Results 131 to 140 of about 15,627,773 (170)

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling. [PDF]

Front Immunol
Tu J, Li X, Zhu Y, Li S, Zhang G, He Y, Zhang C, Lu Z.   +7 more
europepmc   +1 more source

Sialylation profile and Siglec-E expression across tissues in the B16OVA melanoma mouse model. [PDF]

Glycobiology
Coccimiglio M, Zhang T, Olesek K, Goossens-Kruijssen L, de Haan N, Chiodo F, van Kooyk Y.   +6 more
europepmc   +1 more source

Addition of human platelet lysate to islet culture medium suppresses islet loss and improves transplantation outcomes. [PDF]

Cell Transplant
Noguchi H, Miyagi-Shiohira C, Sadahira T, Watanabe M, Saitoh I.   +4 more
europepmc   +1 more source

Temporal and Sex-Dependent <i>N</i>-Glycosylation Dynamics in Rat Serum. [PDF]

Int J Mol Sci
Yagi H, Kondo S, Murakami R, Yogo R, Yanaka S, Umezawa F, Yagi-Utsumi M, Fujita A, Okina M, Hashimoto Y, Hotta Y, Kato Y, Nakajima K, Furukawa JI, Kato K.   +14 more
europepmc   +1 more source

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Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons

Xenotransplantation, 2021
AbstractPigs deficient in three glycosyltransferase enzymes (triple‐knockout [TKO] pigs) and expressing “protective” human transgenes are likely sources of organs for transplantation into human recipients. Testing of human sera against red blood cells (RBCs) and peripheral blood mononuclear cells (PBMCs) from TKO pigs has revealed minimal evidence of ...
Takayuki Yamamoto, Hayato Iwase, Abhijit Jagdale   +2 more
exaly   +3 more sources

Generation of recombinant anti-N-glycolylneuraminic acid (Neu5Gc) scFv and its applications for detection and quantitation of Neu5Gc

, 2016
Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation and in disease processes such as cancer progression.
Sharma, Rajesh Kumar
openaire   +2 more sources

Catalytic preference of Salmonella typhimurium LT2 sialidase for N-acetylneuraminic acid residues over N-glycolylneuraminic acid residues [PDF]

FEBS Open Bio, 2013
In a comparison of sialidase activities toward N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), we found that Salmonella typhimurium LT2 sialidase (STSA) hardly cleaved 4-methylumbelliferyl Neu5Gc (4MU-Neu5Gc).
Hiroaki Tokiwa, Takashi Suzuki
exaly   +2 more sources

Substitution of amino acid residue in influenza A virus hemagglutinin affects recognition of sialyl-oligosaccharides containing N-glycolylneuraminic acid [PDF]

FEBS Letters, 1999
Sialic acids are essential components of cell surface receptors used by influenza viruses. To determine the molecular mechanisms of viral recognition of two major species of sialic acids, N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid ...
Yoshihiro Kawaoka, Toshihiro Ito, Tetsuya Toyoda   +2 more
exaly   +2 more sources

Preparation of lauryl thioglycoside of N-glycolylneuraminic acid (Neu5Gc) as a useful glycosyl donor for assembly of an oligosaccharide containing Neu5Gc

Tetrahedron Letters, 2021
Abstract Efficient synthesis of lauryl thioglycoside of Neu5Gc was accomplished from a known thioglycoside of Neu5Ac. The reactivities of the Neu5Gc thioglycoside for O-glycosidation by means of TMSOTf-NIS as a promoter system were investigated, and the thioglycoside showed good activities with simple alcohols. In addition to the simple alcohols, the
Jianhong Zhang, Tetsuo Koyama, Takahiko Matsushita, Ken Hatano, Koji Matsuoka   +4 more
openaire   +1 more source