Results 171 to 180 of about 10,628,077 (304)

De novo determination of fucose linkages in N-glycans using logically derived sequence tandem mass spectrometry. [PDF]

Glycoconj J
Chen JL, Tseng HW, Lin CC, Ni CK.
europepmc   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

Therapy-induced remodeling of IgG and plasma N-glycans in breast cancer. [PDF]

BMC Cancer
Maričić Vrban M, Radovani Trbojević B, Visentin D, Ramljak K, Kirac I, Gaće M, Milas I, Lauc G, Primorac D, Gudelj I.   +9 more
europepmc   +1 more source

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source

Highly branched complex-type N-glycans on integrin β1 in extracellular vesicles enhance the binding of sEVs to laminin on recipient cells. [PDF]

J Biol Chem
Isogai T, Tokoro Y, Nakano M, Hirosawa KM, Kasai RS, Yokota Y, Kizuka Y, Suzuki KGN.   +7 more
europepmc   +1 more source

Qualitative Characterization of Neu5Gc-Containing N-Glycans in Commercial Cheddar Cheese Products Using Nano-UHPLC-ESI-MS/MS-A Pilot Study. [PDF]

Int J Mol Sci
Mogut D, Goli M, Reyes CDG, Mechref Y, Iwaniak A.   +4 more
europepmc   +1 more source

Optimizing the preparation of labeled N-glycans for rapid, simplified, and high-precision analysis. [PDF]

PLoS One
Makino R, Natsuka S.
europepmc   +1 more source

GLYCO-BUILD: an enzymatic pipeline for the synthesis of peptides carrying eukaryotic N-glycans. [PDF]

Nat Commun
Rossi L, Alexander JAN, Ramírez AS, Locher KP.   +3 more
europepmc   +1 more source

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

Structural analysis of isomeric N-glycans by ion mobility and negative ion fragmentation: applications to glycans released from fungi

, 2012
Little is known about the N-glycans present on the glycoproteins of basidiomycetes other than that they appear to consist mainly of the high-mannose glycans Man5-9GlcNAc2 with some other novel compounds present in a few species.
Scrivens, James H., Harvey, David J., Edgeworth, Matthew J., Allman, Sarah   +3 more
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