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Human malignant malaria is caused by Plasmodium falciparum and accounts for almost 900,000 deaths per year, the majority of which are children and pregnant women in developing countries.
Cristiana S de Macedo +4 more
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The Mechanism by which 146-N-Glycan Affects the Active Site of Neuraminidase. [PDF]
One of the most conserved glycosylation sites of neuraminidase (NA) is 146-N-glycan. This site is adjacent to the 150-cavity of NA, which is found within the active site and thought to be a target for rational drug development against the antiviral ...
Pi Liu +4 more
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Glycan profiling shows unvaried N-glycomes in MSC clones with distinct differentiation potentials
Different cell types have different N-glycomes in mammals. This means that cellular differentiation is accompanied by changes in the N-glycan profile. Yet when the N-glycomes of cell types with differing fates diverge is unclear. We have investigated the
Katherine Mary Wilson +3 more
doaj +1 more source
Glycan-specific RF model training performance is correlated with the number of training examples.
Training performance of glycan-specific RF models summarized by F2 scores combining recall and precision with greater emphasis on recall, plotted against the number of samples used in training each specific model.
Chris Bailey-Kellogg (682345) +1 more
core +1 more source
Biological significance of complex N-glycans in plants and their impact on plant physiology
Asparagine (N)-linked protein glycosylation is a ubiquitous co- and post-translational modification which can alter the biological function of proteins and consequently affects the development, growth and physiology of organisms.
Richard eStrasser
doaj +1 more source
Improved method for drawing of a glycan map, and the first page of glycan atlas, which is a compilation of glycan maps for a whole organism. [PDF]
Glycan Atlas is a set of glycan maps over the whole body of an organism. The glycan map that includes data of glycan structure and quantity displays micro-heterogeneity of the glycans in a tissue, an organ, or cells. The two-dimensional glycan mapping is
Shunji Natsuka +3 more
doaj +1 more source
Lactoferrin (LF) is one of the most abundant bioactive glycoproteins in human milk. Glycans attached through N-glycosidic bonds may contribute to Lactoferrin functional activities. In contrast, LF is present in trace amounts in bovine milk.
Annabelle Le Parc +5 more
doaj +1 more source
Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including infections, in humans.
Laudine M. C. Petralia +10 more
doaj +1 more source
A Method to the Madness of N-Glycan Complexity? [PDF]
Cell-surface glycoprotein receptors have varying numbers of N-glycan sites. In this issue of Cell, Lau et al. (2007) report that increasing intracellular UDP-GlcNAc leads to increased branching of N-glycans, increased receptor association with cell-surface galectin-3, and enhanced signaling.
openaire +2 more sources
Identification and comparison of N-glycome profiles from common dietary protein sources
The N-glycomes of bovine whey, egg white, pea, and soy protein isolates are described here. N-glycans from four protein isolates were analyzed by HILIC high performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (HILIC ...
Matthew Bolino +6 more
doaj +1 more source

