Results 41 to 50 of about 13,562,347 (304)
Terminal Epitope-Dependent Branch Preference of Siglecs Toward N-Glycans
Frontiers in Molecular Biosciences, 2021 Siglecs are sialic acid–binding immunoglobulin-like lectins that play vital roles in immune cell signaling. Siglecs help the immune system distinguish between self and nonself through the recognition of glycan ligands.
Shuaishuai Wang +10 more
doaj +1 more source
N-glycan breakdown by bacterial CAZymes
Essays in Biochemistry, 2023 Abstract The modification of proteins by N-glycans is ubiquitous to most organisms and they have multiple biological functions, including protecting the adjoining protein from degradation and facilitating communication or adhesion between cells, for example. Microbes have evolved CAZymes to deconstruct different types of N-glycans and
openaire +2 more sources
Turkish Journal of Chemistry, 2022 Glycosylation is an essential posttranslational modification observed in the living proteome. Glycosylation profiles in glycoproteins can change in commonly observed diseases such as cancer. Identifying these changes is crucial in discovering new biomarkers for the early diagnosis of cancer.
SALİH, BEKİR +2 more
openaire +3 more sources
Revealing the evolution towards complex N-glycan specificities of human H1 influenza A viruses. [PDF]
, 2022 Influenza virus infection remains a threat to human health since viral hemagglutinins are constantly drifting, escaping infec-tion and vaccine-induced antibody responses.
James C, Paulson +11 more
core +2 more sources
Uncommon N-Glycan Structures in Anhydrobiotic Tardigrades. [PDF]
Mol Cell ProteomicsWe characterized the N-glycosylation profiles of anhydrobiotic tardigrades, Ramazzottius varieornatus and Hypsibius exemplaris, identifying high-mannose, paucimannose, and complex-type oligosaccharides, while hybrid-type glycans were undetectable. Notably, paucimannose-type oligosaccharides accounted for 39% of the N-glycans in R.
Yagi H +12 more
europepmc +4 more sources
, 2016 The N-glycan assay method quantifies the percent distribution of N-glycan species. Five key structures were quantified in samples generated from 5-L bioreactors were operated under normal (50%) and low (15%) DO conditions.
Nelly Aranibar (2208076) +10 more
core +1 more source
Glycan-specific median RF feature importance percentiles within pocket features.
, 2021 Median feature importance percentiles of pocket-based features (within the pocket features only) from each glycan-specific RF model determined via mean decrease in Gini impurity. Features with median importance in at least the 75th percentile (horizontal
Chris Bailey-Kellogg (682345) +1 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Proposed C. acnes 266 N-glycan-processing locus 1.
, 2018 Gene organization of the proposed N-glycan processing locus in the genome of C. acnes 266. GH genes predicted as mannosidases are colored green, and GH genes with predicted N-acetylhexosaminidase activity are blue.
Olov Svartström (447516) +5 more
core +1 more source
Glycan-specific median RF feature importance percentiles within residue features.
, 2021 Median feature importance percentiles of residue-based features (within the residue features only) from each glycan-specific RF model determined via mean decrease in Gini impurity.
Chris Bailey-Kellogg (682345) +1 more
core +1 more source