Results 31 to 40 of about 13,562,347 (304)

Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A Review

open access: yesMemorias do Instituto Oswaldo Cruz, 2010
Human malignant malaria is caused by Plasmodium falciparum and accounts for almost 900,000 deaths per year, the majority of which are children and pregnant women in developing countries.
Cristiana S de Macedo   +4 more
doaj   +1 more source

The Mechanism by which 146-N-Glycan Affects the Active Site of Neuraminidase. [PDF]

open access: yesPLoS ONE, 2015
One of the most conserved glycosylation sites of neuraminidase (NA) is 146-N-glycan. This site is adjacent to the 150-cavity of NA, which is found within the active site and thought to be a target for rational drug development against the antiviral ...
Pi Liu   +4 more
doaj   +1 more source

Glycan profiling shows unvaried N-glycomes in MSC clones with distinct differentiation potentials

open access: yesFrontiers in Cell and Developmental Biology, 2016
Different cell types have different N-glycomes in mammals. This means that cellular differentiation is accompanied by changes in the N-glycan profile. Yet when the N-glycomes of cell types with differing fates diverge is unclear. We have investigated the
Katherine Mary Wilson   +3 more
doaj   +1 more source

Glycan-specific RF model training performance is correlated with the number of training examples.

open access: yes, 2021
Training performance of glycan-specific RF models summarized by F2 scores combining recall and precision with greater emphasis on recall, plotted against the number of samples used in training each specific model.
Chris Bailey-Kellogg (682345)   +1 more
core   +1 more source

Biological significance of complex N-glycans in plants and their impact on plant physiology

open access: yesFrontiers in Plant Science, 2014
Asparagine (N)-linked protein glycosylation is a ubiquitous co- and post-translational modification which can alter the biological function of proteins and consequently affects the development, growth and physiology of organisms.
Richard eStrasser
doaj   +1 more source

Improved method for drawing of a glycan map, and the first page of glycan atlas, which is a compilation of glycan maps for a whole organism. [PDF]

open access: yesPLoS ONE, 2014
Glycan Atlas is a set of glycan maps over the whole body of an organism. The glycan map that includes data of glycan structure and quantity displays micro-heterogeneity of the glycans in a tissue, an organ, or cells. The two-dimensional glycan mapping is
Shunji Natsuka   +3 more
doaj   +1 more source

Characterization of recombinant human lactoferrin N-glycans expressed in the milk of transgenic cows.

open access: yesPLoS ONE, 2017
Lactoferrin (LF) is one of the most abundant bioactive glycoproteins in human milk. Glycans attached through N-glycosidic bonds may contribute to Lactoferrin functional activities. In contrast, LF is present in trace amounts in bovine milk.
Annabelle Le Parc   +5 more
doaj   +1 more source

Alteration of rhesus macaque serum N-glycome during infection with the human parasitic filarial nematode Brugia malayi

open access: yesScientific Reports, 2022
Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including infections, in humans.
Laudine M. C. Petralia   +10 more
doaj   +1 more source

A Method to the Madness of N-Glycan Complexity? [PDF]

open access: yesCell, 2007
Cell-surface glycoprotein receptors have varying numbers of N-glycan sites. In this issue of Cell, Lau et al. (2007) report that increasing intracellular UDP-GlcNAc leads to increased branching of N-glycans, increased receptor association with cell-surface galectin-3, and enhanced signaling.
openaire   +2 more sources

Identification and comparison of N-glycome profiles from common dietary protein sources

open access: yesFood Chemistry: X
The N-glycomes of bovine whey, egg white, pea, and soy protein isolates are described here. N-glycans from four protein isolates were analyzed by HILIC high performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (HILIC ...
Matthew Bolino   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy