-sugar complex and affects Env function is not well understood.
Qing Wei, Audra A. Hargett, Barbora Knoppova, Alexandra Duverger, Reda Rawi, Chen-Hsiang Shen, S. Katie Farney, Stacy Hall, Rhubell Brown, Brandon F. Keele, Sonya L. Heath, Michael S. Saag, Olaf Kutsch, Gwo-Yu Chuang, Peter D. Kwong, Zina Moldoveanu, Milan Raska, Matthew B. Renfrow, Jan Novak   +18 more
doaj   +1 more source

The Structural Difference of Isobaric N-Glycans of Two Microalgae Samples Reveals Taxonomic Distance

Frontiers in Plant Science, 2021
Microalgae of the Chlorella clade are extensively investigated as an environmentally friendly source of renewable biofuels and high-value nutrients. In addition, essentially unprocessed Chlorella serves as wholesome food additive.
Réka Mócsai, Hanspeter Kaehlig, Markus Blaukopf, Johannes Stadlmann, Paul Kosma, Friedrich Altmann   +5 more
doaj   +1 more source

Database search assisted N-glycan structure identification [PDF]

, 2021
Capillary electrophoresis-based glycan separation and structure identification is one of the most frequently used tools in almost all fields of biological-medical research and biopharmaceutical manufacturing.
Szigeti, Marton, Szigeti, M, Jarvas, Gabor, Marton Szigeti, Andras Guttman, Gabor Jarvas, Campbell, Matthew P., Guttman, Andras, Guttman, A, Campbell, MP, Jarvas, G, Matthew P. Campbell   +11 more
core   +1 more source

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]

, 2009
Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine, Kozar, Tibor, Kojima, Shuji, Gabius, Hans-Joachim, Unverzagt, Carlo   +4 more
core   +1 more source

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds [PDF]

, 2013
This work was supported by a Wellcome Trust award to TMG.Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this ...
Brooks, Doug, Gloster, Tracey M., Vocadlo, D.J., Brooks, D., Kolarich, Daniel, Kermode, Allison R, Kermode, Allison R., Haselhorst, T., Qian, Y., Gloster, Tracey M, Qian, Yi, Gloster, Tracey, Kolarich, D., Haselhorst, Thomas, Packer, N.H., Pierce, Owen, He, X., von Itzstein, Mark, Gloster, T.M., Packer, Nicolle H., He, Xu, Pierce, O., Packer, Nicolle H, Vocadlo, David J, von Itzstein, M., Kermode, A.R., Vocadlo, David J.   +26 more
core   +1 more source

Ion-Mobility Mass Spectrometry of Glycans and Glycopeptides Using Both Intact and Glycan Sequencing Approaches In Positive Ion Mode Facilitates Glycan Isomer and Glycan Motif Identification [PDF]

, 2020
High resolution glycan analysis has become an important part of biopharmaceutical API production and quality control. Liquid chromatography (LC) is now a well-established technique in this field but the resolution of similar isomeric glycan structures is
Sabine, Flitsch, jien nee, tai, Edward, Pallister, Yuansheng, Yang, Say-Kong, Ng, Pauline, Rudd, Shi-Jie, Tay, ian, walsh, Matthew, Choo, Terry, Nguyen-Khuong   +9 more
core   +2 more sources

The N-glycan Glycoprotein Deglycosylation Complex (Gpd) from Capnocytophaga canimorsus Deglycosylates Human IgG [PDF]

, 2011
Author Summary Capnocytophaga canimorsus are Gram-negative bacteria from the normal oral flora of dogs and cats. They cause rare but severe infections in humans that have been bitten or simply licked by a dog or cat.
Suzette Moes, Paul Jenö, Cornelis, Guy R., Pablo Manfredi, Jenö, Paul, Manuela Mally, Guy R. Cornelis, Francesco Renzi, Guy R Cornelis, Renzi, Francesco, Mally, Manuela, Moes, Suzanne, Manfredi, Pablo   +12 more
core   +2 more sources